Recombinant full length protein - A chain beta 1 (Human).
The activins and inhibins are glycoproteins that belong to the transforming growth factor beta like (TGF b like) superfamily of growth factors. These factors transduce their signals by interacting with two types of receptor serine / threonine kinases that phosphorylate members of the SMAD family of transcription factors, thereby promoting their nuclear localization. SMAD 2 and 3 can form a complex with the activin receptor in a ligand dependent manner. This complex formation is rapid but also transient. Indeed, soon after their association with the activin receptor, SMAD 2 and SMAD 3 are released into the cytoplasm where they interact with the common partner SMAD 4.
Our Abpromise guarantee covers the use of ab4241 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|ELISA||Use at an assay dependent concentration.|
ab4241 has not yet been referenced specifically in any publications.