Past event: Apoptosis and Cancer conference: The Bcl-2 family of proteins

June 25-26, 2009 - Dartmouth College, NH

This event has now passed - please visit our Conference calendar for future Abcam events

For a report on this succesful conference, please visit the Abcam blog.

A list of poster presentations is now available for PDF download.

dartmouth clock tower height 298


Dartmouth College
Hanover, New Hampshire USA

Click here for directions on how to travel to Dartmouth College.


June 25-26, 2009


Thursday, June 25, 2009 9am-7pm

Friday, June 26, 2009 9am-5pm


Barbara Conradt (Dartmouth Medical School), Marie Hardwick (Johns Hopkins University), and Abcam, Inc.


The Bcl-2 family of proteins (Bcl-2-like proteins, Bax/Bak, BH3-only proteins):

  • Regulation and role in apoptosis and tumorigenesis
  • Non-apoptotic functions
  • Targets for the development of cancer therapeutics



Invited speakers:

  • David Vaux (La Trobe University)
    BH3-only proteins: accomplices or accessories to murder?
  • Nika Danial (Dana-Farber Cancer Institute)
    Metabolism meets apoptosis: a role for pro-apoptotic BAD in glucose sensing
  • Gordon Shore (McGill University)
    Bcl-2 Inhibition for the Treatment of Cancer
  • Elizabeth Jonas (Yale University)
    BCL-xL in the synapse: How a mitochondrial protein regulates neuronal activity
  • Richard Youle (NINDS)
    Bcl-2 family proteins, apoptosis and mitochondrial morphogenesis
  • Andreas Strasser (Walter & Eliza Hall Institute of Medical Research)
    The role of the Bcl-2 protein family in tumorigenesis and cancer therapy
  • Gerald Cohen (University of Leicester)
    BCL2 inhibitors and chronic lymphocytic leukemia
  • Marie Hardwick (Johns Hopkins University)
    Non-canonical functions of Bcl-2 family proteins - neurons to yeast
  • Saul Rosenberg (Abbott Laboratories)
    Apoptosis as a therapeutic target: Inhibiting the Bcl-2 family proteins
  • A. Thomas Look (Dana Farber Cancer Institute)
    Chk1 suppresses a Caspase-2 apoptotic response to DNA damage that bypasses p53, Bcl-2 and Caspase-3
  • David Andrews (McMaster University)
    Embedded together: The life and death consequences of interaction of the Bcl-2 family with membranes
  • Ruth Craig (Dartmouth Medical School)
    MCL1 regulation and dysregulation: How cells change their minds and how defects in this process contribute to cancer
  • Alan Eastman (Dartmouth Medical School)
    Bcl2 inhibitors as adjuvants to chemotherapy
  • Barbara Conradt (Dartmouth Medical School)
    Regulation and function of Bcl-2 family members in C. elegans

The full conference program is available as a PDF download.

Talks froms submitted abstracts:

  • Elizabeth Tanner (Boston University)
    Regulation of mitochondrial clustering by Bcl-2 family proteins during programmed cell death in the Drosophila ovary
  • Brian Polster (University of Maryland School of Medicine)
    Bioenergetics-based evaluation of Bcl-2 antagonists in cancer and normal cells
  • Varda Shoshan-Barmatz (Ben-Gurion University) 
    The anti-apoptotic protein Bcl2 regulates apoptosis via interaction with the mitochondrial protein, VDAC1 
  • Angelika Böttger (Ludwig-Maximilians-University Munich)
    Bcl-2 proteins in the early metazoan Hydra
  • Sophie Cazanave (Mayo Clinic Foundation)
    JNK1-dependent PUMA expression contributes to Lipoapoptosis
  • Lina Ghibelli (Universita’ di Roma Tor)
    Redox modulation of Bax and Bcl-2: disulfides in apoptosis and survival
  • W. Gibson Wood (University of Minnesota)
    Simvastatin induction of Bcl-2 expression and neuroprotection in mouse primary neurons and human neuroblastoma cells independent of the mevalonate/isoprenoid/cholesterol pathways
  • Jialing Lin (University of Oklahoma)
    Interfaces of Bax homo- and Bax/Bcl-2 hetero-olgimerization are distinct but overlapping
  • Jason Pellettieri (University of Utah)
    Cell death and tissue remodeling in Planarian regeneration
  • Sabrina Spencer (Massachusetts Institute of Technology) 
    Non-genetic origins of cell-to-cell variability in TRAIL-induced apoptosis
  • Chunxin Wang (National Institute of Neurological Disorders and Stroke)
    Multiple steps of Bax activation revealed by loss-of-function Bax mutants

The full conference program is available as a PDF download.

Target audience:

Basic scientists, translational investigators and clinical researchers at various stages of their career interested in the role of Bcl-2 family members in apoptosis and tumorigenesis. Lectures, poster presentations and informal discussions will allow ample possibilities for interactions among participants!


Abcam would like acknowledge the following organizations for their support of the meeting:



North American Vascular Biology Organization

John Wiley & Sons, Inc.

If you are interested in sponsoring or exhibiting at this meeting, please contact us for more information.



The full conference program is now available as a PDF download.



There are two registration types for this meeting.

Delegate and Student includes accommodations for the nights of June 24th and June 25th. This accommodation is in air-conditioned Dartmouth College dorm.

Local - Delegate and Local - Student does not include two nights accommodations.

Both registration types include lunch on the 25th and 26th and a barbecue dinner on the evening of the 25th.





Local - Delegate


Local - Student


The registration fee includes:

  • $41.00 meal credit at Dartmouth College dining services
  • Abstract book
  • Group Italian dinner Thursday night at Hopkins Center catered by the Hanover Inn
  • On-campus parking

Students are categorized as those in full-time education at the time of registering. Proof of student status may be requested.


For the Delegates and Students electing to stay in the Dartmouth College dormatories, extra nights are available for the nights of June 23, 2009 and June 26, 2009. The cost is $50.00 a night and $100.00 for both. If you want additional night accommodations, please e-mail


New! A list of poster presentations is now available for PDF download.

Don’t miss your chance to view these posters and meet with the presenters. Each attendee will recieve a program with abstracts from posters and oral presenations.

Posters will be judged. The winner will receive up to $150 off their registration for a future Abcam conference or an antibody from the Abcam catalog.

Visiting the area:

Make your trip a long weekend so you can enjoy all the great activites New Hampshire and Vermont have to offer.

For more information:

Katie Sedat, Abcam Events Team
Phone: 617-577-4263

Cancellation terms and conditions:

Delegates are advised to ensure they have adequate travel insurance to cover their attendance at the conference in case of incident, or cancellation due to circumstances beyond Abcam's control.

  • All fees paid to Abcam, including registration are non-refundable.
  • Substitute delegates can be made at any time by contacting

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