Receptor tyrosine kinases

Code

Name

Details

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AAL 993 

Potent, selective and cell-permeable VEGFR inhibitor

Purity: > 98%

 
 
 
 

N-Acetyl-3-O-methyl-D-glucosamine (3-O-Methyl-N-acetyl-D-glucosamine) 

Competitive N-acetylglucosamine kinase. N-acetylmannosamine kinase inhibitor

 
 
 
 
  

Afatinib (BIBW 2992) 

Potent, irreversible Her2/ErbB 2 and EGFR kinase inhibitor

Purity: > 99%

 
 
 
 
  

AG-370 

Selective PDGFR tyrosine kinase inhibitor

Purity: > 99%

 
 
 
 
  

AG-494 

Potent, selective EGF receptor tyrosine kinase

Purity: > 99%

 
 
 
 
  

AG-1024 

Selective IGF-1 receptor inhibitor. Potent antiproliferative agent.

Purity: > 99%

 
 
 
 
  

AG 1296 

Potent specific PDGF receptor tyrosine kinase inhibitor

Purity: > 99%

 
 
 
 
  

AG 1478 

Selective EGF receptor tyrosine kinase inhibitor

Purity: > 98%

 
 
 
 

AG 555 (Tyrphostin B46) 

Potent EGFR-tyrosine kinase inhibitor

Purity: > 98%

 
 
 
 

AG 556 (Tyrphostin B56) 

Selective EGFR inhibitor

Purity: > 95%

 
 
 
 
  

AG-879 

Selective TrkA receptor inhibitor

Purity: > 99%

 
 
 
 
  

BIBW2992 (Afatinib) 

Potent, irreversible ATP-competitive ErbB inhibitor. Antitumor.

Purity: > 99%

 
 
 
 
  

BMS-599626 (AC480) 

Selective HER1 and HER2 inhibitor

Purity: > 99%

 
 
 
 
  

Canertinib (CI-1033) 

Potent irreversible EGFR and HER2/ErbB2 tyrosine kinase inhibitor

Purity: > 99%

 
 
 
 
  

Chromium picolinate 

Insulin potentiator

Purity: > 98%

 
 
 
 
  

CP-724714 

Potent, selective HER2/ErbB2 inhibitor

Purity: > 95%

 
 
 
 
  

7,8-Dihydroxyflavone (7,8-DHF) 

Selective TrkB receptor agonist. Flavonoid.

Purity: > 99%

 
 
 
 
  

DMPQ dihydrochloride 

Potent and selective PDGFRβ inhibitor

Purity: > 99%

 
 
 
 
  

DMXAA (ASA404) 

Vascular disrupting agent. VEGFR inhibitor.

Purity: > 99%

 
 
 
 
  

Erbstatin Analog 

EGFR tyrosine kinase inhibitor

Purity: > 98%

 
 
 
 
  

(R)-Flurbiprofen (Tarenflurbil) 

γ-secretase inhibitor

Purity: > 99%

 
 
 
 
  

Gambogic amide 

Potent, selective high affinity nerve growth factor (TrKa) receptor agonist

Purity: > 98%

 
 
 
 
  

Genistein 

Protein tyrosine kinase inhibitor. Anticancer agent.

Purity: > 99%

 
Specific publication references
 
 
 
  

6-Gingerol 

Apoptotic, antioxidant and anti-inflammatory agent. SERCA activator.

Purity: > 98%

 
 
 
 
  

Glipizide 

Sulfonylurea receptor and ATP-sensitive K+ channel blocker

Purity: > 98%

 
 
 
 
  

Glucagon (19-29) (human) 

C-terminal fragment of Glucagon. Potent Ca2+/Mg2+-ATPase inhibitor.

Purity: > 95%

 
 
 
 
  

GW 2580 

Selective cFMS RTK inhibitor. Cell-permeable.

