Your browser does not have JavaScript enabled and some parts of this website will not work without it.

Country selection

Call (888) 77-ABCAM (22226) or contact us

Need help? Contact us

Sign in or Register with us

Welcome

Sign in or

Don't have an account?

Register with us

Products

By product type

Primary antibodies

Secondary antibodies

ELISA, Matched Antibody Pairs and Multiplex Immunoassays

Cell and tissue imaging tools

Cellular and biochemical assays

By product type

Proteins and Peptides

Proteomics tools

Agonists, activators, antagonists and inhibitors

Lysates

Multiplex miRNA assays

By research area

Cancer

Cardiovascular

Cell Biology

Epigenetics

Metabolism

Developmental Biology

By research area

Immunology

Microbiology

Neuroscience

Signal Transduction

Stem Cells
Partnerships

Partner with us

Clinical success doesn’t happen in isolation. Get access to the best antibodies, discovery platforms, and know-how to advance your diagnostic and therapeutic programs.

Find out more
Support
- Protocols & troubleshooting
- Technical FAQs
- Get technical help
- RabMAb Advantages
- Buying FAQs
- Antibody Guide
- Scientific webinars
- Biochemical product FAQ
- Support resources
Check out our protocols

Visit protocols and troubleshooting or check them out using the Abcam app for iPhone

Protocols and troubleshooting

iPhone app
Events
- Conference calendar
- Cancer
- Cardiovascular
- Epigenetics & Nuclear signaling
- Immunology
- Neuroscience
- Stem cells
- Tradeshows
- Scientific webinars
Keep up to date with the latest events

Full event breakdown with abstracts, speakers, registration and more

View global event calendar
Pathways

Cell signalling pathways

View all pathways

View all interactive pathways

Research Area
- + Addiction
- - + Cannabinoid
  - - + CB₁
    - - Agonists
      - Antagonists / inverse agonists
    - CB₂
    - GPR18
    - GPR55
    - Non-selective
    - Other
    - Transporters
  - + Glutamate
  - - + AMPA & Kainate
    - + Broad spectrum / non-selective
    - - Agonists
      - Antagonists
    - + mGlu
    - - General
      - + Group I
      - Agonists
        
        Antagonists
        
        Modulators
      - + Group I & II
      - Agonists
        
        Antagonists
      - + Group II
      - Agonists
        
        Antagonists
      - + Group III
      - Agonists
        
        Allosteric modulators
        
        Antagonists
    - + NMDA
    - - AP-2 binding site
      - + Glutamate Site
      - Agonists
        
        Antagonists
      - + Glycine Site
      - Agonists
        
        Antagonists
      - Ion Channel Site
      - + Polyamine Site
      - Agonists
        
        Antagonists
        
        Other
    - + Transporters
    - - Inhibitors
      - Modulators
  - + Nicotinic
  - - α3
    - α4β2
    - + α7
    - - Agonists
      - Antagonists
    - + General
    - - Agonists
      - Antagonists
  - + Opioids
  - - δ
    - + κ
    - - Agonists
      - Antagonists
    - General
    - ORL₁
    - + µ
    - - Agonists
      - Antagonists
- - Alzheimer's Disease
- - + Apoptosis & cell cycle
  - - Caspase
    - Cyclin-dependent kinase
    - + Growth factors
    - - EGFR
      - FGFR
      - PDGFR
      - VEGFR
    - Other
    - p53
  - Cytoskeleton & motor proteins
  - + Glutamate
  - - + AMPA & Kainate
    - + Broad spectrum / non-selective
    - - Agonists
      - Antagonists
    - + mGlu
    - - General
      - + Group I
      - Agonists
        
        Antagonists
        
        Modulators
      - + Group I & II
      - Agonists
        
        Antagonists
      - + Group II
      - Agonists
        
        Antagonists
      - + Group III
      - Agonists
        
        Allosteric modulators
        
        Antagonists
    - + NMDA
    - - AP-2 binding site
      - + Glutamate Site
      - Agonists
        
        Antagonists
      - + Glycine Site
      - Agonists
        
        Antagonists
      - Ion Channel Site
      - + Polyamine Site
      - Agonists
        
        Antagonists
        
        Other
    - + Transporters
    - - Inhibitors
      - Modulators
  - Immunomodulators
  - + Muscarinic
  - - + M₁
    - - Agonists
      - Antagonists
    - + M₂
    - - Agonists
      - Antagonists
    - M₃
    - + Non-selective
    - - Agonists
      - Antagonists
  - + Nicotinic
  - - α3
    - α4β2
    - + α7
    - - Agonists
      - Antagonists
    - + General
    - - Agonists
      - Antagonists
  - - Nitric oxide signaling
  - - Antioxidants
    - - Donors / precursors
    - - Donors
      - Other
    - NOS
  - + Signaling
  - - Amyloidogenesis
    - + Angiogenesis
    - - Antiangiogenics
      - VEGFR
    - + Apoptosis & cell cycle
    - - Caspase
      - Cyclin-dependent kinase
      - + Growth factors
      - EGFR
        
        FGFR
        
        PDGFR
        
        VEGFR
      - Other
      - p53
    - + Ca²⁺ signaling
    - Cytoskeleton & motor proteins
    - DNA, RNA & protein synthesis
    - + Endocytosis & exocytosis
    - - Clathrin
      - Dynamin
    - Heat Shock Proteins
    - Immunomodulators
    - + Lipid signaling
    - + Signal transduction
    - - Cytokines
      - + Hedgehog signaling
      - Inhibitors
        
        Smoothened
      - + Inositol & cAMP signaling
      - Adenylyl cyclase
        
        cAMP
        
        Inositol lipids
        
        + Protein Kinase A
        
        Activators
        
        Inhibitors
      - JAK/STAT signaling
      - + MAPK
      - General
        
        JNK
        
        MKK/MEK
        
        MNK
        
        p38
        
        Raf kinase
      - NF-κB & IκB signaling
      - + Nitric oxide signaling
      - Antioxidants
        
        + Donors / precursors
        
        Donors
        
        Other
        
        NOS
      - + PI3K/Akt signaling
      - + Akt
        
        Activators
        
        Inhibitors
        
        mTOR
        
        PI3-kinase
      - Transcription factors
      - Wnt signaling
    - Stem Cells
- + Cancer
- - + Angiogenesis
  - + Apoptosis & cell cycle
  - - BCL
    - Caspase
    - Chk
    - Cyclin-dependent kinase
    - + Growth factors
    - - EGFR
      - FGFR
      - Kit
      - PDGFR
      - Trk
      - VEGFR
    - Other
    - + p53
    - - Activators
      - Inhibitors
    - PARP
    - TIE
  - + Ca²⁺ signaling
  - + Cytoskeleton & motor proteins
  - - Actin
    - Inhibitors
    - Kinesin
    - Myosin
    - Other
    - Tubulin
  - + DNA, RNA & protein synthesis
  - + Epigenetics
  - + Extracellular matrix & cell adhesion
  - + Nuclear Receptors
  - + Signal transduction
  - - Cytokines, NF-κB & IκB signaling
    - G-Protein related
    - + Hedgehog signaling
    - + Inositol & cAMP signaling
    - + JAK/STAT
    - - JAK
      - STAT
    - + MAPK
    - - ERK
      - General
      - JNK
      - MKK/MEK
      - MNK
      - p38
      - Raf kinase
    - + Nitric oxide & oxidative stress
    - - Antioxidants
      - + Donors / precursors
      - Donors
        
