Cardiac Development and Regeneration symposium

Register and submit your abstract now!

Wnt/beta-catenin signaling in cardiac development

In honor of this meeting, we have just released the latest in our series of Cardiovascular-related pathway cards.

Wnt signaling controls crucial aspects of cardiovascular biology including cardiac morphogenesis, and the self-renewal and differentiation of cardiac progenitor cells. As shown on our new pathway card, the ability of Wnt signaling to regulate such different aspects of cardiovascular development rests on the diverse downstream targets affected by this pathway.

Download the pathway

Venue:

Doubletree Guest Suites Boston
400 Soldiers Field Road (map)
Boston, Massachusetts

Date:

October 10 - 1, 2008

Time:

October 10th: 9:00am to 5:00pm
October 11th: 9:00am to 5:00pm
Please join us after the meeting on October 10th for a reception and poster session.

Organizers:

Dr. Jonathan Epstein, M.D. and Dr. Edward Morrisey, Ph.D. in association with Abcam, Inc.

Contents:

Topics
Invited speakers
Oral presentations selected from submitted abstracts
Program
Registration
Posters
Accommodation
Directions to venue
Public transportation
Sponsorship
Contact information

Topics:

Early cardiovascular development
Epigenetics
Reprogramming and cardiac progenitors
Genomics
Molecular pathways and congenital heart disease
Cardiac stem cells and regeneration

Invited speakers:

Keynote: Cliff Tabin, Chairman, Department of Genetics, Harvard Medical School
Morphogenesis of the heart and other organs
Margaret Buckingham, Department of Developmental Biology, Pasteur Institute, France
Cardiac progenitor cells of the second heart field in the mouse embryo
Deepak Srivastava, Gladstone Institute, UCSF
microRNA regulation of cardiac stem cells and regeneration
Benoit Bruneau, Gladstone Institute, UCSF
Chromatin remodeling in heart development
William Pu, Children's Hospital of Boston, Harvard Medical School
Epicardial-derived Wt1+ progenitors contribute to the cardiomyocyte lineage in the embryonic and adult heart
Debbie Yelon, Skirball Institute, New York University School of Medicine
Signaling pathways that shape the heart field in zebrafish
Stephen Duncan, Medical College of Wisconsin
Control of cardiac development by Gata4 and Gata6
Michael Parmacek, Division of Cardiovascular Medicine, University of Pennsylvania
Myocardin related transcription factors: Critical co-activators regulating heart and outflow tract development
Nathan Lawson, University of Massachusetts Medical School
Transcriptional control of endothelial cell identity
Sean Wu, Cardiovascular Research Center, Massachusetts General Hospital
iPS, ES, or endogenous cells in cardiac regeneration
Kenneth Chien, Massachusetts General Hospital Cardiovascular Research Center
Towards human models of human heart disease: The islet-1 heart progenitor story
John Mably, Children’s Hospital, Boston
Genetic regulation of cardiac development in zebrafish
Edward Morrisey, University of Pennsylvania
Wnt signaling and regulation of cardiac and lung development
Jonathan Epstein, University of Pennsylvania
Notch signaling in cardiovascular development

Oral presentations selected from submitted abstracts:

José Luis de la Pompa, Centro Nacional de Biotecnología
Notch signalling in cardiac valve development
Carolyn Gaydos, Tufts University
Notch signaling regulates cell fate decisions during cardiac field formation in Xenopus laevis
Lisa Chang, Baker IDI Heart and Diabetes Research Institute
Contextual dependent reprogramming of the SWI/SNF complex allows it to differentially serve as a transcriptional co-regulator at promoters of the hypertrophied heart
Ivan Moskowitz, University of Chicago
Hedgehog-dependent atrial septum progenitors are required for cardiac septation
Patricia Labosky, Vanderbilt University
Progenitor pool size is not a critical determinant of cardiac neural crest function
Rolf Bodmer, Burnham Institute for Medical Research
Discovering cardiac disease genes in Drosophila
Neil Chi, University of California, San Francisco
Foxn4 directly regulates tbx2b expression for the evolutionary division of the vertebrate heart
Steven Kattman, McEwen Centre for Regenerative Medicine
Establishment of cardiac mesoderm is regulated by ActivinA and BMP4 during mouse and human ES and iPS cell differentiation
Ian Scott, The Hospital for Sick Children
Regulation of cardiac progenitor development by Agtrl1 signaling in zebrafish
Benjamin Herdrich, Children’s Hospital of Philadelphia
Regenerative healing following fetal myocardial infarction
Laura Zelarayan, Max Delbrueck Center for Molecular Medicine
Inhibition of ß-catenin attenuates left ventricular remodeling after myocardial infarction through enhanced cardiac stem cell differentiation

Program:

Full schedule also available for pdf download.

