Anti-ING1 antibody (Biotin) - Aminoterminal end (ab55883)

Overview

  • Product name
    Anti-ING1 antibody (Biotin) - Aminoterminal end
    See all ING1 primary antibodies
  • Description
    Rabbit polyclonal to ING1 - Aminoterminal end (Biotin)
  • Conjugation
    Biotin
  • Specificity
    ab55883 recognizes p33 ING1. It does not cross react with other members of the ING family.
  • Tested applications
    Suitable for: WB, ELISAmore details
  • Species reactivity
    Reacts with: Recombinant fragment
    Predicted to work with: Mouse, Human
  • Immunogen

    Mouse p33 ING1 N-terminal synthetic peptide conjugated to KLH.

  • General notes

    Acylation of primary amine with active ester of biotin (NHS-activated d-biotin).

Properties

Applications

Our Abpromise guarantee covers the use of ab55883 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 47 kDa. This antibody has been tested in Western blot against the recombinant peptide used as an immunogen. We have no data on detection of endogenous protein.
ELISA Use a concentration of 0.25 µg/ml.

Target

  • Function
    Cooperates with p53/TP53 in the negative regulatory pathway of cell growth by modulating p53-dependent transcriptional activation. Implicated as a tumor suppressor gene.
  • Tissue specificity
    Isoform 2 was expressed in all normal tissues and cells examined, as well as in all breast cancer and melanoma cell lines examined. Isoform 3 was expressed in testis, liver, and kidney, weakly expressed in colon and brain and not expressed in breast and cultured melanocytes. Isoform 4 was highly expressed in testis and weakly expressed in brain, but not expressed in breast, colon, kidney, melanocytes, breast cancer or melanoma cell lines.
  • Involvement in disease
    Defects in ING1 are a cause of head and neck squamous cell carcinomas (HNSCC) [MIM:275355]; also known as squamous cell carcinoma of the head and neck.
  • Sequence similarities
    Belongs to the ING family.
    Contains 1 PHD-type zinc finger.
  • Cellular localization
    Nucleus.
  • Information by UniProt
  • Database links
  • Alternative names
    • 2610028J21Rik antibody
    • AA407184 antibody
    • AI875420 antibody
    • Growth inhibitor ING 1 antibody
    • Growth inhibitor ING1 antibody
    • Growth inhibitory protein ING 1 antibody
    • Growth inhibitory protein ING1 antibody
    • Homo sapiens growth inhibitor p33ING1 (ING1) mRNA, complete cds antibody
    • ING 1 antibody
    • Ing1 antibody
    • ING1_HUMAN antibody
    • Inhibitor of growth 1 antibody
    • Inhibitor of growth family member 1 antibody
    • Inhibitor of growth protein 1 antibody
    • mING1h antibody
    • OTTHUMP00000018703 antibody
    • OTTHUMP00000018704 antibody
    • OTTHUMP00000018705 antibody
    • OTTHUMP00000018706 antibody
    • p24ING1c antibody
    • p33 antibody
    • p33 ING1 antibody
    • p33ING1 antibody
    • p33ING1b antibody
    • p33ING1c antibody
    • p37Ing1b antibody
    • p47 antibody
    • p47ING1a antibody
    • Tumor suppressor ING 1 antibody
    • Tumor suppressor ING1 antibody
    see all

References

ab55883 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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