        Other
      - NOS
      - Other
      - ROS
    - + PI3K/Akt signaling
    - - + Akt
      - Activators
        
        Inhibitors
      - Glycogen synthase kinase
      - mTOR
      - p21
      - PI3-kinase
      - PP1 & PP2A
    - Transcription factors
    - Wnt signaling
- + Depression
- - + Glutamate
  - - + AMPA & Kainate
    - + Broad spectrum / non-selective
    - - Agonists
      - Antagonists
    - + mGlu
    - - General
      - + Group I
      - Agonists
        
        Antagonists
        
        Modulators
      - + Group I & II
      - Agonists
        
        Antagonists
      - + Group II
      - Agonists
        
        Antagonists
      - + Group III
      - Agonists
        
        Allosteric modulators
        
        Antagonists
    - + NMDA
    - - AP-2 binding site
      - + Glutamate Site
      - Agonists
        
        Antagonists
      - + Glycine Site
      - Agonists
        
        Antagonists
      - Ion Channel Site
      - + Polyamine Site
      - Agonists
        
        Antagonists
        
        Other
    - + Transporters
    - - Inhibitors
      - Modulators
  - + Serotonin
  - - + 5-HT₁
    - - 5HT1_F
      - + 5HT_1A
      - Agonists
        
        Antagonists
      - + 5HT_1B
      - Agonists
        
        Antagonists
      - 5HT_1C
      - + 5HT_1D
      - Agonists
        
        Antagonists
    - + 5-HT₂
    - - + 5HT_2A
      - Agonists
        
        Antagonists
      - + 5HT_2B
      - Agonists
        
        Antagonists
      - 5HT_2C
      - + Non-selective
      - Agonists
        
        Antagonists
    - + 5-HT₃
    - - Agonists
      - Antagonists
    - 5-HT₄
    - 5-ht₅
    - + 5-HT₆
    - - Agonists
      - Antagonists
    - + 5-HT₇
    - - Agonists
      - Antagonists
    - + Non-selective
    - - Agonists
      - Antagonists
    - Transporters
- + Diabetes
- - + Apoptosis & cell cycle
  - - Caspase
    - Cyclin-dependent kinase
    - + Growth factors
    - - EGFR
      - FGFR
      - PDGFR
      - VEGFR
    - Other
    - p53
  - + Ca²⁺ signaling
  - Cytoskeleton & motor proteins
  - Immunomodulators
  - + Nitric oxide signaling
  - - Antioxidants
    - + Donors / precursors
    - - Donors
      - Other
    - NOS
  - Other
  - + Potassium
  - - Activators
    - Blockers
  - + Signaling
  - - Amyloidogenesis
    - + Angiogenesis
    - - Antiangiogenics
      - VEGFR
    - + Apoptosis & cell cycle
    - - Caspase
      - Cyclin-dependent kinase
      - + Growth factors
      - EGFR
        
        FGFR
        
        PDGFR
        
        VEGFR
      - Other
      - p53
    - + Ca²⁺ signaling
    - Cytoskeleton & motor proteins
    - DNA, RNA & protein synthesis
    - + Endocytosis & exocytosis
    - - Clathrin
      - Dynamin
    - Heat Shock Proteins
    - Immunomodulators
    - + Lipid signaling
    - + Signal transduction
    - - Cytokines
      - + Hedgehog signaling
      - Inhibitors
        
        Smoothened
      - + Inositol & cAMP signaling
      - Adenylyl cyclase
        
        cAMP
        
        Inositol lipids
        
        + Protein Kinase A
        
        Activators
        
        Inhibitors
      - JAK/STAT signaling
      - + MAPK
      - General
        
        JNK
        
        MKK/MEK
        
        MNK
        
        p38
        
        Raf kinase
      - NF-κB & IκB signaling
      - + Nitric oxide signaling
      - Antioxidants
        
        + Donors / precursors
        
        Donors
        
        Other
        
        NOS
      - + PI3K/Akt signaling
      - + Akt
        
        Activators
        
        Inhibitors
        
        mTOR
        
        PI3-kinase
      - Transcription factors
      - Wnt signaling
    - Stem Cells
  - Sodium
  - + TRP
  - - Agonists
    - Blockers
- + Epigenetics
- - DNA Methyltransferases (DNMTs)
  - Histone Acetyltransferases (HATs)
  - Histone Deacetylases (HDAC)
  - Histone Methyltransferase
  - Other
- + Heart disease
- - + Adenosine
  - - + A₁
    - - Agonists
      - Antagonists
    - + A₂
    - - Agonists
      - Antagonists
    - A₃
    - + Non-selective
    - - Agonists
      - Antagonists
    - Other
  - + Adrenoceptors
  - - + α
    - - + α₁
      - Agonists
        
        Antagonists
      - + α₂
      - Agonists
        
        Antagonists
      - Non-selective
    - + β
    - - + β₁
      - Agonists
        
        Antagonist
      - + β₂
      - Agonists
        
        antagonist
      - β₃
      - + Non-selective
      - Agonist
        
        Agonists
        
        Antagonist
        
        Antagonist
    - Non-selective
    - Transporters
  - + Apoptosis & cell cycle
  - - Caspase
    - Cyclin-dependent kinase
    - + Growth factors
    - - EGFR
      - FGFR
      - PDGFR
      - VEGFR
    - Other
    - p53
  - + Ca²⁺ signaling
  - - Ca_v channels
    - Ca²⁺-ATPase
    - CAM Kinase
    - Chelators
    - General
    - Ionophores, Indicators & Chelators
    - IP₃ & ryanodine receptors
    - Na⁺/Ca²⁺ exchange
  - Calcium
  - Cytoskeleton & motor proteins
  - Immunomodulators
  - + Nitric oxide signaling
  - - Antioxidants
    - + Donors / precursors
    - - Donors
      - Other
    - NOS
  - + Nuclear Receptors
  - - + Estrogen
    - - Agonists
      - Antagonists
    - Glucocorticoid
    - Mineralocorticoid
    - PPAR
    - Progesterone
    - Retinoic acid receptors
    - Retinoid X receptors
  - Other
  - + Potassium
  - - Activators
    - Blockers
  - + Signaling
  - - Amyloidogenesis
    - + Angiogenesis
    - - Antiangiogenics
      - VEGFR
    - + Apoptosis & cell cycle
    - - Caspase
      - Other
    - + Ca²⁺ signaling
    - - Ca_v channels
      - Ca²⁺-ATPase
      - Chelators
      - General
      - Ionophores
      - IP₃ & ryanodine receptors
      - Na⁺/Ca²⁺ exchange
    - Coenzymes
    - + Cytokine and NF-κB signaling
    - - Cytokines
      - NF-κB & IκB
      - Other
      - STAT
    - Cytoskeleton & motor proteins
    - DNA, RNA & protein synthesis
    - + Endocytosis & exocytosis
    - - Clathrin
      - Dynamin
    - Heat Shock Proteins
    - Hedgehog signaling
    - Immunomodulators
    - + Inositol & cAMP signaling
    - - Adenylyl cyclase
      - cAMP
      - Inositol lipids
      - + Protein Kinase A
      - Activators
        
        Inhibitors
    - + Lipid signaling
    - - Cyclooxygenase
      - HMG-CoA reductase
      - Inhibitors
      - Oxygenase
      - Phospholipase & Lipase
      - PI3-kinase
    - + Nitric Oxide
    - - Antioxidants
      - + Donors / precursors
      - Donors
        
