Recombinant
RabMAb

Anti-ING3 antibody [EPR3808] (ab108610)

Overview

  • Product name
    Anti-ING3 antibody [EPR3808]
    See all ING3 primary antibodies
  • Description
    Rabbit monoclonal [EPR3808] to ING3
  • Specificity
    The immunogen for this product has 100% homology with ING2.
  • Tested applications
    Suitable for: WB, IPmore details
    Unsuitable for: Flow Cyt,ICC or IHC-P
  • Species reactivity
    Reacts with: Mouse, Rat, Human
  • Immunogen

    A synthetic peptide corresponding to residues in Human ING3.

  • Positive control
    • Human fetal brain, heart, and fetal kidney lysates; Mouse brain, heart and kidney lysates; Rat brain and heart lysates.
  • General notes

    This product is a recombinant rabbit monoclonal antibody.

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents

Properties

Applications

Our Abpromise guarantee covers the use of ab108610 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000 - 1/10000. Detects a band of approximately 50 kDa (predicted molecular weight: 47 kDa).
IP 1/10 - 1/100.
  • Application notes
    Is unsuitable for Flow Cyt,ICC or IHC-P.
  • Target

    • Relevance
      Function: Component of the NuA4 histone acetyltransferase (HAT) complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. NuA4 may also play a direct role in DNA repair when directly recruited to sites of DNA damage. Component of a SWR1-like complex that specifically mediates the removal of histone H2A.Z/H2AFZ from the nucleosome. Tissue specificity: Expressed in brain, heart, kidney, liver, lung, ovaries, placenta, prostate, skeletal muscle, small intestine, spleen, testis and thymus. Disease: Squamous cell carcinoma of the head and neck Similarity: Belongs to the ING family. Contains 1 PHD-type zinc finger. Domain: The PHD-type zinc finger mediates the binding to H3K4me3.
    • Cellular localization
      Nuclear
    • Database links
    • Alternative names
      • 1300013A07Rik antibody
      • Eaf 4 antibody
      • Eaf4 antibody
      • FLJ20089 antibody
      • ING 2 antibody
      • ING 3 antibody
      • ING2 antibody
      • ING3 antibody
      • ING3_HUMAN antibody
      • Inhibitor of growth family member 3 antibody
      • Inhibitor of growth protein 3 antibody
      • MEAF4 antibody
      • p47 ING 3 antibody
      • p47 ING3 antibody
      • p47 regulator protein antibody
      • p47ING3 antibody
      • p47ING3 protein antibody
      see all

    Anti-ING3 antibody [EPR3808] images

    • All lanes : Anti-ING3 antibody [EPR3808] (ab108610) at 1/1000 dilution

      Lane 1 : Humna fetal brain lysate
      Lane 2 : Human heart lysate
      Lane 3 : Human fetal kidney lysate

      Lysates/proteins at 10 µg per lane.


      Predicted band size : 47 kDa
      Observed band size : 50 kDa (why is the actual band size different from the predicted?)
    • All lanes : Anti-ING3 antibody [EPR3808] (ab108610) at 1/1000 dilution

      Lane 1 : Mouse brain lysate
      Lane 2 : Mouse heart lysate
      Lane 3 : Mouse kidney lysate
      Lane 4 : Rat brain lysate
      Lane 5 : Rat heart lysate

      Lysates/proteins at 10 µg per lane.


      Predicted band size : 47 kDa

    References for Anti-ING3 antibody [EPR3808] (ab108610)

    ab108610 has not yet been referenced specifically in any publications.

    Product Wall

    There are currently no Abreviews or Questions for ab108610.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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