Purity: > 99%

 
 
 
 
  

HNMPA-(AM)3 

Insulin receptor tyrosine kinase inhibitor

Purity: > 98%

 
 
 
 
  

ISCK03 

Cell-permeable, selective SCF/c-Kit inhibitor

Purity: > 99%

 
 
 
 
  

Ki20227 

Potent, selective c-Fms tyrosine kinase inhibitor

Purity: > 95%

 
 
 
 
  

Lestaurtinib 

Potent JAK2, FLT3 and TrkA receptor tyrosine kinase inhibitor

Purity: > 98%

 
 
 
 
  

Momelotinib (CYT387) 

Potent ATP-competitve JAK 1/2 selective inhibitor

Purity: > 95%

 
 
 
 
  

Hydroxy-2-naphthalenylmethylphosphonic acid (HNMPA) 

Insulin receptor tyrosine kinase inhibitor

Purity: > 98%

 
 
 
 
  

Nateglinide 

Insulin secretagog agent. K+ channel blocker

 
 
 
 
  

P1 

EGF receptor binding inhibitor

Purity: > 95%

 
 
 
 
  

PD 174265 

Potent, selective, reversible EGFR tyrosine kinase inhibitor

Purity: > 98%

 
 
 
 

PHA-793887 

Potent CDK2, CDK5 and CDK7 inhibitor

 
 
 
 
  

Quizartinib 

Potent, selective Flt3 inhibitor

Purity: > 99%

 
 
 
 

Razoxane (ICRF-159) 

Potent, cell-permeable, reversible, ATP-competitive PDGF β-receptor inhibitor. Topoisomerase II inhibitor.

Purity: > 98%

 
 
 
 
  

RG-14620 

EGF receptor tyrosine kinase inhibitor

Purity: > 99%

 
 
 
 

Royal jelly acid (10-Hydroxy-2-decenoic acid) 

VEGF inhibitor

Purity: > 98%

 
 
 
 

SSR128129E 

Selective allosteric FGFR inhibitor. Potent antiproliferative agent.

 
 
 
 
  

SU 11274 

Potent, selective cell-permeable Met inhibitor

Purity: > 98%

 
 
 
 
  

SU 6668 

Potent PDGFR inhibitor

Purity: > 98%

 
 
 
 
  

SU 1498 

Selective VEGFR2 inhibitor

Purity: > 99%

 
 
 
 
  

SU4312 

Potent, selective VEGFR and PDGFR receptor tyrosine kinase inhibitor

Purity: > 98%

 
 
 
 
  

SU-5402 

Potent, selective VEGFR and FGFR inhibitor

Purity: > 95%

 
 
 
 
  

SU 5416 (Semaxanib) 

Potent and selective VEGFR inhibitor

Purity: > 99%

 
 
 
 
  

TAK 165 

Potent HER2 tyrosine kinase inhibitor

Purity: > 98%

 
 
 
 
  

Tie2 kinase inhibitor 

Potent, reversible and selective ATP-binding site-targeting Tie2 kinase inhibitor. Cell-permeable.

Purity: > 99%

 
 
 
 
  

Triclosan 

Exhibits antibacterial, antifungal, antiviral, and anti-inflammatory activities.

Purity: > 98%

 
 
 
 
  

Tyrphostin 25 (RG-50875) 

Competitive EGF receptor tyrosine kinase inhibitor

Purity: > 99%

 
 
 
 
  

Tyrphostin 47 

EGFR tyrosine kinase inhibitor

Purity: > 99%

 
 
 
 
  

Tyrphostin 51 

EGFR tyrosine kinase inhibitor

Purity: > 99%

 
 
 
 
  

Tyrphostin 9 

Selective PDGFR tyrosine kinase inhibitor

Purity: > 99%

 
 
 
 
  

Tyrphostin 1 (Tyrphostin A1) 

Inactive tyrphostin

Purity: > 99%

 
 
 
 

(-)-Tyrphostin B44 

Potent EGFR inhibitor

Purity: > 98%

 
 
 
 
  

XL-880 (Foretinib) 

Potent ATP-competitive HGFR and VEGFR2 inhibitor

Purity: > 98%