        Other
      - NOS
    - Stem Cells
  - Sodium
  - + TRP
  - - Agonists
    - Blockers
- + Hypertension
- - + Adrenoceptors
  - - + α
    - - + α₁
      - Agonists
        
        Antagonists
      - + α₂
      - Agonists
        
        Antagonists
      - Non-selective
    - + β
    - - + β₁
      - Agonists
        
        Antagonist
      - + β₂
      - Agonists
        
        antagonist
      - β₃
      - + Non-selective
      - Agonist
        
        Agonists
        
        Antagonist
        
        Antagonist
    - Non-selective
    - Transporters
  - + Apoptosis & cell cycle
  - - Caspase
    - Cyclin-dependent kinase
    - + Growth factors
    - - EGFR
      - FGFR
      - PDGFR
      - VEGFR
    - Other
    - p53
  - + Ca²⁺ signaling
  - - Ca_v channels
    - Ca²⁺-ATPase
    - CAM Kinase
    - Chelators
    - General
    - Ionophores, Indicators & Chelators
    - IP₃ & ryanodine receptors
    - Na⁺/Ca²⁺ exchange
  - Cytoskeleton & motor proteins
  - Immunomodulators
  - + Nitric oxide signaling
  - - Antioxidants
    - + Donors / precursors
    - - Donors
      - Other
    - NOS
  - + Nuclear Receptors
  - - + Estrogen
    - - Agonists
      - Antagonists
    - Glucocorticoid
    - Mineralocorticoid
    - PPAR
    - Progesterone
    - Retinoic acid receptors
    - Retinoid X receptors
  - Other
  - + Peptide Receptors
  - - + Angiotensin
    - - Agonists
      - Antagonists
    - AXOR
    - Bradykinin
    - CCK
    - Endothelin
    - Galanin
    - + Ghrelin
    - - Agonists
      - Antagonists
    - Glucagon
    - LHRH
    - Melanocyte Stimulating Hormone
    - Neuropeptide S
    - Neuropeptide Y
    - Orexin
    - Other
    - Oxytocin
    - PAR
    - Sensory Neuron Specific Receptor
    - Substance P
    - Tachykinins
    - Vasopressin
    - VIP
  - + Potassium
  - - Activators
    - Blockers
  - + Signaling
  - - Amyloidogenesis
    - + Angiogenesis
    - - Antiangiogenics
      - VEGFR
    - + Apoptosis & cell cycle
    - - Caspase
      - Cyclin-dependent kinase
      - + Growth factors
      - EGFR
        
        FGFR
        
        PDGFR
        
        VEGFR
      - Other
      - p53
    - + Ca²⁺ signaling
    - Cytoskeleton & motor proteins
    - DNA, RNA & protein synthesis
    - + Endocytosis & exocytosis
    - - Clathrin
      - Dynamin
    - Heat Shock Proteins
    - Immunomodulators
    - + Lipid signaling
    - + Signal transduction
    - - Cytokines
      - + Hedgehog signaling
      - Inhibitors
        
        Smoothened
      - + Inositol & cAMP signaling
      - Adenylyl cyclase
        
        cAMP
        
        Inositol lipids
        
        + Protein Kinase A
        
        Activators
        
        Inhibitors
      - JAK/STAT signaling
      - + MAPK
      - General
        
        JNK
        
        MKK/MEK
        
        MNK
        
        p38
        
        Raf kinase
      - NF-κB & IκB signaling
      - + Nitric oxide signaling
      - Antioxidants
        
        + Donors / precursors
        
        Donors
        
        Other
        
        NOS
      - + PI3K/Akt signaling
      - + Akt
        
        Activators
        
        Inhibitors
        
        mTOR
        
        PI3-kinase
      - Transcription factors
      - Wnt signaling
    - Stem Cells
  - Sodium
  - + TRP
  - - Agonists
    - Blockers
- + Obesity
- - + Apoptosis & cell cycle
  - - Caspase
    - Cyclin-dependent kinase
    - + Growth factors
    - - EGFR
      - FGFR
      - PDGFR
      - VEGFR
    - Other
    - p53
  - + Ca²⁺ signaling
  - - Ca_v channels
    - Ca²⁺-ATPase
    - CAM Kinase
    - Chelators
    - General
    - Ionophores, Indicators & Chelators
    - IP₃ & ryanodine receptors
    - Na⁺/Ca²⁺ exchange
  - + Cannabinoid
  - - + CB₁
    - - Agonists
      - Antagonists / inverse agonists
    - CB₂
    - GPR18
    - GPR55
    - Non-selective
    - Other
    - Transporters
  - Cytoskeleton & motor proteins
  - Immunomodulators
  - + Muscarinic
  - - + M₁
    - - Agonists
      - Antagonists
    - + M₂
    - - Agonists
      - Antagonists
    - M₃
    - + Non-selective
    - - Agonists
      - Antagonists
  - + Nitric oxide signaling
  - - Antioxidants
    - + Donors / precursors
    - - Donors
      - Other
    - NOS
  - Other
  - + Peptide Receptors
  - - + Angiotensin
    - - Agonists
      - Antagonists
    - AXOR
    - Bradykinin
    - CCK
    - Endothelin
    - Galanin
    - + Ghrelin
    - - Agonists
      - Antagonists
    - Glucagon
    - LHRH
    - Melanocyte Stimulating Hormone
    - Neuropeptide S
    - Neuropeptide Y
    - Orexin
    - Other
    - Oxytocin
    - PAR
    - Sensory Neuron Specific Receptor
    - Substance P
    - Tachykinins
    - Vasopressin
    - VIP
  - + Potassium
  - - Activators
    - Blockers
  - + Serotonin
  - - + 5-HT₁
    - - 5HT1_F
      - + 5HT_1A
      - Agonists
        
        Antagonists
      - + 5HT_1B
      - Agonists
        
        Antagonists
      - 5HT_1C
      - + 5HT_1D
      - Agonists
        
        Antagonists
    - + 5-HT₂
    - - + 5HT_2A
      - Agonists
        
        Antagonists
      - + 5HT_2B
      - Agonists
        
        Antagonists
      - 5HT_2C
      - + Non-selective
      - Agonists
        
        Antagonists
    - + 5-HT₃
    - - Agonists
      - Antagonists
    - 5-HT₄
    - 5-ht₅
    - + 5-HT₆
    - - Agonists
      - Antagonists
    - + 5-HT₇
    - - Agonists
      - Antagonists
    - + Non-selective
    - - Agonists
      - Antagonists
    - Transporters
  - + Signaling
  - - Amyloidogenesis
    - + Angiogenesis
    - - Antiangiogenics
      - VEGFR
    - + Apoptosis & cell cycle
    - - Caspase
      - Cyclin-dependent kinase
      - + Growth factors
      - EGFR
        
        FGFR
        
        PDGFR
        
        VEGFR
      - Other
      - p53
    - + Ca²⁺ signaling
    - Cytoskeleton & motor proteins
    - DNA, RNA & protein synthesis
    - + Endocytosis & exocytosis
    - - Clathrin
      - Dynamin
    - Heat Shock Proteins
    - Immunomodulators
    - + Lipid signaling
    - + Signal transduction
    - - Cytokines
      - + Hedgehog signaling
      - Inhibitors
        
