Anti-Influenza A Virus Hemagglutinin H5 antibody [B254M] (ab73454)

Overview

  • Product nameAnti-Influenza A Virus Hemagglutinin H5 antibody [B254M]
    See all Influenza A Virus Hemagglutinin H5 primary antibodies
  • Description
    Mouse monoclonal [B254M] to Influenza A Virus Hemagglutinin H5
  • Specificityab73454 is specific for Influenza A Hemagglutinin H5 (Avian H5N1).
  • Tested applicationsSuitable for: Inhibition Assay, Sandwich ELISAmore details
  • Species reactivity
    Reacts with Influenza A Virus.
  • Immunogen

    Purified avian influenza virus type A (H5N1)

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • Storage bufferPreservative: 0.1% Sodium Azide
    Constituents: PBS, pH 7.4
  • Concentration information loading...
  • PurityProtein G purified
  • Purification notesab73454 is >95% pure as determined by SDS-PAGE.
  • ClonalityMonoclonal
  • Clone numberB254M
  • MyelomaSp2/0
  • IsotypeIgG2a
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab73454 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
Inhibition Assay Use at an assay dependent dilution. Hemagglutinin inhibition (HI) test: Use at an assay dependent dilution.
Sandwich ELISA Use at an assay dependent dilution. Can be paired for Sandwich ELISA with Mouse monoclonal [B253M] to Influenza A Virus Hemagglutinin H5 (ab73453). Can be used as detection antibody with recommended pair.

Target

  • RelevanceInfluenza A belongs to the Orthomyxoviridae family, and is a negative sense single-stranded RNA virus which results in respiratory disease. Haemagglutinin is an antigenic glycoprotein which allows viral attachment and entry into the cell. Sixteen subtypes of haemagglutinin (H1-H16) have been described, of which H1, H2 and H3 infect humans. H5 and H7 normally result in avian disease, with some highly pathogenic H5N1 strains causing 100% mortality in poultry. H5N1 has in some cases mutated to infect humans, with 60% mortality. Haemagglutinin is one of the most medically relevant antigens on influenza as it is a target for antiviral drugs and antibodies.
  • Alternative names
    • H5HA antibody
    • Hemagglutinin 5 antibody

References for Anti-Influenza A Virus Hemagglutinin H5 antibody [B254M] (ab73454)

ab73454 has not yet been referenced specifically in any publications.

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Thank you for your enquiry.

I have contacted the originators of these antibodies, who have kindly provided the following testing results from various Influenza A virus strains with these antibodies:

ab59166 Influenza A Virus Hemag...

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Thank you for contacting us.

We do not have monoclonal antibodies avialable to Solomon Island strain.

We however have antibodies against H1N1 influenza proteinsrelated todifferent strains. Please find attached the list and select t...

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Thank you for your enquiry regarding ab73453, ab73454 and ab73456. The immunogen used to develop ab73453, ab73454 and ab73456 was an analog to A/chick/Scotland/72. The exact strain used is not available. Following are Influenza A strains tested ...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"