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Cardiac Development and Regeneration symposium

October 10-11, 2008, Boston, MA

Register and submit your abstract now!

Wnt/beta-catenin signaling in cardiac development

    Wnt/beta-catenin signaling

In honor of this meeting, we have just released the latest in our series of Cardiovascular-related pathway cards.

Wnt signaling controls crucial aspects of cardiovascular biology including cardiac morphogenesis, and the self-renewal and differentiation of cardiac progenitor cells. As shown on our new pathway card, the ability of Wnt signaling to regulate such different aspects of cardiovascular development rests on the diverse downstream targets affected by this pathway.

PDF Download the pathway

                Boston Cardio Meeting

Venue:

Doubletree Guest Suites Boston
400 Soldiers Field Road (map)
Boston, Massachusetts

Date:

October 10 - 1, 2008

Time:

October 10th: 9:00am to 5:00pm
October 11th: 9:00am to 5:00pm
Please join us after the meeting on October 10th for a reception and poster session.

Organizers:

Dr. Jonathan Epstein, M.D. and Dr. Edward Morrisey, Ph.D. in association with Abcam, Inc.

Contents:

Topics:

  • Early cardiovascular development
  • Epigenetics
  • Reprogramming and cardiac progenitors
  • Genomics
  • Molecular pathways and congenital heart disease
  • Cardiac stem cells and regeneration

Invited speakers:

  • Keynote: Cliff Tabin, Chairman, Department of Genetics, Harvard Medical School
    Morphogenesis of the heart and other organs
  • Margaret Buckingham, Department of Developmental Biology, Pasteur Institute, France
    Cardiac progenitor cells of the second heart field in the mouse embryo
  • Deepak Srivastava, Gladstone Institute, UCSF
    microRNA regulation of cardiac stem cells and regeneration
  • Benoit Bruneau, Gladstone Institute, UCSF
    Chromatin remodeling in heart development
  • William Pu, Children's Hospital of Boston, Harvard Medical School
    Epicardial-derived Wt1+ progenitors contribute to the cardiomyocyte lineage in the embryonic and adult heart
  • Debbie Yelon, Skirball Institute, New York University School of Medicine
    Signaling pathways that shape the heart field in zebrafish
  • Stephen Duncan, Medical College of Wisconsin
    Control of cardiac development by Gata4 and Gata6
  • Michael Parmacek, Division of Cardiovascular Medicine, University of Pennsylvania
    Myocardin related transcription factors: Critical co-activators regulating heart and outflow tract development
  • Nathan Lawson, University of Massachusetts Medical School
    Transcriptional control of endothelial cell identity
  • Sean Wu, Cardiovascular Research Center, Massachusetts General Hospital
    iPS, ES, or endogenous cells in cardiac regeneration
  • Kenneth Chien, Massachusetts General Hospital Cardiovascular Research Center
    Towards human models of human heart disease: The islet-1 heart progenitor story
  • John Mably Children’s Hospital, Boston
    Genetic regulation of cardiac development in zebrafish
  • Edward Morrisey, University of Pennsylvania
    Wnt signaling and regulation of cardiac and lung development
  • Jonathan Epstein, University of Pennsylvania
    Notch signaling in cardiovascular development

Oral presentations selected from submitted abstracts:

  • José Luis de la Pompa, Centro Nacional de Biotecnología
    Notch signalling in cardiac valve development
  • Carolyn Gaydos, Tufts University
    Notch signaling regulates cell fate decisions during cardiac field formation in Xenopus laevis
  • Lisa Chang, Baker IDI Heart and Diabetes Research Institute
    Contextual dependent reprogramming of the SWI/SNF complex allows it to differentially serve as a transcriptional co-regulator at promoters of the hypertrophied heart
  • Ivan Moskowitz, University of Chicago
    Hedgehog-dependent atrial septum progenitors are required for cardiac septation
  • Patricia Labosky, Vanderbilt University
    Progenitor pool size is not a critical determinant of cardiac neural crest function
  • Rolf Bodmer, Burnham Institute for Medical Research
    Discovering cardiac disease genes in Drosophila
  • Neil Chi, University of California, San Francisco
    Foxn4 directly regulates tbx2b expression for the evolutionary division of the vertebrate heart
  • Steven Kattman, McEwen Centre for Regenerative Medicine
    Establishment of cardiac mesoderm is regulated by ActivinA and BMP4 during mouse and human ES and iPS cell differentiation
  • Ian Scott, The Hospital for Sick Children
    Regulation of cardiac progenitor development by Agtrl1 signaling in zebrafish
  • Benjamin Herdrich, Children’s Hospital of Philadelphia
    Regenerative healing following fetal myocardial infarction
  • Laura Zelarayan, Max Delbrueck Center for Molecular Medicine
    Inhibition of ß-catenin attenuates left ventricular remodeling after myocardial infarction through enhanced cardiac stem cell differentiation

Program:

Full schedule also available for pdf download.

