Anti-Influenza A Virus Nucleoprotein antibody (ab91648)

Overview

  • Product nameAnti-Influenza A Virus Nucleoprotein antibody
    See all Influenza A Virus Nucleoprotein primary antibodies
  • Description
    Rabbit polyclonal to Influenza A Virus Nucleoprotein
  • Specificityab91648 is specific for the seasonal Influenza A Virus Nucleoprotein and will not recognize the corresponding Nucleoprotein sequence from the swine origin H1N1 influenza (A/California/14/2009 (H1N1)).
  • Tested applicationsSuitable for: ELISAmore details
  • Species reactivity
    Influenza A virus
  • Immunogen

    A synthetic peptide from the Seasonal Influenza A Virus Nucleoprotein (H1N1) (Genbank accession AFK14863).

Properties

Applications

Our Abpromise guarantee covers the use of ab91648 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA
  • Application notesELISA: Use at a concentration of 1 µg/ml.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • RelevanceThe nucleoprotein (NP) of Influenza virus encapsulates the negative strand of the viral RNA and is essential for replicative transcription. It may also be involved in other essential functions throughout the virus life cycle. As well as binding ssRNA, NP is able to self associate to form large oligomeric complexes. NP is able to interact with a variety of other macromolecules of both viral and cellular origins. It binds the PB1 and PB2 subunits of the polymerase and the matrix protein M1. "NP has also been shown to interact with at least four cellular polypeptide families: nuclear import receptors of the importin class, filamentous (F) actin, the nuclear export receptor CRM1 and a DEAD box helicase BAT1/UAP56" (Portela et al 2002).
    • Cellular localizationHost cell nucleus
    • Alternative names
      • Common flu NP antibody
      • Influenza A virus NP antibody
      • NP antibody
      • Nucleocapsid protein antibody
      • Nucleoprotein antibody
      • Protein N antibody
      • Seasonal Influenza A (H1N1) Nucleocapsid Protein antibody
      see all

    Anti-Influenza A Virus Nucleoprotein antibody images

    • ab91648, at a concentration of 1 µg/ml, detects seasonal Influenza A Virus Nucleoprotein by Elisa. It does not recognize the corresponding Nucleoprotein sequence from the swine origin H1N1 influenza (A/California/14/2009 (H1N1)). The blocking and corresponding peptides were used at 60, 10, 2 and 0 ng/ml.

    References for Anti-Influenza A Virus Nucleoprotein antibody (ab91648)

    ab91648 has not yet been referenced specifically in any publications.

    Product Wall

    The sequence homology between the immunogen for ab91648 and your target is around 62.5%. Based on this, ab91648 probably will not cross-react with your target.

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"