Overview

  • Product nameAnti-IMPDH2 antibody
    See all IMPDH2 primary antibodies
  • Description
    Rabbit polyclonal to IMPDH2
  • Tested applicationsSuitable for: ICC/IF, WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Rabbit, Horse, Chicken, Guinea pig, Cow, Cat, Dog, Zebrafish
  • Immunogen

    Synthetic peptide corresponding to a region within N terminal amino acids 1-50 (MADYLISGGT SYVPDDGLTA QQLFNCGDGL TYNDFLILPG YIDFTADQVD) of Human IMPDH2 (NP_000875).

  • Positive control
    • 721_B cell lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab104290 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ICC/IF 1/500.
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 56 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

Target

  • FunctionRate limiting enzyme in the de novo synthesis of guanine nucleotides and therefore is involved in the regulation of cell growth. It may also have a role in the development of malignancy and the growth progression of some tumors.
  • Tissue specificityIMP type I is the main species in normal leukocytes and type II predominates over type I in the tumor.
  • PathwayPurine metabolism; XMP biosynthesis via de novo pathway; XMP from IMP: step 1/1.
  • Sequence similaritiesBelongs to the IMPDH/GMPR family.
    Contains 2 CBS domains.
  • Post-translational
    modifications
    The N-terminus is blocked.
  • Information by UniProt
  • Database links
  • Alternative names
    • IMDH2_HUMAN antibody
    • IMP (inosine monophosphate) dehydrogenase 2 antibody
    • IMP dehydrogenase 2 antibody
    • IMP oxireductase 2 antibody
    • IMPD 2 antibody
    • IMPD2 antibody
    • IMPDH 2 antibody
    • IMPDH II antibody
    • IMPDH-II antibody
    • Impdh2 antibody
    • Inosine 5' monophosphate dehydrogenase 2 antibody
    • Inosine 5' phosphate dehydrogenase 2 antibody
    • Inosine monophosphate dehydrogenase type II antibody
    • Inosine-5''-monophosphate dehydrogenase 2 antibody
    see all

Anti-IMPDH2 antibody images

  • Sample Type : Human Hep-2 cells. Primary Antibody Dilution : 1:500. Secondary Antibody : Goat anti-rabbit-Alexa Fluor 568. Secondary Antibody Dilution : 1:400. Color/Signal Descriptions : Red: IMPDH2 Blue: DAPI.

  • Anti-IMPDH2 antibody (ab104290) at 1 µg/ml + 721_B cell lysate at 10 µg

    Predicted band size : 56 kDa

References for Anti-IMPDH2 antibody (ab104290)

ab104290 has not yet been referenced specifically in any publications.

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