ROS modulators

Code

Name

Details

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Allopurinol sodium 

Xanthine oxidase inhibitor

 
 
 
 

2-Aminobiphenyl 

Mutagenic agent

 
 
 
 

N-Amyl-N-methylnitrosamine 

Esophageal-selective mutagenic agent

 
 
 
 

Apocynin 

Selective NADPH-oxidase inhibitor

Purity: > 99%

Images
 
Specific publication references
 
 
 

Artemisinin 

Antimalarial compound

Purity: > 99%

 
 
 
 

BHHCT 

Fluorescent sensitizer for Eu3+- labelling

Purity: > 90%

 
 
 
 

CAY10598 

Potent, selective EP4 agonist

Purity: > 98%

 
 
 
 

Coelenterazine, native 

Cell-permeable aequorin luminophore. Chemiluminescent superoxide anion indicator.

 
 
 
 

Cyclosporin H 

TPA/PMA inhibitor

Purity: > 96%

 
Specific publication references
 
 
 

2-Deoxy-D-glucose 

Non-metabolizable glucose analog and glycolytic inhibitor. Antitumor agent.

Purity: > 98%

 
Specific publication references
 
 
 

DEPMPO 

Spin trap

Purity: > 99%

 
 
 
 

Diallyl tetrasulfide 

JNK activator. ROS inducer.

Purity: > 90%

 
 
 
 

2,7-Dichlorofluorescein 

Intracellular fluorescent label

 
 
 
 

Diethyldithiocarbamic acid sodium salt trihydrate 

Superoxide dismutase (SOD) and NF-κB inhibitor

 
 
 
 

Dihydroethidium (DHE) 

Cell-permeable blue fluorescent dye. Redox indicator.

Purity: > 98%

 
 
 
 

Dihydrofluorescein diacetate 

Fluorescent intracellular oxidant probe. Redox sensor.

Purity: > 97%

 
 
 
 

Dihydrorhodamine 123 

Cell-permeable fluorescent probe for ROS

Purity: > 95%

 
 
 
 

D-threo-Dihydrosphingosine 

Sphingosine kinase inhibitor

Purity: > 98%

 
 
 
 

DMNQ 

Cell-permeable non-alkyiating redox cycling quinone

Purity: > 99%

 
 
 
 

DMSA (Meso-2,3-dimercaptosuccinic acid) 

Lead chelating agent and ROS° scavenger

Purity: > 98%

 
 
 
 

Edaravone (MCI-186) 

Free radical scavenger with neuroprotective effects

Purity: > 99%

 
 
 
 

Erdosteine 

Thiol derivative. Expectorant and antioxidant.

Purity: > 98%

 
 
 
 

Febuxostat 

Highly potent, selective, non-competitive, non-purine xanthine oxidase inhibitor

Purity: > 98%

 
 
 
 

FeTPPS 

Selective peroxynitrite decomposition catalyst and scavenger

Purity: > 95%

 
Specific publication references
 
 
 

DL-Homocysteine thiolactone hydrochloride 

Erdosteine and citiolone intermediate

Purity: > 98%

 
 
 
 

Honokiol 

Anti-inflammatory and chemotherapeutic agent

Purity: > 98%

Images
 
 
 
 

Lactofen 

Herbicidal and tumorigenic agent

Purity: > 99%

 
 
 
 

Linoleic acid 

Essential polyunsaturated fatty acid. PPAR activator.

Purity: > 99%

 
 
 
 

γ-Linolenic acid 

Unsaturated fatty acid

 
 
 
 

Lucigenin 

Selective superoxide anion radical chemiluminescent probe

Purity: > 98%

 
 
 
 

Melittin 

Cationic antimicrobial peptide. Membrane-disruptive and apoptotic agent.

Purity: > 98%

 
 
 
 

S-Methyl-L-cysteine 

System A and <>1 inhibitor

Purity: > 99%

 
 
 
 

(±)-Miconazole nitrate 

Imidazole antifungal agent

Purity: > 99%

 
 
 
 

MnTBAP chloride 

Cell-permeable superoxide dismutase (SOD) mimetic

 
 
 
 

Notoginsenoside R1 

Phytoestrogen, inhibits TNF-α-induced PAI-1

Purity: > 98%

 
 
 
 

Patulin 

Fungal mycotoxin, DNA damaging agent and induces ROS production

Purity: > 98%

 
 
 
 

Phenethyl isothiocyanate 

Cell cycle arrest and apoptosis inducer in cancer cells

Purity: > 98%

 
 
 
 

Piperlongumine 

Constituent of Piper longum. Shows antitumor activity.

Purity: > 97%

 
 
 
 

Protocatechuic aldehyde 

Potent, water-soluble free radical scavenger

Purity: > 98%

 
 
 
 

Puromycin aminonucleoside 

Podocyte toxin, induces ROS and oxidant-dependent DNA damage

Purity: > 98%

 
 
 
 

Reduced Glutathione (GSH) 

Endogenous antioxidant

Purity: > 99%

 
 
 
 

Streptochlorin 

Potent antiangiogenic agent

Purity: > 95%

 
 
 
 

TCEP hydrochloride (tris(2-carboxyethyl)phosphine hydrochloride) 

Non-thiol reducing reagent

Purity: > 97%

 
 
 
 

D,L-Thioctic acid (DL-alpha-Lipoic acid) 

Non-specific free radical scavenger. Anti-oxidant.

Purity: > 98%

 
 
 
 
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