Fc fusion proteins can play a role in dimerization, in vivo half-life, receptor activation and affinity for the cognate ligand. They have an advantage over soluble receptors as many receptors are only functional in a dimeric form; the dimeric receptor Fc can then mimic the activated form and enhance its affinity for the cognate ligand.
Fc chimeric proteins contain human-specific glycosylation and are suited for studies involving human proteins and cells. They can be used to neutralize the bioactivity of their cognate ligands in vitro and in vivo. They can also be used in studies to quantify receptor-ligand affinity by surface plasmon resonance.
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Contents
- Full length proteins
- Protein fragments
1. Full length proteins
2. Protein fragments
Product | Applications | Protein code |
|---|
Activin Receptor Type IA protein (Fc Chimera) | SDS-PAGE | ab83922 |
BAFF Receptor protein (Fc Chimera Active) | SDS-PAGE | ab83931 |
CD134 / OX40 protein (Fc Chimera) | SDS-PAGE | ab83676 |
CD299 protein (Fc Chimera) | SDS-PAGE | ab83920 |
CD62L protein (Fc Chimera) | SDS-PAGE | ab83824 |
CD62P protein (Fc Chimera Active) | FuncS, SDS-PAGE | ab83583 |
c-Kit protein (Fc Chimera Active) | FuncS, SDS-PAGE | ab88349 |
Cripto1 protein (Fc Chimera Active) | SDS-PAGE | ab84062 |
DR5 protein (Fc Chimera Active) | FuncS, SDS-PAGE | ab83547 |
EGFR protein (Fc Chimera Active) | FuncS, SDS-PAGE | ab84002 |
EPO Receptor protein (Fc Chimera Active) | FuncS, SDS-PAGE | ab84001 |
FGFR1 alpha protein (Fc Chimera) | SDS-PAGE | ab84000 |
FGFR4 protein (Fc Chimera) | SDS-PAGE | ab83999 |
Flt3 / CD135 protein (Fc Chimera Active) | FuncS, SDS-PAGE | ab83998 |
GCSF Receptor protein (Fc Chimera Active) | FuncS, SDS-PAGE | ab83994 |
Growth hormone receptor protein (Fc Chimera) | SDS-PAGE | ab83991 |
IFN gamma Receptor beta protein (Fc Chimera) | SDS-PAGE | ab83988 |
IFNGR1 protein (Fc Chimera Active) | SDS-PAGE | ab83990 |
IL1 Receptor I protein (Fc Chimera) | SDS-PAGE | ab83575 |
IL2 Receptor alpha protein (Fc Chimera Active) | SDS-PAGE | ab84071 |
IL2 Receptor beta protein (Fc Chimera Active) | SDS-PAGE | ab84068 |
IL2 Receptor gamma protein (Fc Chimera) | SDS-PAGE | ab84065 |
IL3RA protein (Fc Chimera) | FuncS, SDS-PAGE | ab88358 |
IL4RA protein (Fc Chimera) | SDS-PAGE | ab83756 |
IL5RA protein (Fc Chimera) | SDS-PAGE | ab83828 |
IL5RA protein (Fc Chimera) | SDS-PAGE | ab85983 |
IL7RA alpha protein (Fc Chimera) | SDS-PAGE | ab83827 |
IL10RA protein (Fc Chimera) | SDS-PAGE | ab83687 |
MCSF protein (Fc Chimera Active) | FuncS, SDS-PAGE | ab83682 |
p75 NGF Receptor protein (Fc Chimera Active) | FuncS, SDS-PAGE | ab83678 |
p75 NGF Receptor protein (Fc Chimera) | SDS-PAGE | ab83679 |
TGF beta Receptor II protein (Fc Chimera) | SDS-PAGE | ab83578 |
TNF Receptor I protein (Fc Chimera Active) | FuncS, SDS-PAGE | ab83577 |
TNF Receptor II protein (Fc Chimera Active) | FuncS, SDS-PAGE | ab83541 |
TrkA protein (Fc Chimera) | SDS-PAGE | ab83562 |
TrkB protein (Fc Chimera Active) | FuncS, SDS-PAGE | ab83565 |
View our active and inactive human expressed proteins
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