Friday, October 10, 2008
8:00am	Registration
9:00am	Welcome, meeting chairs
9:10am	Keynote: Morphogenesis of the heart and other organs Cliff Tabin, Chairman, Department of Genetics, Harvard Medical School
9:50am	Control of cardiac development by Gata4 and Gata6 Stephen Duncan, Medical College of Wisconsin
10:25am	Chromatin remodeling in heart development Benoit Bruneau, Gladstone Institute, UCSF
11:10am	Coffee break
11:40am	Towards human models of human heart disease: The islet-1 heart progenitor story Kenneth Chien, Massachusetts General Hospital Cardiovascular Research Center
12:15pm	Notch signaling regulates cell fate decisions during cardiac field formation in Xenopus laevis Carolyn Gaydos, Tufts University
12:35pm	Notch signalling in cardiac valve development José Luis de la Pompa, Centro Nacional de Biotecnología
12:55pm	Lunch
1:55pm	Myocardin related transcription factors: Critical co-activators regulating heart and outflow tract development Michael Parmacek, Division of Cardiovascular Medicine, University of Pennsylvania
2:30pm	Epicardial-derived Wt1+ progenitors contribute to the cardiomyocyte lineage in the embryonic and adult heart William Pu, Children’s Hospital of Boston, Harvard Medical School
3:05pm	Coffee break
3:35pm	microRNA regulation of cardiac stem cells and regeneration Deepak Srivastava, Gladstone Institute, UCSF
4:10pm	Contextual dependent reprogramming of the SWI/SNF complex allows it to differentially serve as a transcriptional co-regulator at promoters of the hypertrophied heart Lisa Chang, Baker IDI Heart and Diabetes Research Institute
4:30pm	Transcriptional control of endothelial cell identity Nathan Lawson, University of Massachusetts Medical School
5:05pm	Reception and poster session

Saturday, October 11, 2008
9:00am	Cardiac progenitor cells of the second heart field in the mouse embryo Margaret Buckingham, Department of Developmental Biology, Pasteur Institute, France
9:35am	Hedgehog-dependent atrial septum progenitors are required for cardiac septation Ivan Moskowitz, University of Chicago
9:55am	Progenitor pool size is not a critical determinant of cardiac neural crest function Patricia Labosky, Vanderbilt University
10:15am	Coffee break
10:45am	Signaling pathways that shape the heart field in zebrafish Debbie Yelon, Skirball Institute, New York University School of Medicine
11:20am	iPS, ES or endogenous cells in cardiac regeneration Sean Wu, Cardiovascular Research Center, Massachusetts General Hospital
11:55am	Discovering cardiac disease genes in Drosophila Rolf Bodmer, Burnham Institute for Medical Research
12:15am	Foxn4 directly regulates tbx2b expression for the evolutionary division of the vertebrate heart Neil Chi, University of California, San Francisco
12:35pm	Lunch
1:30pm	Notch signaling in cardiovascular development Jonathan Epstein, University of Pennsylvania
2:05pm	Genetic regulation of cardiac development in zebrafish John Mably, Children’s Hospital, Boston
2:40pm	Establishment of cardiac mesoderm is regulated by ActivinA and BMP4 during mouse and human ES and iPS cell differentiation Steven Kattman, McEwen Centre for Regenerative Medicine
3:00pm	Coffee break
3:25pm	Wnt signaling and regulation of cardiac and lung development Edward Morrisey, University of Pennsylvania
4:00pm	Regulation of cardiac progenitor development by Agtrl1 signaling in zebrafish Ian Scott, The Hospital for Sick Children
4:20pm	Regenerative healing following fetal myocardial infarction Benjamin Herdrich, University of Pennsylvania School of Medicine
4:40pm	Inhibition of ß-catenin attenuates left ventricular remodeling after myocardial infarction through enhanced cardiac stem cell differentiation Laura Zelarayan, Max Delbrueck Center for Molecular Medicine

Registration:

	Early Bird Register by August 10, 2008	Standard Register after August 10, 2008
Regular	$190.00	$250.00
Student	$125.00	$175.00

The registration fee includes lunch and coffee on both days and a wine reception on October 10th. Register and submit your abstract online.

Students are categorized as those in full-time education at the time of registering. Proof of student status may be requested.

If you are paying via American Express, please contact Katie via email or at 617-577-4263 since we cannot take the cards online at the moment.

Posters:

A full list of registered posters including title and presentor is available for download. PDF

Posters will be judged. The winner will receive up to $150 off their registration for a future Abcam conference or an antibody from the Abcam catalog.

Posters must not be larger than four feet tall by four feet wide.

Flier:

Download the flier for the meeting. PDF (Warning - large file)

Feel free to print it out and distribute it at your organization.

Accommodation:

A block of rooms at the Doubletree Guest Suites Boston have been set aside. Please contact the hotel at 1-800-222-8733 and mention "Abcam" to reserve your room at a special rate. Rooms must be reserved by Monday, September 8, 2008 to take advantage of this special price. You can also reserve your room online.

Directions to venue:

The hotel is located just off I-90 (Mass Turnpike).

East Bound: take Exit 18-Brighton/Cambridge.
West Bound: take Exit 20-Brighton/Cambridge.

From Logan International Airport, exit via the Ted Williams Tunnel, follow sign to I-90W and take Exit 20-Brighton/Cambridge, after paying toll, bear right towards Cambridge. At second light turn right, hotel driveway is on your right.

A taxi from Logan International Airport is approximately $30.00.

Here are detailed instructions on how to get to the DoubleTree Hotel Boston. For maps please see the venue's website.

Public transportation:

The Doubletree is close to many MBTA bus stops. Visit the MBTA web site for more information.

Sponsorship:

If you are interested in sponsoring or exhibiting at this meeting, please contact us for more information.

For more information:

Katie Sedat, Abcam Events Team
Phone: 617-577-4263

Register and submit your abstract now!

Cancellation Terms and Conditions
Delegates are advised to ensure they have adequate travel insurance to cover their attendance at the conference in case of incident, or cancellation due to circumstances beyond Abcam's control.

All fees paid to Abcam, including registration are non-refundable.
Substitute delegates can be made at any time by contacting events@abcam.com.

Check out our other upcoming Cardiovascular meeting:

Molecular Regulation of Cardiac Disease symposium
May 14 - 15, 2009 - London, UK
View meeting details and register.

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Cardiac Development and Regeneration symposium