Overview

  • Product nameAnti-IMPDH2 antibody
    See all IMPDH2 primary antibodies
  • Description
    Mouse polyclonal to IMPDH2
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Full length native protein (purified), corresponding to amino acids 1-514 of Human IMPDH2

Properties

Applications

Our Abpromise guarantee covers the use of ab70045 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/1000. Detects a band of approximately 56 kDa (predicted molecular weight: 56 kDa).

Target

  • FunctionRate limiting enzyme in the de novo synthesis of guanine nucleotides and therefore is involved in the regulation of cell growth. It may also have a role in the development of malignancy and the growth progression of some tumors.
  • Tissue specificityIMP type I is the main species in normal leukocytes and type II predominates over type I in the tumor.
  • PathwayPurine metabolism; XMP biosynthesis via de novo pathway; XMP from IMP: step 1/1.
  • Sequence similaritiesBelongs to the IMPDH/GMPR family.
    Contains 2 CBS domains.
  • Post-translational
    modifications
    The N-terminus is blocked.
  • Information by UniProt
  • Database links
  • Alternative names
    • IMDH2_HUMAN antibody
    • IMP (inosine monophosphate) dehydrogenase 2 antibody
    • IMP dehydrogenase 2 antibody
    • IMP oxireductase 2 antibody
    • IMPD 2 antibody
    • IMPD2 antibody
    • IMPDH 2 antibody
    • IMPDH II antibody
    • IMPDH-II antibody
    • Impdh2 antibody
    • Inosine 5' monophosphate dehydrogenase 2 antibody
    • Inosine 5' phosphate dehydrogenase 2 antibody
    • Inosine monophosphate dehydrogenase type II antibody
    • Inosine-5''-monophosphate dehydrogenase 2 antibody
    see all

Anti-IMPDH2 antibody images

  • All lanes : Anti-IMPDH2 antibody (ab70045) at 1/500 dilution

    Lane 1 : IMPDH2-transfected 293T cell line lysate
    Lane 2 : non-transfected 293T cell line lysate


    Predicted band size : 56 kDa
    Observed band size : 56 kDa

References for Anti-IMPDH2 antibody (ab70045)

ab70045 has not yet been referenced specifically in any publications.

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