        Smoothened
      - + Inositol & cAMP signaling
      - Adenylyl cyclase
        
        cAMP
        
        Inositol lipids
        
        + Protein Kinase A
        
        Activators
        
        Inhibitors
      - JAK/STAT signaling
      - + MAPK
      - General
        
        JNK
        
        MKK/MEK
        
        MNK
        
        p38
        
        Raf kinase
      - NF-κB & IκB signaling
      - + Nitric oxide signaling
      - Antioxidants
        
        + Donors / precursors
        
        Donors
        
        Other
        
        NOS
      - + PI3K/Akt signaling
      - + Akt
        
        Activators
        
        Inhibitors
        
        mTOR
        
        PI3-kinase
      - Transcription factors
      - Wnt signaling
    - Stem Cells
  - Sodium
  - + TRP
  - - Agonists
    - Blockers
- + Pain & inflammation
- - + Apoptosis & cell cycle
  - - Caspase
    - Cyclin-dependent kinase
    - + Growth factors
    - - EGFR
      - FGFR
      - PDGFR
      - VEGFR
    - Other
    - p53
  - + Ca²⁺ signaling
  - - Ca_v channels
    - Ca²⁺-ATPase
    - CAM Kinase
    - Chelators
    - General
    - Ionophores, Indicators & Chelators
    - IP₃ & ryanodine receptors
    - Na⁺/Ca²⁺ exchange
  - + Cannabinoid
  - - + CB₁
    - - Agonists
      - Antagonists / inverse agonists
    - CB₂
    - GPR18
    - GPR55
    - Non-selective
    - Other
    - Transporters
  - Cytoskeleton & motor proteins
  - + GABA
  - - + GABA_A
    - + GABA_B
    - + Non-selective
    - - Agonists
      - Antagonists
    - Other
    - Transporters
  - + Glutamate
  - - + AMPA & Kainate
    - + Broad spectrum / non-selective
    - - Agonists
      - Antagonists
    - + mGlu
    - - General
      - + Group I
      - Agonists
        
        Antagonists
        
        Modulators
      - + Group I & II
      - Agonists
        
        Antagonists
      - + Group II
      - Agonists
        
        Antagonists
      - + Group III
      - Agonists
        
        Allosteric modulators
        
        Antagonists
    - + NMDA
    - - AP-2 binding site
      - + Glutamate Site
      - Agonists
        
        Antagonists
      - + Glycine Site
      - Agonists
        
        Antagonists
      - Ion Channel Site
      - + Polyamine Site
      - Agonists
        
        Antagonists
        
        Other
    - + Transporters
    - - Inhibitors
      - Modulators
  - + Histamine
  - - + H₁
    - - Agonists
      - Antagonists
    - + H₂
    - - Agonists
      - Antagonists
    - + H₃
    - - Agonists
      - Antagonists
    - + H₄
    - - Agonists
      - Antagonists
    - Non-selective
  - Immunomodulators
  - + Nitric oxide signaling
  - - Antioxidants
    - + Donors / precursors
    - - Donors
      - Other
    - NOS
  - + Opioids
  - - δ
    - + κ
    - - Agonists
      - Antagonists
    - General
    - ORL₁
    - + µ
    - - Agonists
      - Antagonists
  - Other
  - + Peptide Receptors
  - - + Angiotensin
    - - Agonists
      - Antagonists
    - AXOR
    - Bradykinin
    - CCK
    - Endothelin
    - Galanin
    - + Ghrelin
    - - Agonists
      - Antagonists
    - Glucagon
    - LHRH
    - Melanocyte Stimulating Hormone
    - Neuropeptide S
    - Neuropeptide Y
    - Orexin
    - Other
    - Oxytocin
    - PAR
    - Sensory Neuron Specific Receptor
    - Substance P
    - Tachykinins
    - Vasopressin
    - VIP
  - + Potassium
  - - Activators
    - Blockers
  - + Signaling
  - - Amyloidogenesis
    - + Angiogenesis
    - - Antiangiogenics
      - VEGFR
    - + Apoptosis & cell cycle
    - - Caspase
      - Other
    - + Ca²⁺ signaling
    - - Ca_v channels
      - Ca²⁺-ATPase
      - Chelators
      - General
      - Ionophores
      - IP₃ & ryanodine receptors
      - Na⁺/Ca²⁺ exchange
    - Coenzymes
    - + Cytokine and NF-κB signaling
    - - Cytokines
      - NF-κB & IκB
      - Other
      - STAT
    - Cytoskeleton & motor proteins
    - DNA, RNA & protein synthesis
    - + Endocytosis & exocytosis
    - - Clathrin
      - Dynamin
    - Heat Shock Proteins
    - Hedgehog signaling
    - Immunomodulators
    - + Inositol & cAMP signaling
    - - Adenylyl cyclase
      - cAMP
      - Inositol lipids
      - + Protein Kinase A
      - Activators
        
        Inhibitors
    - + Lipid signaling
    - - Cyclooxygenase
      - HMG-CoA reductase
      - Inhibitors
      - Oxygenase
      - Phospholipase & Lipase
      - PI3-kinase
    - + Nitric Oxide
    - - Antioxidants
      - + Donors / precursors
      - Donors
        
        Other
      - NOS
    - Stem Cells
  - Sodium
  - + TRP
  - - Agonists
    - Blockers
- + Parkinson's Disease
- - + Adrenoceptors
  - - + α
    - - + α₁
      - Agonists
        
        Antagonists
      - + α₂
      - Agonists
        
        Antagonists
      - Non-selective
    - + β
    - - + β₁
      - Agonists
        
        Antagonist
      - + β₂
      - Agonists
        
        antagonist
      - β₃
      - + Non-selective
      - Agonist
        
        Agonists
        
        Antagonist
        
        Antagonist
    - Non-selective
    - Transporters
  - + Dopamine
  - - + D₁
    - - Agonists
      - Antagonists
    - + D₂
    - - Agonists
      - Antagonists
    - + D₃
    - - Agonists
      - Antagonists
    - + D₄
    - - Agonists
      - Antagonists
    - + D₅
    - - Agonists
      - Antagonists
    - + Non-selective
    - - Agonists
      - Antagonists
    - Other
    - Transporters
  - + Glutamate
  - - + AMPA & Kainate
    - + Broad spectrum / non-selective
    - - Agonists
      - Antagonists
    - + mGlu
    - - General
      - + Group I
      - Agonists
        
        Antagonists
        
        Modulators
      - + Group I & II
      - Agonists
        
        Antagonists
      - + Group II
      - Agonists
        
        Antagonists
      - + Group III
      - Agonists
        
        Allosteric modulators
        
        Antagonists
    - + NMDA
    - - AP-2 binding site
      - + Glutamate Site
      - Agonists
        
        Antagonists
      - + Glycine Site
      - Agonists
        
        Antagonists
      - Ion Channel Site
      - + Polyamine Site
      - Agonists
        
        Antagonists
        
        Other
    - + Transporters
    - - Inhibitors
      - Modulators
  - + Nicotinic
  - - α3
    - α4β2
    - + α7
    - - Agonists
      - Antagonists
    - + General
    - - Agonists
      - Antagonists
  - + Serotonin
  - - + 5-HT₁
    - - 5HT1_F
      - + 5HT_1A
      - Agonists
        
