JAK/STAT signaling pathway card

JAK/STAT signaling pathway card

The Janus kinase (JAK) / signal transducers and activators of transcription (STAT) pathway transmits signals from a wide range of cytokines and growth factors through the cell membrane and into the cell nucleus, where it leads to the transcription of the respecitve target genes. The pathway contributes significantly to the integrity of organisms. Its activation plays an important role in various cellular processes such as growth, immune response, proliferation and hematopoiesis.

Our new pathway card shows all key steps in this important signaling pathway.  

Download the JAK/STAT signaling pathway card (2.3MB).

 

View all pathway cards and posters.

 

We have a wide range of products for JAK/STAT pathway research. A selection can be found here:

 

Antibodies:

Antibody

Clonality

Application

Host

Species

Product code

JAK1 antibody [AF28B1]

M

ELISA, WB

Ms

Hu, Ms, Rt

ab75744

JAK2 (pY1007 + pY1008) antibody [E132]

M

Dot, ICC, IHC-Fr, IHC-P, IP, WB

Rb

Hu, Ms, Rat

ab32101

JAK2 antibody [EPR108(2)]

M

ICC, WB

Rb

Hu, Ms, Rat

ab108596

JAK3 antibody [5H2]

M

ELISA, ICC/IF, WB

Ms

Hu, Ms

ab91206

STAT1 (pY701) antibody [M135]

M

ELISA, ICC, ICC/IF, WB

Ms

Hu, Ms

ab29045

STAT1 antibody

P

ICC, IHC-Fr, IHC-P, IP, WB

Rb

Hu, Ms, Rat

ab2415

STAT2 antibody [Y141]

M

ICC, IHC-P, WB

Rb

Hu, Ms, Rat

ab32367

STAT3 antibody [STAAD22A]

M

ELISA, ICC, WB

Ms

Hu, Ms, Rat

ab50761

STAT3 (pY705) antibody [EP2147Y]

M

ICC, IHC-P, IP, WB

Rb

Hu, Ms, Rat

ab76315

STAT4 antibody [1C2-1C12]

M

ICC/IF, IHC-P, IP, sELISA, WB

Ms

Hu

ab118956

STAT5 (pY694) antibody [E208]

M

ICC/IF, IHC-P, IP, WB

Rb

Hu, Ms

ab32364

STAT5 antibody

P

ELISA, IHC-P, IP, WB

Rb

Hu, Ms, Rat, Cow, Dog

ab97734

STAT6 antibody

P

ICC, ICC/IF, ICC-Fr, IHC-P, IP, WB

Rb

Hu, Ms, Rat

ab44718

TYK2 antibody [EP1127Y]

M

ICC/IF, IHC-P, IP, WB

Rb

Hu, Ms, Rat

ab52645

Many more can be found here.

 

 

PhosphoTracer ELISA Kits detecting both phosphorylated and total targets:

Target 1

Target 2

Target 3

Product code

AKT 1/2/3 (pSer473)

-

-

ab119614

AKT 1/2/3 (pThr308)

-

-

ab119615

AKT 1/2/3 (Total)

-

-

ab119616

AKT 1/2/3 (pSer473)

AKT 1/2/3 (Total)

-

ab119654

AKT 1/2/3 (pThr308)

AKT 1/2/3 (pSer473)

AKT 1/2/3 (Total)

ab119675

ERK 1/2 (pThr202/Tyr204)

-

-

ab119625

ERK 1/2 (Total)

-

-

ab119626

ERK 1/2 (pThr202/Tyr204)

ERK (Total)

-

ab119659

STAT1 (pTyr701)

-

-

ab119649

STAT3 (pTyr705)

-

-

ab119650

STAT3 (Total)

-

-

ab119651

STAT5 (pTyr694/699)

-

-

ab119652

STAT5 (Total)

-

-

ab119653

STAT3 (pTyr705)

STAT3 (Total)

-

ab119672

STAT5 (pTyr694)

STAT5 (Total)

-

ab119673

Look here for more PhosphoTracer ELISA Kits.

 

 

PhosphoTracer ELISA Kits detecting a combination of targets:

Target 1

Target 2

Target 3

Target 4

Product code

ERK 1/2 (pThr202/Tyr204)

p38 MAPK (pThr180/Tyr182)

JNK1/2/3 (pThr183/Tyr185)

-

ab119674

ERK 1/2 (pThr202/Tyr204)

AKT 1/2/3 (pSer473)

CREB1 (pSer133)

-

ab119679

STAT1 (pTyr701)

GAPDH (Total)

-

-

ab119671

STAT1 (pTyr701)

STAT3 (pTyr705)

STAT5 (pTyr694)

-

ab119678

Look here for more PhosphoTracer ELISA Kits.

 

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