Anti-Influenza A Virus M2 Protein antibody (ab94925)


  • Product nameAnti-Influenza A Virus M2 Protein antibody
    See all Influenza A Virus M2 Protein primary antibodies
  • Description
    Rabbit polyclonal to Influenza A Virus M2 Protein
  • Specificityab94925 detects Influenza A Virus M2 Protein. It may crossreact with M2 protein from other strains of influenza.
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Other
  • Immunogen

    A 13 amino acid peptide from the N terminus of Influenza A Virus M2 Protein.



Our Abpromise guarantee covers the use of ab94925 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use at an assay dependent dilution. Predicted molecular weight: 11 kDa.


  • RelevanceThe Matrix protein M2 forms a protons channel. When the environmental pH is lower than a threshold, the M2 channel is activated and selectively transports protons accross the membrane from the extracellular side to the cytoplasmic side. It is crucial for the uncoating process. When the virion is internalized into the endosome the channel can acidify the virion interior, promoting the dissociation of the viral matrix protein (M1) from the ribonucleoprotein (RNP) thus allowing the transport of the RNP from the virion into the cell’s nucleus. For some influenza virus subtypes, the M2 channel can elevate the intravesicular pH of the trans Golgi network, preventing the viral protein haemagglutinin, which is transported to the cell surface through the trans Golgi network, from incorrect maturation in an otherwise low pH environment.
  • Cellular localizationVirion membrane. Apical cell membrane; Single-pass type III membrane protein.
  • Alternative names
    • Influenza A virus matrix protein M2 antibody
    • M antibody
    • M2 antibody
    • Matrix protein 2 antibody
    • Membrane ion channel M2 antibody
    • Membrane protein M2 antibody
    • Proton channel protein M2 antibody
    see all

References for Anti-Influenza A Virus M2 Protein antibody (ab94925)

ab94925 has not yet been referenced specifically in any publications.

Product Wall

Abcam has not validated the combination of species/application used in this Abreview.
Application ELISA
Sample A/Sw/SK/2001 (H1N1) influenza Purified protein (Purified inactivated human H3N2 influenza virus)
Specification Purified inactivated human H3N2 influenza virus
Type Indirect

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Verified customer

Submitted Nov 02 2016

Thank you for your enquiry and interest in our products.
There is 92.31% homology between the immunogen used for ab94925 (Anti-Influenza A Virus M2 Protein antibody) and ACP44185 - EMBL: Matrix protein 2 - Influenza A virus (A/California/07/2009(H...

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Thank you for your enquiry.

The immunogens used to produce ab94925 and ab56086 consist of a small 15-20 amino acid peptide from Influenza A virus M2 protein. These peptides are not His tagged.

I hope this is helpful. Please contact ...

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Following my colleague's email sent on Friday 23rd of December (CCE 3385949), we have been informed that there is 84% homology between the immunogen for ab94925 ( and the customer's sequence: [******* ****]. I hope this informatio...

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Thank you very much for your inquiry. I have contacted the laboratory for information on the ab5416. However the laboratory has not tested this antibody neither on your strain. I did a sequence alignement of the immunogen and your sequence. Please see ...

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