Cytokines, NF-κB & IκB signaling

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Name

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D,L-1'-Acetoxychavicol acetate 

NF-κB inhibitor

Purity: > 98%

 
 
 
 
  

15-Acetyl-deoxynivalenol (15-ADON) 

Type B trichothecene mycotoxin

Purity: > 98%

 
 
 
 
  

AG-1288 

Non-selective tyrosine kinase inhibitor

Purity: > 98%

 
 
 
 
  

Aloin (Barbaloin) 

Antihistamine, antioxidant and antiproliferation agent

Purity: > 96%

 
 
 
 
  

AMD3100 octahydrochloride 

Highly selective CXCR4 antagonist

Purity: > 99%

 
 
 
 
  

Amlexanox 

Selective TBK1 and IKKε inhibitor

Purity: > 98%

 
 
 
 
  

Asperosaponin VI (Akebia Saponin D) 

Anti-inflammatory, antioxidant agent

Purity: > 98%

 
 
 
 

Astaxanthin 

Potent antioxidant agent. PPARα agonist and PPARγ antagonist.

Purity: > 97%

 
 
 
 
  

Astilbin 

Antioxidant. Anti-inflammatory agent.

Purity: > 98%

 
 
 
 

Avarol 

Potent leukotriene B4 inhibitor. Anti-inflammatory agent.

Purity: > 97%

 
 
 
 
  

BAY 11-7085 

Irreversible inhibitor of TNF-α-induced IxBα phosphorylation

Purity: > 99%

 
 
 
 

BAY 11-7082 

IκBα kinase inhibitor. NF-κB inhibitor. Apoptosis inducer. Inhibits the release of proinflammatory cytokines. Inflammasome inhibitor. Platelet aggregation inhibitor.

Purity: > 99%

 
 
 
 
  

Benzyl isothiocyanate 

Antiproliferative, apoptotic agent

Purity: > 97%

 
 
 
 
  

Benzyl selenocyanate 

Chemopreventive agent

Purity: > 98%

 
 
 
 
  

Bergenin 

Modulates cytokine, IL-1β and TNF-α production

Purity: > 98%

 
 
 
 
  

Bindarit 

CCL2, CCL7 and CCL8 inhibitor. Anti-inflammatory agent.

Purity: > 99%

 
 
 
 
  

Biotinyl-ASTD-FMK 

Competitive EMAP II inhibitor

Purity: > 95%

 
 
 
 
  

Butoconazole nitrate 

Imidazole antifungal agent

Purity: > 99%

 
 
 
 
  

Caffeic acid 

Specific NF-κB inhibitor

Purity: > 98%

 
 
 
 
  

Carnosol 

Anti-oxidant, and anticancer agent

Purity: > 98%

 
 
 
 
  

Celastrol from Celastrus scandens 

Anti-inflammatory and antiproliferative agent

Purity: > 99%

 
 
 
 
  

CHS-828 

NF-κβ inhibitor. Potent antineoplastic agent

Purity: > 98%

 
 
 
 
  

Cordycepin (3-deoxyadenosine) 

Nucleoside antagonist. Inhibits NF-κB signaling

Purity: > 98%

 
 
 
 
  

Diacerein 

Inhibitor of interleukin-1B (IL-1B) production

Purity: > 96%

 
 
 
 
  

Doxifluridine (5'-Deoxy-5-fluorouridine) 

Fluoropyrimidine antitumor and antiangiogenic agent

Purity: > 98%

 
 
 
 
  

Echinacoside 

Caffeic acid glycoside. Antiapoptotic agent.

Purity: > 98%

 
 
 
 
  

Forchlorfenuron (KT-30) 

Synthetic cytokinin and plant growth regulator. Potent septin polymerization inducer.

Purity: > 98%

 
 
 
 
  

Gliotoxin 

Specific NF-κB inhibitor

Purity: > 98%

 
 
 
 
  

Hexamethylene bisacetamide (HMBA) 

Cell differentiation inducer

Purity: > 98%

 
 
 
 
  

Honokiol 

Anti-inflammatory and chemotherapeutic agent

Purity: > 98%

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20-Hydroxyecdysone (Ecdysterone) 

Steroid invertebrate hormone. Antioxidant and apoptotic agent.

