Overview

  • Product nameAnti-IMPDH2 antibody
    See all IMPDH2 primary antibodies
  • Description
    Goat polyclonal to IMPDH2
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Chinese Hamster
  • Immunogen

    Synthetic peptide:

    KEEEHDCFLEEI

    , corresponding to internal sequence amino acids 167-178 of Human IMPDH2 (NP_000875.2).

  • Positive control
    • Human Skeletal Muscle lysate.

Properties

Applications

Our Abpromise guarantee covers the use of ab85702 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 - 3 µg/ml. Detects a band of approximately 60 kDa (predicted molecular weight: 56 kDa).

Target

  • FunctionRate limiting enzyme in the de novo synthesis of guanine nucleotides and therefore is involved in the regulation of cell growth. It may also have a role in the development of malignancy and the growth progression of some tumors.
  • Tissue specificityIMP type I is the main species in normal leukocytes and type II predominates over type I in the tumor.
  • PathwayPurine metabolism; XMP biosynthesis via de novo pathway; XMP from IMP: step 1/1.
  • Sequence similaritiesBelongs to the IMPDH/GMPR family.
    Contains 2 CBS domains.
  • Post-translational
    modifications
    The N-terminus is blocked.
  • Information by UniProt
  • Database links
  • Alternative names
    • IMDH2_HUMAN antibody
    • IMP (inosine monophosphate) dehydrogenase 2 antibody
    • IMP dehydrogenase 2 antibody
    • IMP oxireductase 2 antibody
    • IMPD 2 antibody
    • IMPD2 antibody
    • IMPDH 2 antibody
    • IMPDH II antibody
    • IMPDH-II antibody
    • Impdh2 antibody
    • Inosine 5' monophosphate dehydrogenase 2 antibody
    • Inosine 5' phosphate dehydrogenase 2 antibody
    • Inosine monophosphate dehydrogenase type II antibody
    • Inosine-5''-monophosphate dehydrogenase 2 antibody
    see all

Anti-IMPDH2 antibody images

  • Anti-IMPDH2 antibody (ab85702) at 1 µg/ml + Human Skeletal Muscle lysate (in RIPA buffer) at 35 µg
    Developed using the ECL technique

    Predicted band size : 56 kDa
    Observed band size : 60 kDa (why is the actual band size different from the predicted?)

References for Anti-IMPDH2 antibody (ab85702)

ab85702 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab85702.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"