        Antagonists
      - + 5HT_1B
      - Agonists
        
        Antagonists
      - 5HT_1C
      - + 5HT_1D
      - Agonists
        
        Antagonists
    - + 5-HT₂
    - - + 5HT_2A
      - Agonists
        
        Antagonists
      - + 5HT_2B
      - Agonists
        
        Antagonists
      - 5HT_2C
      - + Non-selective
      - Agonists
        
        Antagonists
    - + 5-HT₃
    - - Agonists
      - Antagonists
    - 5-HT₄
    - 5-ht₅
    - + 5-HT₆
    - - Agonists
      - Antagonists
    - + 5-HT₇
    - - Agonists
      - Antagonists
    - + Non-selective
    - - Agonists
      - Antagonists
    - Transporters
- + Respiratory disease
- - + Adenosine
  - - + A₁
    - - Agonists
      - Antagonists
    - + A₂
    - - Agonists
      - Antagonists
    - A₃
    - + Non-selective
    - - Agonists
      - Antagonists
    - Other
  - + Adrenoceptors
  - - + α
    - - + α₁
      - Agonists
        
        Antagonists
      - + α₂
      - Agonists
        
        Antagonists
      - Non-selective
    - + β
    - - + β₁
      - Agonists
        
        Antagonist
      - + β₂
      - Agonists
        
        antagonist
      - β₃
      - + Non-selective
      - Agonist
        
        Agonists
        
        Antagonist
        
        Antagonist
    - Non-selective
    - Transporters
  - + Apoptosis & cell cycle
  - - Caspase
    - Cyclin-dependent kinase
    - + Growth factors
    - - EGFR
      - FGFR
      - PDGFR
      - VEGFR
    - Other
    - p53
  - + Ca²⁺ signaling
  - - Ca_v channels
    - Ca²⁺-ATPase
    - CAM Kinase
    - Chelators
    - General
    - Ionophores, Indicators & Chelators
    - IP₃ & ryanodine receptors
    - Na⁺/Ca²⁺ exchange
  - Cytoskeleton & motor proteins
  - + Histamine
  - - + H₁
    - - Agonists
      - Antagonists
    - + H₂
    - - Agonists
      - Antagonists
    - + H₃
    - - Agonists
      - Antagonists
    - + H₄
    - - Agonists
      - Antagonists
    - Non-selective
  - Immunomodulators
  - + Muscarinic
  - - + M₁
    - - Agonists
      - Antagonists
    - + M₂
    - - Agonists
      - Antagonists
    - M₃
    - + Non-selective
    - - Agonists
      - Antagonists
  - + Nitric oxide signaling
  - - Antioxidants
    - + Donors / precursors
    - - Donors
      - Other
    - NOS
  - Other
  - + Peptide Receptors
  - - + Angiotensin
    - - Agonists
      - Antagonists
    - AXOR
    - Bradykinin
    - CCK
    - Endothelin
    - Galanin
    - + Ghrelin
    - - Agonists
      - Antagonists
    - Glucagon
    - LHRH
    - Melanocyte Stimulating Hormone
    - Neuropeptide S
    - Neuropeptide Y
    - Orexin
    - Other
    - Oxytocin
    - PAR
    - Sensory Neuron Specific Receptor
    - Substance P
    - Tachykinins
    - Vasopressin
    - VIP
  - + Potassium
  - - Activators
    - Blockers
  - + Signaling
  - - Amyloidogenesis
    - + Angiogenesis
    - - Antiangiogenics
      - VEGFR
    - + Apoptosis & cell cycle
    - - Caspase
      - Other
    - + Ca²⁺ signaling
    - - Ca_v channels
      - Ca²⁺-ATPase
      - Chelators
      - General
      - Ionophores
      - IP₃ & ryanodine receptors
      - Na⁺/Ca²⁺ exchange
    - Coenzymes
    - + Cytokine and NF-κB signaling
    - - Cytokines
      - NF-κB & IκB
      - Other
      - STAT
    - Cytoskeleton & motor proteins
    - DNA, RNA & protein synthesis
    - + Endocytosis & exocytosis
    - - Clathrin
      - Dynamin
    - Heat Shock Proteins
    - Hedgehog signaling
    - Immunomodulators
    - + Inositol & cAMP signaling
    - - Adenylyl cyclase
      - cAMP
      - Inositol lipids
      - + Protein Kinase A
      - Activators
        
        Inhibitors
    - + Lipid signaling
    - - Cyclooxygenase
      - HMG-CoA reductase
      - Inhibitors
      - Oxygenase
      - Phospholipase & Lipase
      - PI3-kinase
    - + Nitric Oxide
    - - Antioxidants
      - + Donors / precursors
      - Donors
        
        Other
      - NOS
    - Stem Cells
  - Sodium
  - + TRP
  - - Agonists
    - Blockers
- + Schizophrenia
- - + Adrenoceptors
  - - + α
    - - + α₁
      - Agonists
        
        Antagonists
      - + α₂
      - Agonists
        
        Antagonists
      - Non-selective
    - + β
    - - + β₁
      - Agonists
        
        Antagonist
      - + β₂
      - Agonists
        
        antagonist
      - β₃
      - + Non-selective
      - Agonist
        
        Agonists
        
        Antagonist
        
        Antagonist
    - Non-selective
    - Transporters
  - + Dopamine
  - - + D₁
    - - Agonists
      - Antagonists
    - + D₂
    - - Agonists
      - Antagonists
    - + D₃
    - - Agonists
      - Antagonists
    - + D₄
    - - Agonists
      - Antagonists
    - + D₅
    - - Agonists
      - Antagonists
    - + Non-selective
    - - Agonists
      - Antagonists
    - Other
    - Transporters
  - + GABA
  - - + GABA_A
    - + GABA_B
    - + Non-selective
    - - Agonists
      - Antagonists
    - Other
    - Transporters
  - + Glutamate
  - - + AMPA & Kainate
    - + Broad spectrum / non-selective
    - - Agonists
      - Antagonists
    - + mGlu
    - - General
      - + Group I
      - Agonists
        
        Antagonists
        
        Modulators
      - + Group I & II
      - Agonists
        
        Antagonists
      - + Group II
      - Agonists
        
        Antagonists
      - + Group III
      - Agonists
        
        Allosteric modulators
        
        Antagonists
    - + NMDA
    - - AP-2 binding site
      - + Glutamate Site
      - Agonists
        
        Antagonists
      - + Glycine Site
      - Agonists
        
        Antagonists
      - Ion Channel Site
      - + Polyamine Site
      - Agonists
        
        Antagonists
        
        Other
    - + Transporters
    - - Inhibitors
      - Modulators
  - + Muscarinic
  - - + M₁
    - - Agonists
      - Antagonists
    - + M₂
    - - Agonists
      - Antagonists
    - M₃
    - + Non-selective
    - - Agonists
      - Antagonists
  - + Nicotinic
  - - α3
    - α4β2
    - + α7
    - - Agonists
      - Antagonists
    - + General
    - - Agonists
      - Antagonists
  - + Serotonin
  - - + 5-HT₁
    - - 5HT1_F
      - + 5HT_1A
      - Agonists
        
        Antagonists
      - + 5HT_1B
      - Agonists
        
        Antagonists
      - 5HT_1C
      - + 5HT_1D
      - Agonists
        
        Antagonists
    - + 5-HT₂
    - - + 5HT_2A
      - Agonists
        
        Antagonists
      - + 5HT_2B
      - Agonists
        
        Antagonists
      - 5HT_2C
      - + Non-selective
      - Agonists
        
        Antagonists
    - + 5-HT₃
    - - Agonists
      - Antagonists
    - 5-HT₄
    - 5-ht₅
    - + 5-HT₆
    - - Agonists
      - Antagonists
    - + 5-HT₇
    - - Agonists
      - Antagonists
    - + Non-selective
    - - Agonists
      - Antagonists
    - Transporters
- + Stem Cells
- - Growth factors
  - Hedgehog signaling
  - JAK/STAT
  - Other
  - Wnt signaling
- + Stress / Anxiety
- - + Adrenoceptors
  - - + α
    - - + α₁
      - Agonists
        