Friday, October 10, 2008

8:00am

Registration

9:00am

Welcome, meeting chairs 

9:10am

Keynote: Morphogenesis of the heart and other organs
Cliff Tabin, Chairman, Department of Genetics, Harvard Medical School

9:50am

Control of cardiac development by Gata4 and Gata6
Stephen Duncan, Medical College of Wisconsin

10:25am

Chromatin remodeling in heart development 
Benoit Bruneau, Gladstone Institute, UCSF 

11:10am

Coffee break

11:40am

Towards human models of human heart disease: The islet-1 heart progenitor story
Kenneth Chien, Massachusetts General Hospital Cardiovascular Research Center

12:15pm

Notch signaling regulates cell fate decisions during cardiac field formation in Xenopus laevis
Carolyn Gaydos, Tufts University

12:35pm

Notch signalling in cardiac valve development
José Luis de la Pompa, Centro Nacional de Biotecnología

12:55pm

Lunch

1:55pm

Myocardin related transcription factors: Critical co-activators regulating heart and outflow tract development
Michael Parmacek, Division of Cardiovascular Medicine, University of Pennsylvania

2:30pm    

Epicardial-derived Wt1+ progenitors contribute to the cardiomyocyte lineage in the embryonic and adult heart
William Pu, Children’s Hospital of Boston, Harvard Medical School

3:05pm

Coffee break

3:35pm

microRNA regulation of cardiac stem cells and regeneration
Deepak Srivastava, Gladstone Institute, UCSF

4:10pm

Contextual dependent reprogramming of the SWI/SNF complex allows it to differentially serve as a transcriptional co-regulator at promoters of the hypertrophied heart
Lisa Chang, Baker IDI Heart and Diabetes Research Institute

4:30pm

Transcriptional control of endothelial cell identity
Nathan Lawson, University of Massachusetts Medical School

5:05pm   

Reception and poster session

Saturday, October 11, 2008

9:00am

Cardiac progenitor cells of the second heart field in the mouse embryo
Margaret Buckingham, Department of Developmental Biology, Pasteur Institute, France

9:35am

Hedgehog-dependent atrial septum progenitors are required for cardiac septation
Ivan Moskowitz, University of Chicago

9:55am

Progenitor pool size is not a critical determinant of cardiac neural crest function
Patricia Labosky, Vanderbilt University

10:15am

Coffee break

10:45am

Signaling pathways that shape the heart field in zebrafish
Debbie Yelon, Skirball Institute, New York University School of Medicine

11:20am

iPS, ES or endogenous cells in cardiac regeneration
Sean Wu, Cardiovascular Research Center, Massachusetts General Hospital

11:55am

Discovering cardiac disease genes in Drosophila
Rolf Bodmer, Burnham Institute for Medical Research

12:15am

Foxn4 directly regulates tbx2b expression for the evolutionary division of the vertebrate heart
Neil Chi, University of California, San Francisco

12:35pm

Lunch

1:30pm

Notch signaling in cardiovascular development
Jonathan Epstein
, University of Pennsylvania

2:05pm  

Genetic regulation of cardiac development in zebrafish
John Mably, Children’s Hospital, Boston

2:40pm    

Establishment of cardiac mesoderm is regulated by ActivinA and BMP4 during mouse and human ES and iPS cell differentiation 
Steven Kattman, McEwen Centre for Regenerative Medicine 

3:00pm

Coffee break

3:25pm

Wnt signaling and regulation of cardiac and lung development
Edward Morrisey, University of Pennsylvania

4:00pm

Regulation of cardiac progenitor development by Agtrl1 signaling in zebrafish
Ian Scott, The Hospital for Sick Children

4:20pm

Regenerative healing following fetal myocardial infarction
Benjamin Herdrich, University of Pennsylvania School of Medicine

4:40pm

Inhibition of ß-catenin attenuates left ventricular remodeling after myocardial infarction through enhanced cardiac stem cell differentiation
Laura Zelarayan, Max Delbrueck Center for Molecular Medicine

Registration:

Early Bird
Register by August 10, 2008

Standard
Register after August 10, 2008

Regular

$190.00

$250.00

Student

$125.00

$175.00

The registration fee includes lunch and coffee on both days and a wine reception on October 10th. Register and submit your abstract online.

Students are categorized as those in full-time education at the time of registering. Proof of student status may be requested.

If you are paying via American Express, please contact Katie via email or at 617-577-4263 since we cannot take the cards online at the moment.

Posters:

A full list of registered posters including title and presentor is available for download. PDF

Posters will be judged. The winner will receive up to $150 off their registration for a future Abcam conference or an antibody from the Abcam catalog.

Posters must not be larger than four feet tall by four feet wide.

Flier: 

Download the flier for the meeting.PDF (Warning - large file)

Feel free to print it out and distribute it at your organization.

Accommodation:

A block of rooms at the Doubletree Guest Suites Boston have been set aside. Please contact the hotel at 1-800-222-8733 and mention "Abcam" to reserve your room at a special rate. Rooms must be reserved by Monday, September 8, 2008 to take advantage of this special price. You can also reserve your room online.

Directions to venue:

The hotel is located just off I-90 (Mass Turnpike).

  • East Bound: take Exit 18-Brighton/Cambridge.
  • West Bound: take Exit 20-Brighton/Cambridge.

From Logan International Airport, exit via the Ted Williams Tunnel, follow sign to I-90W and take Exit 20-Brighton/Cambridge, after paying toll, bear right towards Cambridge. At second light turn right, hotel driveway is on your right.

A taxi from Logan International Airport is approximately $30.00.

Here are detailed instructions on how to get to the DoubleTree Hotel Boston. For maps please see the venue's website.

Public transportation:

The Doubletree is close to many MBTA bus stops. Visit the MBTA web site for more information.

Sponsorship:

If you are interested in sponsoring or exhibiting at this meeting, please contact us for more information.

For more information:

Katie Sedat, Abcam Events Team
Phone: 617-577-4263

Register and submit your abstract now!

Cancellation Terms and Conditions
Delegates are advised to ensure they have adequate travel insurance to cover their attendance at the conference in case of incident, or cancellation due to circumstances beyond Abcam's control.

  • All fees paid to Abcam, including registration are non-refundable.
  • Substitute delegates can be made at any time by contacting events@abcam.com.
Check out our other upcoming Cardiovascular meeting:

Molecular Regulation of Cardiac Disease symposium
May 14 - 15, 2009 - London, UK
View meeting details and register.

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