Anti-Influenza A Neuraminidase 1 antibody (ab119972)

Overview

  • Product nameAnti-Influenza A Neuraminidase 1 antibody
  • Description
    Rabbit polyclonal to Influenza A Neuraminidase 1
  • Specificityab119972 recognises the neuraminidase protein from seasonal Influenza A/Georgia/20/2006 (H1N1) (Genbank accession no. ACA33620)
  • Tested applicationsSuitable for: ELISAmore details
  • Species reactivity
    Reacts with: Influenza A
  • Immunogen

    Synthetic peptide corresponding to the Neuraminidase protein from seasonal Influenza A/Georgia/20/2006 (H1N1) (Genbank accession no. ACA33620)

Properties

Applications

Our Abpromise guarantee covers the use of ab119972 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA Use at an assay dependent dilution.

Target

  • RelevanceInfluenza A virus is a major public health threat, killing more than 30,000 people per year in the USA (1). Novel influenza virus strains emerge periodically to which humans have little or no immunity, resulting in devastating pandemics. Influenza A can exist in a variety of animals; however it is in birds that all subtypes can be found (2). These subtypes are classified based on the combination of the virus coat glycoproteins hemagglutinin (HA) and neuraminidase (NA) subtypes. During 1997, an H5N1 avian influenza virus was determined to be the cause of death in 6 of 18 infected patients in Hong Kong (3). There was some evidence of human to human spread of this virus, but it is thought that the transmission efficiency was fairly low (4). Although it has been known that cleavage site and glycosylation patterns of the HA protein play important roles in determining the pathogenicity of H5 avian influenza viruses, it has only recently been shown that an additional glycosylation site within the globular head of the NA protein also contributes to the high virulence of the H5N1 virus (5)
  • Cellular localizationVirion and host cell membrane
  • Database links
    • Alternative names
      • Neuraminidase 1 antibody

    References for Anti-Influenza A Neuraminidase 1 antibody (ab119972)

    ab119972 has not yet been referenced specifically in any publications.

    Product Wall

    There are currently no Abreviews or Questions for ab119972.
    Please use the links above to contact us or submit feedback about this product.

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"