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JONATHAN MILNER, CEO
- Mitochondrial ROS metabolism in the heart
- Mitochondrial permeability transition pore
- Mitochondria in vascular smooth muscle
- Therapeutic targets for cardiac disease
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Following the success of the first meeting in the series, Mitochondria and the CNS in health and disease, we are happy to announce we have once again collaborated with the organizing committee to bring you this meeting.
The full program is now available.
Kennedy Lecture Theatre, Institute of Child Health, Guildford Street, London, UK.
Abcam is proud to be working with co-sponsors UCL' Domains for Basic Life Sciences and Neuroscience' and Seahorse Bioscience to bring you this event.
Mitochondrial function and dysfunction are emerging as key players in health and disease involving the vasculature, the heart and in metabolic signalling in adipose tissue and insulin signalling. In this symposium we will bring highlight recent developments in this rapidly growing area. Our guest speakers are world leaders in their fields. Paolo Bernardi has facsinating new data on the possible identity of the permeability transition pore, possibly the single most important common final step in the patwhway to calcium or oxidative stress dependent cell death which he will share with us. Toni Vidal Puig is a key player in understanding metabolic determinants of adipose tissue growth and obesity, at teh interface wbetween mitochondrial metabolism and insulin signalling. We will highlight the breadth of work in the field, from work on calcium signalling in smooth muscle, roles of mitochondrial dysfunction in cardiac hypertrophy, novel data on the importance of mitochondrial shaping proteins as determinants of myocardial injury, and work from Michael Murphy showing the way to newapproaches to measurement of oxidative stress in cells and tissues. It promises to be a most stimulating and engaging meeting for anyone with an interest in mitochondria and cardiovascular disease.
We hope that these symposia will serve as a focal point for interaction in this rapidly expanding and fascinating branch of biomedicine, hope that many people will take the opportunity to come and showcase their work. We look forward to welcoming you to UCL.