Overview

  • Product name
    Iloprost
  • Description
    Prostaglandin (PGI2) analog
  • Alternative names
    • ZK 36374
  • Biological description
    Prostaglandin (PGI2) analog. Binds with high affinity to the human recombinant IP, EP1 and EP3 receptors (Ki values are 11 (IP and EP1) and 56 nM (EP3)). Higher selectivity over other prostanoid receptors.
  • Purity
    > 97%

Properties

  • Chemical name
    (5E)-5-[(3aS,4R,5R,6aS)-Hexahydro-5-hydroxy-4-[(1E,3S)-3-hydroxy-4-methyl-1-octen-6-yn-1-yl]-2(1H)-pentalenylidene]pentanoic acid
  • Molecular weight
    360.49
  • Chemical structure
    Chemical Structure
  • Molecular formula
    C22H32O4
  • CAS Number
    78919-13-8
  • Storage instructions
    Store at -20°C (desiccating conditions).
  • Solubility overview
    Supplied in methyl acetate (5 mg/ml)
  • Handling

    Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 6 months. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES
    O[C@@H]1C[C@H](C/2)[C@H](CC2=CCCCC(O)=O)[C@H]1/C=C/[C@@H](O)C(C)CC#CC
  • Source

    Synthetic

  • Research areas

References

This product has been referenced in:
  • Della Bella S  et al. Novel mode of action of iloprost: in vitro down-regulation of endothelial cell adhesion molecules. Prostaglandins Other Lipid Mediat 65:73-83 (2001). Read more (PubMed: 11403500) »
  • Abramovitz M  et al. The utilization of recombinant prostanoid receptors to determine the affinities and selectivities of prostaglandins and related analogs. Biochim Biophys Acta 1483:285-93 (2000). Read more (PubMed: 10634944) »

See 0 Publications for this product

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab120911.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE, NOT FOR USE IN HUMANS"

Sign up