        Antagonists
      - + α₂
      - Agonists
        
        Antagonists
      - Non-selective
    - + β
    - - + β₁
      - Agonists
        
        Antagonist
      - + β₂
      - Agonists
        
        antagonist
      - β₃
      - + Non-selective
      - Agonist
        
        Agonists
        
        Antagonist
        
        Antagonist
    - Non-selective
    - Transporters
  - + Dopamine
  - - + D₁
    - - Agonists
      - Antagonists
    - + D₂
    - - Agonists
      - Antagonists
    - + D₃
    - - Agonists
      - Antagonists
    - + D₄
    - - Agonists
      - Antagonists
    - + D₅
    - - Agonists
      - Antagonists
    - + Non-selective
    - - Agonists
      - Antagonists
    - Other
    - Transporters
  - + GABA
  - - + GABA_A
    - + GABA_B
    - + Non-selective
    - - Agonists
      - Antagonists
    - Other
    - Transporters
  - + Serotonin
  - - + 5-HT₁
    - - 5HT1_F
      - + 5HT_1A
      - Agonists
        
        Antagonists
      - + 5HT_1B
      - Agonists
        
        Antagonists
      - 5HT_1C
      - + 5HT_1D
      - Agonists
        
        Antagonists
    - + 5-HT₂
    - - + 5HT_2A
      - Agonists
        
        Antagonists
      - + 5HT_2B
      - Agonists
        
        Antagonists
      - 5HT_2C
      - + Non-selective
      - Agonists
        
        Antagonists
    - + 5-HT₃
    - - Agonists
      - Antagonists
    - 5-HT₄
    - 5-HT₅
    - + 5-HT₆
    - - Agonists
      - Antagonists
    - + 5-HT₇
    - - Agonists
      - Antagonists
    - + Non-selective
    - - Agonists
      - Antagonists
    - Transporters
- + Stroke
- - + Adenosine
  - - + A₁
    - - Agonists
      - Antagonists
    - + A₂
    - - Agonists
      - Antagonists
    - A₃
    - + Non-selective
    - - Agonists
      - Antagonists
    - Other
  - + Apoptosis & cell cycle
  - - Caspase
    - Cyclin-dependent kinase
    - + Growth factors
    - - EGFR
      - FGFR
      - PDGFR
      - VEGFR
    - Other
    - p53
  - + Ca²⁺ signaling
  - - Ca_v channels
    - Ca²⁺-ATPase
    - CAM Kinase
    - Chelators
    - General
    - Ionophores, Indicators & Chelators
    - IP₃ & ryanodine receptors
    - Na⁺/Ca²⁺ exchange
  - Cytoskeleton & motor proteins
  - + Glutamate
  - - + AMPA & Kainate
    - + Broad spectrum / non-selective
    - - Agonists
      - Antagonists
    - + mGlu
    - - General
      - + Group I
      - Agonists
        
        Antagonists
        
        Modulators
      - + Group I & II
      - Agonists
        
        Antagonists
      - + Group II
      - Agonists
        
        Antagonists
      - + Group III
      - Agonists
        
        Allosteric modulators
        
        Antagonists
    - + NMDA
    - - AP-2 binding site
      - + Glutamate Site
      - Agonists
        
        Antagonists
      - + Glycine Site
      - Agonists
        
        Antagonists
      - Ion Channel Site
      - + Polyamine Site
      - Agonists
        
        Antagonists
        
        Other
    - + Transporters
    - - Inhibitors
      - Modulators
  - Immunomodulators
  - + Nitric oxide signaling
  - - Antioxidants
    - + Donors / precursors
    - - Donors
      - Other
    - NOS
  - + Nuclear Receptors
  - - + Estrogen
    - - Agonists
      - Antagonists
    - Glucocorticoid
    - Mineralocorticoid
    - PPAR
    - Progesterone
    - Retinoic acid receptors
    - Retinoid X receptors
  - Other
  - + Potassium
  - - Activators
    - Blockers
  - + Signaling
  - - Amyloidogenesis
    - + Angiogenesis
    - - Antiangiogenics
      - VEGFR
    - + Apoptosis & cell cycle
    - - Caspase
      - Cyclin-dependent kinase
      - + Growth factors
      - EGFR
        
        FGFR
        
        PDGFR
        
        VEGFR
      - Other
      - p53
    - + Ca²⁺ signaling
    - Cytoskeleton & motor proteins
    - DNA, RNA & protein synthesis
    - + Endocytosis & exocytosis
    - - Clathrin
      - Dynamin
    - Heat Shock Proteins
    - Immunomodulators
    - + Lipid signaling
    - + Signal transduction
    - - Cytokines
      - + Hedgehog signaling
      - Inhibitors
        
        Smoothened
      - + Inositol & cAMP signaling
      - Adenylyl cyclase
        
        cAMP
        
        Inositol lipids
        
        + Protein Kinase A
        
        Activators
        
        Inhibitors
      - JAK/STAT signaling
      - + MAPK
      - General
        
        JNK
        
        MKK/MEK
        
        MNK
        
        p38
        
        Raf kinase
      - NF-κB & IκB signaling
      - + Nitric oxide signaling
      - Antioxidants
        
        + Donors / precursors
        
        Donors
        
        Other
        
        NOS
      - + PI3K/Akt signaling
      - + Akt
        
        Activators
        
        Inhibitors
        
        mTOR
        
        PI3-kinase
      - Transcription factors
      - Wnt signaling
    - Stem Cells
  - Sodium
  - + TRP
  - - Agonists
    - Blockers

Chemical Type

Product Range

Pharmacology
- + Enzymes
- - + ATPase & GTPase
  - - Activators
    - Inhibitors
    - Substrates
  - Carbonic anhydrase
  - Carboxylase
  - Caspase
  - Cholinesterase
  - + Coenzymes
  - - Activators
    - Inhibitors
  - + Cyclase
  - - + Adenylyl cyclase
    - - Activators
      - Inhibitors
    - + Guanylyl cyclase
    - - Inhibitors
      - Other
    - Other
  - + Cyclooxygenase
  - - Activators
    - Inhibitors
    - Substrates
  - + Cytochrome P450
  - - Inhibitors
    - Other
  - + Deacetylase
  - - + Histone Deacetylase (HDAC)
    - - General
      - HDAC1
      - HDAC2
      - HDAC6
      - Sirtuins (SIRT)
    - Other
  - Deaminase
  - Decarboxylase
  - + Dehydrogenase
  - - Activators
    - Inhibitors
  - Demethylase
  - Enkephalinase
  - Esterases
  - Hydrolase
  - Hydroxylase
  - + Isomerase
  - - General
    - Topoisomerase
  - + Kinase
  - - Adenosine kinase
    - + Akt
    - - Activators
      - Inhibitors
    - ALK
    - + AMP-kinase
    - - Activators
      - Inhibitors
      - Substrates
    - ATM
    - Aurora
    - CAM Kinase
    - Casein kinase
    - Chk
    - Cyclin-dependent kinase
    - DNA-dependent Protein Kinase
    - DYRK
    - FAK
    - General
    - Glycogen synthase kinase
    - Hexokinase
    - IKK
    - JAK
    - + MAPK
    - - ERK
      - General
      - + JNK
      - Activators
        
