Anti-Influenza A Virus Nucleoprotein antibody (ab91648)
Key features and details
- Rabbit polyclonal to Influenza A Virus Nucleoprotein
- Suitable for: ELISA
- Reacts with: Influenza A
- Isotype: IgG
Overview
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Product name
Anti-Influenza A Virus Nucleoprotein antibody
See all Influenza A Virus Nucleoprotein primary antibodies -
Description
Rabbit polyclonal to Influenza A Virus Nucleoprotein -
Host species
Rabbit -
Specificity
ab91648 is specific for the seasonal Influenza A Virus Nucleoprotein and will not recognize the corresponding Nucleoprotein sequence from the swine origin H1N1 influenza (A/California/14/2009 (H1N1)). -
Tested applications
Suitable for: ELISAmore details -
Species reactivity
Reacts with: Influenza A -
Immunogen
A synthetic peptide from the Seasonal Influenza A Virus Nucleoprotein (H1N1) (Genbank accession AFK14863).
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C. -
Storage buffer
pH: 7.2
Preservative: 0.02% Sodium azide
Constituent: PBS -
Concentration information loading...
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Purity
Immunogen affinity purified -
Purification notes
Affinity chromatography purified via peptide column. -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Recombinant Protein
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab91648 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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ELISA |
Notes |
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Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
Target
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Relevance
The nucleoprotein (NP) of Influenza virus encapsulates the negative strand of the viral RNA and is essential for replicative transcription. It may also be involved in other essential functions throughout the virus life cycle. As well as binding ssRNA, NP is able to self associate to form large oligomeric complexes. NP is able to interact with a variety of other macromolecules of both viral and cellular origins. It binds the PB1 and PB2 subunits of the polymerase and the matrix protein M1. "NP has also been shown to interact with at least four cellular polypeptide families: nuclear import receptors of the importin class, filamentous (F) actin, the nuclear export receptor CRM1 and a DEAD box helicase BAT1/UAP56" (Portela et al 2002). -
Cellular localization
Host cell nucleus -
Database links
- Entrez Gene: 956531 Influenza A
- SwissProt: P03466 Influenza A
- SwissProt: P69291 Influenza A
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Alternative names
- Common flu NP antibody
- Influenza A virus NP antibody
- NP antibody
see all
Images
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ab91648, at a concentration of 1 µg/ml, detects seasonal Influenza A Virus Nucleoprotein by Elisa. It does not recognize the corresponding Nucleoprotein sequence from the swine origin H1N1 influenza (A/California/14/2009 (H1N1)). The blocking and corresponding peptides were used at 60, 10, 2 and 0 ng/ml.
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
Datasheets and documents
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SDS download
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Datasheet download
References (1)
ab91648 has been referenced in 1 publication.
- Motawea HKB et al. Human Placenta Expresses a2-Adrenergic Receptors and May Be Implicated in Pathogenesis of Preeclampsia and Fetal Growth Restriction. Am J Pathol 188:2774-2785 (2018). PubMed: 30273604