Purity: > 98%

 
 
 
 
  

4-Hydroxynonenal 

Lipid peroxidation marker

Purity: > 98%

 
Specific publication references
 
 
 
  

17α-Hydroxyprogesterone caproate (17-OHP) 

Anti-estrogen with anticancer and anti-inflammatory properties.

Purity: > 98%

 
 
 
 
  

IKK-e Kinase Inhibitor II 

Inhibitor of IκB kinases (IKK)

Purity: > 97%

 
 
 
 
  

ISCK03 

Cell permeable, selective SCF/c-Kit inhibitor

Purity: > 99%

 
 
 
 
  

(R,S)-Lenalidomide 

Thalidomide analog, TNF-α inhibitor

Purity: > 98%

 
 
 
 
  

Luteolin 

Antioxidant, anti-inflammatory, anticancer flavonoid

Purity: > 99%

 
 
 
 

Muristerone A 

Ecdysone receptor (EcR) agonist. Ecdysone analog.

Purity: > 95%

 
 
 
 

Nargenicin A1 

Broad spectrum antibiotic agent. Potential anti-inflammatory agent.

Purity: > 98%

 
 
 
 
  

Notoginsenoside R1 

Phytoestrogen, inhibits TNF-α-induced PAI-1

Purity: > 98%

 
 
 
 
  

Olsalazine sodium 

Anti-inflammatory agent

Purity: > 98%

 
 
 
 
  

PDTC (Ammonium pyrrolidinedithiocarbamate) 

Selective NF-κB inhibitor; antioxidant

 
 
 
 
  

Peiminine 

Anti-inflammatory agent

Purity: > 98%

 
 
 
 
  

Pentoxifylline 

Phosphodiesterase inhibitor. Cytokine inhibitor.

Purity: > 99%

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Pimecrolimus (SDZ ASM 981) 

Non-steroidal anti-inflammatory cytokine inhibitor; cell-selective

Purity: > 98%

 
 
 
 
  

Polydatin 

Anti-inflammatory

Purity: > 97%

 
 
 
 
  

QNZ 

Potent, selective NF-kB inhibitor

Purity: > 98%

 
 
 
 
  

Ro 106-9920 

NF-κB inhibitor. Anti-inflammatory agent.

Purity: > 95%

 
 
 
 
  

Ro 106-9920 control 

Control for cell-permeable NF-κB inhibitor Ro 106-9920

Purity: > 99%

 
 
 
 
  

Saikosaponin A 

Saikosaponin D epimer

Purity: > 98%

 
 
 
 
  

Saikosaponin D 

Glucocorticoid receptor agonist. COX-2 and iNOS inhibitor.

Purity: > 98%

 
 
 
 
  

Salsalate 

NSAID. AMPK activator.

Purity: > 95%

 
 
 
 
  

Schisantherin A 

Hepatoprotective, antitumor and antioxidant agent

Purity: > 98%

 
 
 
 
  

Senegenin (Tenuigenin) 

Anti-infammatory agent

Purity: > 98%

 
 
 
 
  

Sodium salicylate 

Cell-permeable anti-inflammatory agent

Purity: > 99%

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Streptochlorin 

Potent antiangiogenic agent

Purity: > 95%

 
 
 
 
  

Tetrandrine 

Calcium channel blocker. Anti-inflammatory and antitumor agent.

Purity: > 98%

 
 
 
 
  

Tiliroside 

Reversible, competitive CYP inhibitor. Anti-inflammatory and antioxidant agent.

Purity: > 98%

 
 
 
 
  

Tranilast 

Anti-inflammatory agent

Purity: > 99%

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Triptolide from Tripterygium wilfordii 

Anti-inflammatory agent with multiple biological activities

Purity: > 99%

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Ursolic acid 

Pentacyclic triterpenoid; antitumourigenic.

Purity: > 99%

 
 
 
 
  

Verbascoside 

PKC inhibitor. NF-κB inhibitor.

Purity: > 98%

 
 
 
 
  

Yangonin 

Potent NF-κβ inhibitor. Selective CB1 agonist. Antioxidant.

Purity: > 98%

 
 
 
 
  

Zerumbone 

Potent NF-κB inhibitor. Anticancer agent.

Purity: > 96%

 
 
 
 

Z-VRPR-FMK (Z-Val-Arg-Pro-DL-Arg-FMK, MALT1 inhibitor) 

Selective, cell-permeable and irreversible MALT1 inhibitor

Purity: > 90%