        Inhibitors
      - MKK/MEK
      - MNK
      - p38
      - Raf kinase
    - mTOR
    - Myosin light chain kinase
    - PAK
    - PDPK1
    - + PI3-kinase
    - - Activators
      - Inhibitors
    - PIKfyve
    - PLK
    - + Protein Kinase A
    - - Activators
      - Inhibitors
    - + Protein Kinase C
    - - Activators
      - Inhibitors
    - + Protein Kinase G
    - - Activators
      - Inhibitors
    - Rho kinase
    - RSK
    - Sphingosine kinase
    - Src
    - + Tyrosine Kinase
    - - General
      - + Protein Tyrosine Kinase
      - Abl
        
        General
        
        Inhibitors
        
        Pyk
        
        Syk
      - + Receptor Tyrosine Kinase
      - c-Met
        
        CSFR1/Fms
        
        EGFR
        
        FGFR
        
        FLT3
        
        HER2/ErbB2
        
        Insulin
        
        Kit
        
        PDGFR
        
        TIE2
        
        Trk
        
        VEGFR
  - Ligase
  - + Oxidases
  - - General
    - + MAO
    - - Activators
      - Inhibitors
    - Myeloperoxidase
    - NADPH oxidase
    - Peroxidase
    - Tyrosinase
  - Oxygenase
  - + Phosphatase
  - - Alkaline phosphatase
    - Calcineurin/PP2B
    - cdc25
    - Non-selective
    - PP1 & PP2A
    - PP2B
    - Protein tyrosine phosphatase
  - Phosphodiesterase
  - + Phospholipase & Lipase
  - - Activators
    - Inhibitors
  - + Polymerase & Transcriptase
  - - DNA polymerase
    - PARP
    - RNA polymerase
    - Transcriptase
  - + Protease
  - - Aminopeptidase
    - Angiotensin-converting enzyme
    - + Calpain
    - - Activators
      - Inhibitors
    - Cathepsin
    - DUB
    - Elastase
    - General
    - Matrix metalloprotease
    - + Proteasome
    - Thrombin
    - Urokinase
  - + Reductase
  - - Aldo-keto
    - General
    - HMG-CoA reductase
  - Secretase
  - Synthetase & synthase
  - Telomerase
  - Transaminase
  - + Transferase
  - - DNA Methyltransferase (DNMT)
    - General
    - Histone Acetyltransferase (HAT)
    - + Histone Methyltransferase (HMT)
- + Ion Channels
- - + Calcium
  - - Activators
    - Blockers
  - + Chloride
  - - Activators
    - Blockers
  - Cyclic nucleotide-gated
  - Ionophores, Indicators & Chelators
  - Other
  - + Potassium
  - - Activators
    - Blockers
  - + Sodium
  - - Activators
    - Blockers
  - + TRP
  - - Agonists
    - Blockers
    - TRP
- + Receptors & Transporters
- - + Adenosine
  - - + A₁
    - - Agonists
      - Antagonists
    - + A₂
    - - Agonists
      - Antagonists
    - A₃
    - + Non-selective
    - - Agonists
      - Antagonists
    - Other
  - + Adrenoceptors
  - - + α
    - - + α₁
      - Agonists
        
        Antagonists
      - + α₂
      - Agonists
        
        Antagonists
      - + Non-selective
      - Agonists
        
        Antagonists
    - + β
    - - + β₁
      - Agonists
        
        Antagonist
      - + β₂
      - Agonists
        
        antagonist
      - + β₃
      - Agonists
        
        Antagonist
      - + Non-selective
      - Agonist
        
        Agonists
        
        Antagonist
    - + Non-selective
    - - Agonists
      - Antagonists
    - Transporters
  - + Cannabinoid
  - - + CB₁
    - - Agonists
      - Antagonists / inverse agonists
    - + CB₂
    - - Agonists
      - Antagonists / inverse agonists
    - GPR18
    - GPR55
    - Non-selective
    - Other
    - Transporters
  - Catalytic Receptors
  - + Chemokine
  - - Agonists
    - Antagonists
    - Other
  - + Dopamine
  - - + D₁
    - - Agonists
      - Antagonists
    - + D₂
    - - Agonists
      - Antagonists
    - + D₃
    - - Agonists
      - Antagonists
    - + D₄
    - - Agonists
      - Antagonists
    - + D₅
    - - Agonists
      - Antagonists
    - + Non-selective
    - - Agonists
      - Antagonists
    - Other
    - Transporters
  - + Enzyme-Linked Receptors
  - - Receptor Serine/Threonine Kinases (RSTKs)
    - + Cytokine receptors
    - - Cytokines
      - Other
    - Integrin
    - + Receptor tyrosine kinases
    - - c-Met
      - CSFR1/Fms
      - EGFR
      - FGFR
      - FLT3
      - HER2/ErbB2
      - Insulin
      - Kit
      - PDGFR
      - TIE2
      - Trk
      - VEGFR
  - Free Fatty Acid Receptors
  - G protein-coupled estrogen
  - + GABA
  - - + GABA_A
    - + GABA_B
    - + Non-selective
    - - Agonists
      - Antagonists
    - Other
    - Transporters
  - + Glutamate
  - - + AMPA & Kainate
    - + Broad spectrum / non-selective
    - + mGlu
    - - General
      - + Group I
      - Agonists
        
        Allosteric modulators
        
        Antagonists
      - + Group I & II
      - Agonists
        
        Allosteric modulators
        
        Antagonists
        
        Antibodies
      - + Group II
      - Agonists
        
        Allosteric modulators
        
        Antagonists
        
        Antibodies
      - + Group III
      - Agonists
        
        Allosteric modulators
        
        Antagonists
    - + NMDA
    - - AP-2 binding site
      - + Glutamate Site
      - Agonists
        
