Anti-Inhibin alpha antibody, prediluted (ab74323)


  • Product nameAnti-Inhibin alpha antibody, prediluted
    See all Inhibin alpha primary antibodies
  • Description
    Rabbit polyclonal to Inhibin alpha, prediluted
  • Tested applicationsSuitable for: IHC-P, WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide from the N-terminal of human Inhibin alpha

  • Positive control
    • Testis.


Associated products


Our Abpromise guarantee covers the use of ab74323 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/1. Perform heat mediated antigen retrieval before commencing with IHC staining protocol.
WB Use at an assay dependent concentration.


  • FunctionInhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins.
  • Tissue specificityOriginally found in ovary (granulosa cells) and testis (Sertoli cells), but widely distributed in many tissues including brain and placenta. In adrenal cortex expression is limited to the zona reticularis and the innermost zona fasciculata in the normal gland, extending centripetally into the zona fasciculata in hyperplasia. Also found in adrenocortical tumors. Also expressed in prostate epithelium of benign prostatic hyperplasia, in regions of basal cell hyperplasia and in nonmalignant regions of high grade prostate cancer. Only circulating inhibin B is found in male, whereas circulating inhibins A and B are found in female.
  • Sequence similaritiesBelongs to the TGF-beta family.
  • Post-translational
    Proteolytic processing yields a number of bioactive forms. The 20/23 kDa forms consist solely of the mature alpha chain, the 26/29 kDa forms consist of the most N-terminal propeptide linked through a disulfide bond to the mature alpha chain, the 50/53 kDa forms encompass the entire proprotein. Each type can be furthermore either mono- or diglycosylated, causing the mass difference.
  • Cellular localizationSecreted.
  • Information by UniProt
  • Database links
  • Alternative names
    • A inhibin subunit antibody
    • A inhibin subunit precursor antibody
    • IHA antibody
    • inhA antibody
    • INHA_HUMAN antibody
    • Inhibin alpha chain antibody
    • Inhibin alpha chain precursor antibody
    • Inhibin alpha subunit antibody
    see all

Anti-Inhibin alpha antibody, prediluted images

  • Staining of formalin-fixed, paraffin-embedded human testis tissue with ab74323.
  • Anti-Inhibin alpha antibody, prediluted (ab74323) at 1/25 dilution + lysate prepared from HeLa cells

References for Anti-Inhibin alpha antibody, prediluted (ab74323)

ab74323 has not yet been referenced specifically in any publications.

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