Anti-IL8 antibody [B-K8] (Phycoerythrin) (ab27369)

Overview

• Product nameAnti-IL8 antibody [B-K8] (Phycoerythrin)
  See all IL8 primary antibodies
• Description
  Mouse monoclonal [B-K8] to IL8 (Phycoerythrin)
• ConjugationPhycoerythrin. Ex: 488nm, Em: 575nm
• SpecificityRecognises both natural and recombinant IL8.
• Tested applicationsSuitable for: Flow Cytmore details
• Species reactivity
  Reacts with: Human
  
• Immunogen

  Recombinant full length IL8 (Human)

Properties

• FormLyophilised:Reconstitute with 1 ml deionized water
• Storage instructionsShipped at 4°C. Store at +4°C.
• Storage bufferPreservative: 0.1% Sodium Azide
  Constituents: 5% BSA, PBS
• Concentration information loading...
• PurityIon Exchange Chromatography
• ClonalityMonoclonal
• Clone numberB-K8
• Myelomax63-Ag8.653
• IsotypeIgG1
• Research areas
  • Cardiovascular
  • Angiogenesis
  • Cytokines
  • Interleukin

  • Immunology
  • Innate Immunity
  • Cytokines
  • Interleukins

  • Cancer
  • Invasion/microenvironment
  • Angiogenesis
  • Angiogenic growth factors

Associated products

• Compatible Secondaries
  • Goat Anti-Mouse IgG H&L (Alexa Fluor® 488) (ab150113)
  • Goat Anti-Mouse IgG H&L (HRP) (ab205719)

Applications

Target

• FunctionIL-8 is a chemotactic factor that attracts neutrophils, basophils, and T-cells, but not monocytes. It is also involved in neutrophil activation. It is released from several cell types in response to an inflammatory stimulus. IL-8(6-77) has a 5-10-fold higher activity on neutrophil activation, IL-8(5-77) has increased activity on neutrophil activation and IL-8(7-77) has a higher affinity to receptors CXCR1 and CXCR2 as compared to IL-8(1-77), respectively.
• Sequence similaritiesBelongs to the intercrine alpha (chemokine CxC) family.
• Post-translational
  modificationsSeveral N-terminal processed forms are produced by proteolytic cleavage after secretion from at least peripheral blood monocytes, leukcocytes and endothelial cells. In general, IL-8(1-77) is referred to as interleukin-8. IL-8(6-77) is the most promiment form.
• Cellular localizationSecreted.

• Target information above from: UniProt accession P10145 The UniProt Consortium
  The Universal Protein Resource (UniProt) in 2010
  Nucleic Acids Res. 38:D142-D148 (2010) .

  Information by UniProt
• Database links
  • Entrez Gene: 3576 Human
  • Omim: 146930 Human
  • SwissProt: P10145 Human
  • Unigene: 624 Human
• Alternative names
  • (Ala-IL-8)77 antibody
  • (Ser-IL-8)72 antibody
  • 9E3 antibody

  • Beta thromboglobulin like protein antibody
  • C-X-C motif chemokine 8 antibody
  • CEF-4 antibody
  • chemokine, CXC motif, ligand 8 antibody
  • CXCL8 antibody
  • Emoctakin antibody
  • GCP-1 antibody
  • GCP/IL-8 protein I antibody
  • GCP/IL-8 protein II antibody
  • GCP/IL-8 protein III antibody
  • GCP/IL-8 protein IV antibody
  • GCP/IL-8 protein V antibody
  • GCP/IL-8 protein VI antibody
  • GCP1 antibody
  • Granulocyte chemotactic protein 1 antibody
  • IL-8 antibody
  • IL-8(1-77) antibody
  • IL-8(9-77) antibody
  • IL8 antibody
  • IL8/NAP1 form I antibody
  • IL8/NAP1 form II antibody
  • IL8/NAP1 form III antibody
  • IL8/NAP1 form IV antibody
  • IL8/NAP1 form V antibody
  • IL8/NAP1 form VI antibody
  • IL8_HUMAN antibody
  • Inteleukin 8 antibody
  • LECT antibody
  • LUCT antibody
  • Lymphocyte-derived neutrophil-activating factor antibody
  • LYNAP antibody
  • MDNCF antibody
  • MDNCF-b antibody
  • MDNCF-c antibody
  • MONAP antibody
  • Monocyte-derived neutrophil chemotactic factor antibody
  • Monocyte-derived neutrophil-activating peptide antibody
  • NAF antibody
  • NAP-1 antibody
  • NAP1 antibody
  • Neutrophil activating peptide 1 antibody
  • Neutrophil activating protein 1 antibody
  • Neutrophil-activating factor antibody
  • Neutrophil-activating protein 1 antibody
  • Protein 3 10C antibody
  • Protein 3-10C antibody
  • SCYB8 antibody
  • Small inducible cytokine subfamily B member 8 antibody
  • T cell chemotactic factor antibody
  • T-cell chemotactic factor antibody
  • TSG1 antibody

  see all