Overview

  • Product nameAnti-ING4 antibody [EP3804]
    See all ING4 primary antibodies
  • Description
    Rabbit monoclonal [EP3804] to ING4
  • Tested applicationsSuitable for: WB, IPmore details
    Unsuitable for: Flow Cyt,ICC or IHC-P
  • Species reactivity
    Reacts with: Mouse, Rat, Human
  • Immunogen

    Synthetic peptide (the amino acid sequence is considered to be commercially sensitive)

  • Positive control
    • 293T, T47-D, Jurkat, C6, Raw264.7 and PC-12 cell lysates
  • General notes

    This product is a recombinant rabbit monoclonal antibody.

     

    Produced using Abcam’s RabMAb® technology. RabMAb® technology is covered by the following U.S. Patents, No. 5,675,063 and/or 7,429,487.

Properties

Applications

Our Abpromise guarantee covers the use of ab108621 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000 - 1/10000. Detects a band of approximately 29 kDa (predicted molecular weight: 29 kDa).Can be blocked with Human ING4 peptide (ab197784).
IP 1/10 - 1/100.
  • Application notesIs unsuitable for Flow Cyt,ICC or IHC-P.
  • Target

    • FunctionComponent of the HBO1 complex which has a histone H4-specific acetyltransferase activity, a reduced activity toward histone H3 and is responsible for the bulk of histone H4 acetylation in vivo. Through chromatin acetylation it may function in DNA replication. May inhibit tumor progression by modulating the transcriptional output of signaling pathways which regulate cell proliferation. Can suppress brain tumor angiogenesis through transcriptional repression of RELA/NFKB3 target genes when complexed with RELA. May also specifically suppress loss of contact inhibition elicited by activated oncogenes such as MYC. Represses hypoxia inducible factor's (HIF) activity by interacting with HIF prolyl hydroxylase 2 (EGLN1).
    • Sequence similaritiesBelongs to the ING family.
      Contains 1 PHD-type zinc finger.
    • Cellular localizationNucleus.
    • Information by UniProt
    • Database links
    • Alternative names
      • Brain my036 protein antibody
      • Candidate tumor suppressor p33 ING 1 homolog antibody
      • Candidate tumor suppressor p33 ING1 homolog antibody
      • D6Wsu147e antibody
      • D6Xrf92 antibody
      • ING 1 like protein antibody
      • ING 4 antibody
      • ING1 like protein antibody
      • ING4 antibody
      • ING4_HUMAN antibody
      • Inhibitor of growth family member 4 antibody
      • Inhibitor of growth family member 4 long isoform antibody
      • Inhibitor of growth protein 4 antibody
      • MGC12557 antibody
      • my036 antibody
      • p29 ING 4 antibody
      • p29 ING4 antibody
      • p29ING4 antibody
      see all

    Anti-ING4 antibody [EP3804] images

    • All lanes : Anti-ING4 antibody [EP3804] (ab108621) at 1/1000 dilution

      Lane 1 : 293T cell lysate
      Lane 2 : T47-D cell lysate
      Lane 3 : Jurkat cell lysate

      Lysates/proteins at 10 µg per lane.


      Predicted band size : 29 kDa
    • All lanes : Anti-ING4 antibody [EP3804] (ab108621) at 1/1000 dilution

      Lane 1 : C6 cell lysate
      Lane 2 : Raw264.7 cell lysate
      Lane 3 : PC-12 cell lysate

      Lysates/proteins at 10 µg per lane.


      Predicted band size : 29 kDa

    References for Anti-ING4 antibody [EP3804] (ab108621)

    ab108621 has not yet been referenced specifically in any publications.

    Product Wall

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"