        Antagonists
      - + Glycine Site
      - Agonists
        
        Antagonists
      - Ion Channel Site
      - + Polyamine Site
      - Agonists
        
        Antagonists
        
        Other
    - + Transporters
    - - Inhibitors
      - Modulators
  - + Glycine
  - - Agonists
    - Antagonists
    - Transporters
  - + Histamine
  - - + H₁
    - - Agonists
      - Antagonists
    - + H₂
    - - Agonists
      - Antagonists
    - + H₃
    - + H₄
    - - Agonists
      - Antagonists
    - Histaminergic-Related Compounds
    - Non-selective
  - + Imidazoline
  - - Agonists
    - Antagonists
  - Inositol triphosphate receptor
  - Leukotriene & Related
  - Lysophospholipid receptor
  - + Melatonin
  - - MT₁
    - + MT₂
    - - Agonists
      - Antagonists
    - MT₃
  - + Muscarinic
  - - + M₁
    - + M₂
    - - Agonists
      - Antagonists
    - + M₃
    - - Agonists
      - Antagonists
    - M₄
    - M₅
    - + Non-selective
    - - Agonists
      - Antagonists
  - + Nicotinic
  - - α3
    - α4β2
    - + α7
    - - Agonists
      - Antagonists
    - + General
    - - Agonists
      - Antagonists
  - + Nuclear Receptors
  - - Androgen receptors
    - Aryl hydrocarbon receptors
    - Constitutive androstane receptor
    - + Estrogen
    - - Agonists
      - Antagonists
    - Glucocorticoid
    - LXR-like receptors
    - Mineralocorticoid
    - PPAR
    - Pregnane receptors
    - Progesterone
    - Retinoic acid receptors
    - Retinoid X receptors
    - VDR-like receptors
  - + Opioids
  - - + δ
    - - Agonists
      - Antagonists
    - + κ
    - - Agonists
      - Antagonists
    - + General
    - - Agonists
      - Antagonists
    - ORL₁
    - + µ
    - - Agonists
      - Antagonists
  - Orphan 7-TM Receptors
  - + Peptide Receptors
  - - + Angiotensin
    - - AT₁
      - AT₂
    - Apelin
    - AXOR
    - Bombesin
    - Bradykinin
    - Calcitonin and Related Receptors
    - CCK
    - + CRF
    - - Agonists
      - Antagonists
    - + Endothelin
    - - Agonists
      - Antagonists
    - + Galanin
    - - Agonists
      - Antagonists
    - + Ghrelin
    - - Agonists
      - Antagonists
    - + Glucagon and Related Receptors
    - - Agonists
      - Antagonists
    - LHRH
    - Melanocortin
    - Melanocyte Stimulating Hormone
    - Motilin
    - Neuromedin
    - Neuropeptide FF/AF Receptors
    - Neuropeptide S
    - Neuropeptide Y
    - Neurotensin
    - + Orexin
    - - Agonists
      - Antagonists
    - + Other
    - - Agonists
      - Antagonists
    - Oxytocin
    - + PAR
    - - Agonists
      - Antagonists
    - Sensory Neuron Specific Receptor
    - Somatostatin
    - Substance P
    - + Tachykinins
    - - Agonists
      - Antagonists
    - Urotensin
    - Vasopressin
    - VIP
  - Platelet-Activating Factor (PAF)
  - Prostanoid
  - + Purinergics
  - - + P1
    - - Agonists
      - Antagonists
    - + P2
    - - Non-selective
      - + P2X
      - Agonists
        
        Antagonists
      - + P2Y
      - Agonists
        
        Antagonists
  - + Serotonin
  - - + 5-HT₁
    - - + 5-HT_1A
      - Agonists
        
        Antagonists
      - + 5-HT_1B
      - Agonists
        
        Antagonists
      - 5-HT_1C
      - + 5-HT_1D
      - Agonists
        
        Antagonists
      - 5-ht_1e
      - 5-HT_1F
    - + 5-HT₂
    - - + 5-HT_2A
      - Agonists
        
        Antagonists
      - + 5-HT_2B
      - Agonists
        
        Antagonists
      - + 5-HT_2C
      - Agonists
        
        Antagonists
      - + Non-selective
      - Agonists
        
        Antagonists
    - + 5-HT₃
    - - Agonists
      - Antagonists
    - + 5-HT₄
    - - Agonists
      - Antagonists
    - 5-HT₅
    - + 5-HT₆
    - - Agonists
      - Antagonists
    - + 5-HT₇
    - - Agonists
      - Antagonists
    - + Non-selective
    - - Agonists
      - Antagonists
    - Transporters
  - Sigma
  - Smoothened
  - Sphingosine 1-Phosphate Receptors
  - TGR5
  - Toll-like Receptors
  - + Transporters
  - - ABC transporter
    - Adrenergic
    - Cannabinoid
    - Dopamine
    - GABA
    - Glutamate
    - Glutamine
    - Glycine
    - + Ion pumps / transporter
    - Serotonin
- + Signaling
- - Amyloidogenesis
  - + Angiogenesis
  - - Antiangiogenics
    - VEGFR
  - + Apoptosis & cell cycle
  - - BCL
    - Caspase
    - Chk
    - Cyclin-dependent kinase
    - + Growth factors
    - - ALK
      - EGFR
      - FGFR
      - General
      - Kit
      - PDGFR
      - Trk
      - VEGFR
    - Other
    - + p53
    - - Activators
      - Inhibitors
    - PARP
  - + Ca²⁺ signaling
  - - Ca_v channels
    - Ca²⁺ binding protein
    - Ca²⁺-ATPase
    - CAM Kinase
    - Chelators
    - General
    - Ionophores, Indicators & Chelators
    - IP₃ & ryanodine receptors
    - Na⁺/Ca²⁺ exchange
  - + Cytoskeleton & motor proteins
  - - Actin
    - Inhibitors
    - Kinesin
    - Myosin
    - Other
    - Tubulin
  - + DNA, RNA & protein synthesis
  - - DNA & RNA synthesis
    - General
    - Polymerase and transcriptase
    - Protein synthesis
    - Topoisomerase
    - Transcription factors
  - + Endocytosis & exocytosis
  - - Clathrin
    - Dynamin
    - Other
  - + Epigenetics
  - - DNA Methyltransferases (DNMTs)
    - Histone Acetyltransferases (HATs)
    - Histone Deacetylases (HDAC)
    - Histone Methyltransferase (HMT)
    - Other
  - + Extracellular matrix & cell adhesion
  - - Cell adhesion
    - Focal adhesion kinase
    - Matrix metalloprotease
    - Rho kinase
  - Heat Shock Proteins
  - + Immunomodulators
  - - Antibacterial
    - Antifungal
    - Antiparasitic
    - Antiviral
    - Immunomodulators & Immunosuppressants
    - Other
  - + Lipid signaling
  - - Cyclooxygenase
    - Diacylgycerol kinase
    - Fatty acid amide hydrolase
    - Fatty acid synthase
    - General
    - HMG-CoA reductase
    - Inhibitors
    - Metabolism
    - Oxygenase
    - + Phospholipase & Lipase
    - - Activators
      - Inhibitors
    - PI3-kinase
    - Prostaglandins
  - + Signal transduction
  - - Cytokines, NF-κB & IκB signaling
    - G-Protein related
    - + Hedgehog signaling
    - + Inositol & cAMP signaling
    - + JAK/STAT
    - - JAK
      - + STAT
      - Activators
        
        Inhibitors
    - + MAPK
    - - + ERK
      - Activators
        
        Inhibitors
      - General
      - + JNK
      - Activators
        
        Inhibitors
      - MKK/MEK
      - MNK
      - p38
      - Raf kinase
    - + Nitric oxide & oxidative stress
    - - Antioxidants
      - + Donors / precursors
      - Donors
        
        Other
      - NOS
      - Other
      - ROS
    - Notch signaling
    - + PI3K/Akt signaling
    - - + Akt
      - Activators
        
        Inhibitors
      - Glycogen synthase kinase
      - Inhibitors
      - mTOR
      - p21
      - + PI3-kinase
      - Activators
        
        Inhibitors
      - PP1 & PP2A
    - + Wnt signaling
    - - Activators
      - Inhibitors
  - + Stem Cells
  - - Growth factors
    - Hedgehog signaling
    - JAK/STAT
    - Other
    - Wnt signaling

We have 2 products in: Biochemicals >> Research Area >> Alzheimer's Disease >> Nitric oxide signaling >> Donors / precursors >> Other

Other

Code

Name

Details

Image Abreview Publication

Precursor to nitric oxide synthesis

Purity: > 99%

3-Morpholinosydnonimine hydrochloride (SIN-1 hydrochloride)

Vasodilator. Active metabolite of molsidomine.

Purity: > 99%

Get resources and offers direct to your inbox Sign up