Fc chimeric Human expressed proteins | highly purified

Some human expressed proteins are produced as extracellular domain regions fused to the Fc region of human IgG1.

Fc fusion proteins can play a role in dimerization, in vivo half-life, receptor activation and affinity for the cognate ligand. They have an advantage over soluble receptors as many receptors are only functional in a dimeric form; the dimeric receptor Fc can then mimic the activated form and enhance its affinity for the cognate ligand.

Fc chimeric proteins contain human-specific glycosylation and are suited for studies involving human proteins and cells. They can be used to neutralize the bioactivity of their cognate ligands in vitro and in vivo. They can also be used in studies to quantify receptor-ligand affinity by surface plasmon resonance.

For further information or help contact our Scientific Support team.

Contents

  1. Full length proteins
  2. Protein fragments

1. Full length proteins


Product

Applications

Protein code

CD40 protein (Fc Chimera Active)

FuncS, SDS-PAGE

ab83917

GM-CSF Receptor alpha protein (Fc Chimera Active)

SDS-PAGE

ab83993

IFNAR2 protein (Fc Chimera Active)

FuncS, SDS-PAGE

ab83680

IL3RB protein (Fc Chimera)

SDS-PAGE

ab83919

TrkC protein (Fc Chimera)

FuncS, SDS-PAGE

ab85599

2. Protein fragments

Product

Applications

Protein code

Activin Receptor Type IA protein (Fc Chimera)

SDS-PAGE

ab83922

BAFF Receptor protein (Fc Chimera Active)

SDS-PAGE

ab83931

CD134 / OX40 protein (Fc Chimera)

SDS-PAGE

ab83676

CD299 protein (Fc Chimera)

SDS-PAGE

ab83920

CD62L protein (Fc Chimera)

SDS-PAGE

ab83824

CD62P protein (Fc Chimera Active)

FuncS, SDS-PAGE

ab83583

c-Kit protein (Fc Chimera Active)

FuncS, SDS-PAGE

ab88349

Cripto1 protein (Fc Chimera Active)

SDS-PAGE

ab84062

DR5 protein (Fc Chimera Active)

FuncS, SDS-PAGE

ab83547

EGFR protein (Fc Chimera Active)

FuncS, SDS-PAGE

ab84002

EPO Receptor protein (Fc Chimera Active)

FuncS, SDS-PAGE

ab84001

FGFR1 alpha protein (Fc Chimera)

SDS-PAGE

ab84000

FGFR4 protein (Fc Chimera)

SDS-PAGE

ab83999

Flt3 / CD135 protein (Fc Chimera Active)

FuncS, SDS-PAGE

ab83998

GCSF Receptor protein (Fc Chimera Active)

FuncS, SDS-PAGE

ab83994

Growth hormone receptor protein (Fc Chimera)

SDS-PAGE

ab83991

IFN gamma Receptor beta protein (Fc Chimera)

SDS-PAGE

ab83988

IFNGR1 protein (Fc Chimera Active)

SDS-PAGE

ab83990

IL1 Receptor I protein (Fc Chimera)

SDS-PAGE

ab83575

IL2 Receptor alpha protein (Fc Chimera Active)

SDS-PAGE

ab84071

IL2 Receptor beta protein (Fc Chimera Active)

SDS-PAGE

ab84068

IL2 Receptor gamma protein (Fc Chimera)

SDS-PAGE

ab84065

IL3RA protein (Fc Chimera)

FuncS, SDS-PAGE

ab88358

IL4RA protein (Fc Chimera)

SDS-PAGE

ab83756

IL5RA protein (Fc Chimera)

SDS-PAGE

ab83828

IL5RA protein (Fc Chimera)

SDS-PAGE

ab85983

IL7RA alpha protein (Fc Chimera)

SDS-PAGE

ab83827

IL10RA protein (Fc Chimera)

SDS-PAGE

ab83687

MCSF protein (Fc Chimera Active)

FuncS, SDS-PAGE

ab83682

p75 NGF Receptor protein (Fc Chimera Active)

FuncS, SDS-PAGE

ab83678

p75 NGF Receptor protein (Fc Chimera)

SDS-PAGE

ab83679

TGF beta Receptor II protein (Fc Chimera)

SDS-PAGE

ab83578

TNF Receptor I protein (Fc Chimera Active)

FuncS, SDS-PAGE

ab83577

TNF Receptor II protein (Fc Chimera Active)

FuncS, SDS-PAGE

ab83541

TrkA protein (Fc Chimera)

SDS-PAGE

ab83562

TrkB protein (Fc Chimera Active)

FuncS, SDS-PAGE

ab83565

View our active and inactive human expressed proteins

View the full range of proteins and peptides