Overview

  • Product nameAnti-ING3 antibody [EPR3808]
    See all ING3 primary antibodies
  • Description
    Rabbit monoclonal [EPR3808] to ING3
  • SpecificityThe immunogen for this product has 100% homology with ING2.
  • Tested applicationsSuitable for: WB, IPmore details
    Unsuitable for: Flow Cyt,ICC or IHC-P
  • Species reactivity
    Reacts with: Mouse, Rat, Human
  • Immunogen

    A synthetic peptide corresponding to residues in Human ING3.

  • Positive control
    • Human fetal brain, heart, and fetal kidney lysates; Mouse brain, heart and kidney lysates; Rat brain and heart lysates.
  • General notes

    This product is a recombinant rabbit monoclonal antibody.

    Produced using Abcam’s RabMAb® technology. RabMAb® technology is covered by the following U.S. Patents, No. 5,675,063 and/or 7,429,487.

Properties

Applications

Our Abpromise guarantee covers the use of ab108610 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000 - 1/10000. Detects a band of approximately 50 kDa (predicted molecular weight: 47 kDa).
IP 1/10 - 1/100.
  • Application notesIs unsuitable for Flow Cyt,ICC or IHC-P.
  • Target

    • RelevanceING3 belongs to a family of proteins containing the plant homeodomain (PHD) finger, which includes transcription factors and proteins that regulate chromatin structure. ING3 is a component of the NuA4 histone acetyltransferase (HAT) complex and can activate p53 trans-activated promoters, including promoters of p21/waf1 and bax. Overexpression of ING3 has been shown to inhibit cell growth and induce apoptosis. Allelic loss and reduced expression of the ING3 gene were detected in head and neck cancers.
    • Cellular localizationNuclear
    • Database links
    • Alternative names
      • 1300013A07Rik antibody
      • Eaf 4 antibody
      • Eaf4 antibody
      • FLJ20089 antibody
      • ING 2 antibody
      • ING 3 antibody
      • ING2 antibody
      • Inhibitor of growth family member 3 antibody
      • Inhibitor of growth protein 3 antibody
      • MEAF4 antibody
      • p47 ING 3 antibody
      • p47 ING3 antibody
      • p47 regulator protein antibody
      • p47ING3 antibody
      • p47ING3 protein antibody
      see all

    Anti-ING3 antibody [EPR3808] images

    • All lanes : Anti-ING3 antibody [EPR3808] (ab108610) at 1/1000 dilution

      Lane 1 : Humna fetal brain lysate
      Lane 2 : Human heart lysate
      Lane 3 : Human fetal kidney lysate

      Lysates/proteins at 10 µg per lane.


      Predicted band size : 47 kDa
      Observed band size : 50 kDa (why is the actual band size different from the predicted?)
    • All lanes : Anti-ING3 antibody [EPR3808] (ab108610) at 1/1000 dilution

      Lane 1 : Mouse brain lysate
      Lane 2 : Mouse heart lysate
      Lane 3 : Mouse kidney lysate
      Lane 4 : Rat brain lysate
      Lane 5 : Rat heart lysate

      Lysates/proteins at 10 µg per lane.


      Predicted band size : 47 kDa

    References for Anti-ING3 antibody [EPR3808] (ab108610)

    ab108610 has not yet been referenced specifically in any publications.

    Product Wall

    There are currently no Abreviews or Questions for ab108610.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"