The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/50 - 1/100.
FunctionThis is a receptor for interleukin-9.
Sequence similaritiesBelongs to the type I cytokine receptor family. Type 4 subfamily. Contains 1 fibronectin type-III domain.
DomainThe WSXWS motif appears to be necessary for proper protein folding and thereby efficient intracellular transport and cell-surface receptor binding. The box 1 motif is required for JAK interaction and/or activation.
ab61196 at 1/50 dilution staining IL9R in human lymph node by Immunohistochemistry, Paraffin-embedded tissue, in the absence (left) or presence (right) of the immunising peptide.
References for Anti-IL9R antibody (ab61196)
This product has been referenced in:
Vieyra-Garcia PA et al. STAT3/5-Dependent IL9 Overexpression Contributes to Neoplastic Cell Survival in Mycosis Fungoides. Clin Cancer Res22:3328-39 (2016).
Read more (PubMed: 26851186) »
Singh TP et al. Involvement of IL-9 in Th17-associated inflammation and angiogenesis of psoriasis. PLoS One8:e51752 (2013).
Read more (PubMed: 23335955) »