Anti-Influenza A Virus antibody (ab20841)
Key features and details
- Goat polyclonal to Influenza A Virus
- Suitable for: ICC/IF, IHC-P
- Reacts with: Influenza A
- Isotype: IgG
Overview
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Product name
Anti-Influenza A Virus antibody
See all Influenza A Virus primary antibodies -
Description
Goat polyclonal to Influenza A Virus -
Host species
Goat -
Tested applications
Suitable for: ICC/IF, IHC-Pmore details -
Species reactivity
Reacts with: Influenza A -
Immunogen
Tissue, cells or virus corresponding to Influenza A Virus. Influenza A virus. Strain: USSR (H1N1).
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
Storage buffer
Preservative: 0.1% Sodium azide
Constituent: 0.0268% PBS -
Concentration information loading...
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Purity
Ion Exchange Chromatography -
Purification notes
>95% pure. Sodium sulfate precipitation and ion-exchange chromatography. -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Recombinant Protein
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab20841 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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ICC/IF |
Use at an assay dependent concentration.
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IHC-P |
1/300.
This product may be used in place of neat antiserum in almost any appropriate antibody-based technique. |
Notes |
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ICC/IF
Use at an assay dependent concentration. |
IHC-P
1/300. This product may be used in place of neat antiserum in almost any appropriate antibody-based technique. |
Target
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Relevance
Influenza A and B are the two types of influenza viruses that cause epidemic human disease. Influenza type C infections cause a mild respiratory illness and are not thought to cause epidemics. Influenza A viruses are further categorized into subtypes on the basis of two surface antigens: hemagglutinin (H) and neuraminidase (N). Strains are also described by geographic origin, strain number and year of isolation. -
Cellular localization
Nuclear -
Database links
- Entrez Gene: 956531 Influenza A
- SwissProt: P03452 Influenza A
- SwissProt: P03466 Influenza A
- SwissProt: P18072 Influenza A
Images
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ab20841 staining Influenza A Virus in reconstructed 1918 H1N1 influenza infected Mouse lung tissue sections by Immunohistochemistry. Tissue was fixed with 10% neutral-buffered formalin and embedded in paraffin. Slides were deparaffinized, rehydrated in water, steam antigen retrieved in pH 6 citrate buffer, and blocked with 3% H2O2. Samples were incubated with primary antibody (1/500) for 1 hour at room temperature. Top - EUK-207 treated mouse, 8 days postinfection, Bottom uninfected mouse control. Brown staining indicates positive staining in cell's cytoplasm and/or nucleus. Cellular debris is also frequently positive.
Protocols
Datasheets and documents
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SDS download
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Datasheet download
References (20)
ab20841 has been referenced in 20 publications.
- Slaine PD et al. Thiopurines activate an antiviral unfolded protein response that blocks influenza A virus glycoprotein accumulation. J Virol N/A:N/A (2021). PubMed: 33762409
- Rahim MMA et al. Defective Influenza A Virus RNA Products Mediate MAVS-Dependent Upregulation of Human Leukocyte Antigen Class I Proteins. J Virol 94:N/A (2020). PubMed: 32321802
- Vazquez-Armendariz AI et al. Multilineage murine stem cells generate complex organoids to model distal lung development and disease. EMBO J 39:e103476 (2020). PubMed: 32985719
- Slaine PD et al. Adaptive Mutations in Influenza A/California/07/2009 Enhance Polymerase Activity and Infectious Virion Production. Viruses 10:N/A (2018). PubMed: 29783694
- Slaine PD et al. Stress Granule-Inducing Eukaryotic Translation Initiation Factor 4A Inhibitors Block Influenza A Virus Replication. Viruses 9:N/A (2017). PubMed: 29258238