Overview

  • Product name
    Anti-IMP5 antibody
  • Description
    Rabbit polyclonal to IMP5
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide corresponding to a region within internal amino acids 575-624 (NPGEDTTEIV TISENEATNP EDRSDSSEGW SDAHLDPNEL PFIPPGASEE) of Human IMP5 (NP_787078)

  • Positive control
    • Human fetal thymus lysate

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
  • Storage buffer
    Preservative: None
    Constituents: 2% Sucrose, PBS
  • Concentration information loading...
  • Purity
    Immunogen affinity purified
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab98157 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 75 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

Target

  • Function
    Intramembrane-cleaving aspartic protease (I-CLiP) that may be able to cleave type II membrane signal peptides in the hydrophobic plane of the membrane.
  • Tissue specificity
    Ubiquitous.
  • Sequence similarities
    Belongs to the peptidase A22B family.
    Contains 1 PA (protease associated) domain.
  • Domain
    The PAL motif is required for normal active site conformation. The catalytic domains embedded in the membrane are in the opposite orientation to that of the presenilin protein family; therefore, it is predicted to cleave type II-oriented substrate peptides like the prototypic protease SPP.
  • Post-translational
    modifications
    Glycosylated.
  • Cellular localization
    Endoplasmic reticulum membrane. Membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • IMP-5 antibody
    • Intramembrane protease 5 antibody
    • Signal peptide peptidase-like 2C antibody
    • SPP-like 2C antibody
    • SPP2C_HUMAN antibody
    • SPPL2C antibody
    see all

Anti-IMP5 antibody images

  • Anti-IMP5 antibody (ab98157) at 1 µg/ml + Human fetal thymus lysate at 10 µg

    Predicted band size : 75 kDa

References for Anti-IMP5 antibody (ab98157)

ab98157 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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