Overview

  • Product nameIloprost
  • Description
    Prostaglandin (PGI2) analog
  • Alternative names
    • ZK 36374
  • Biological descriptionProstaglandin (PGI2) analog. Binds with high affinity to the human recombinant IP, EP1 and EP3 receptors (Ki values are 11 (IP and EP1) and 56 nM (EP3)). Higher selectivity over other prostanoid receptors.
  • Purity> 97%

Properties

  • Chemical name(5E)-5-[(3aS,4R,5R,6aS)-Hexahydro-5-hydroxy-4-[(1E,3S)-3-hydroxy-4-methyl-1-octen-6-yn-1-yl]-2(1H)-pentalenylidene]pentanoic acid
  • Molecular weight360.49
  • Chemical structureChemical Structure
  • Molecular formulaC22H32O4
  • CAS Number78919-13-8
  • Storage instructionsStore at -20°C (desiccating conditions).
  • Solubility overviewSupplied in methyl acetate (5 mg/ml)
  • Handling

    Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 6 months. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILESO[C@@H]1C[C@H](C/2)[C@H](CC2=CCCCC(O)=O)[C@H]1/C=C/[C@@H](O)C(C)CC#CC
  • Source

    Synthetic

  • Research areas

    References for Iloprost (ab120911)

    This product has been referenced in:
    • Della Bella S  et al. Novel mode of action of iloprost: in vitro down-regulation of endothelial cell adhesion molecules. Prostaglandins Other Lipid Mediat 65:73-83 (2001). Read more (PubMed: 11403500) »
    • Abramovitz M  et al. The utilization of recombinant prostanoid receptors to determine the affinities and selectivities of prostaglandins and related analogs. Biochim Biophys Acta 1483:285-93 (2000). Read more (PubMed: 10634944) »

    See 0 Publications for this product

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE, NOT FOR USE IN HUMANS"