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There has long been a connection between proteases and cancer biology, since these enzymes can endow tumour cells with the ability to invade and metastasize, or spread through the body. However, we now know that proteases are involved in a host of subtle regulatory mechanisms that determine the extracellular environment, and how cells respond to their environments, and in so doing they can control cancer cell growth and death, the formation of new blood vessels (angiogenesis) that supply the growing tumour with nutrients, and also the ability of the immune system to detect cancers. It is this set of protease genes, together with their natural inhibitors, and the proteins with which they interact, that is called the DEGRADOME. We can only now appreciate that any attempt to understand the relevance of proteases in cancer must consider the extraordinary diversity and versatility of these enzymes in different contexts.
This workshop will combine the findings of the EU Framework 6 Programme on the ‘Cancer Degradome’ with those of other colleagues in the field. The focus will be on extracellular proteinases and their status as markers and therapeutic targets in cancer. The use of novel techniques to study aspects of their in vitro and in vivo functions will be a particular focus.
8 - 9 October 2008
Day 2 (9 October): 09:00 - 16:15
Call for abstracts
Abstracts (oral and poster) which fit the themes outlined above are now invited
Deadline for oral abstracts: Monday 14 July 2008
Deadline for poster abstracts: Monday 15 September 2008
Early bird fee: Standard rate:
£175 full £225 full
£125 students £175 students
All prices are inclusive of VAT and include access to sessions; lunch and refreshments on 8 and 9 October; attendance at the welcome reception; book of abstracts and other conference materials.
Students are categorized as those in full time education at the time of registering. Proof of student status may be requested.
Early bird deadline:Monday 14 July 2008 (standard rates apply after this time)
EACR meeting bursary!
Student Group Discounts
Register 4 and get 1 free!
Discounts are available for student groups attending from the same institution: register four and the fifth can attend for free. Telephone +44 (0)1223 696000 for further information.
Group Discounts - Terms & Conditions
Ellis Salsby Ltd is the appointed agent to handle the accommodation for this event. They have negotiated preferential rates at local hotels. Delegates requiring accommodation can see the Ellis Salsby website to view and book accommodation available.
Alternatively Visit London is the official website for visitors to the City with comprehensive guides to accommodation, transport and attractions.
Abcam would like to acknowledge the support of the British Society for Matrix Biology and the European Association for Cancer Research for this meeting.
Terms and conditions
Delegates are advised to ensure they have adequate travel insurance to cover their attendance at the conference in case of incident, or cancellation due to circumstances beyond Abcam's control.
If you have any questions please email Abcam Events Team or call +44 (0) 1223 696000
We look forward to welcoming you to London