FunctionInhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins.
Sequence similaritiesBelongs to the TGF-beta family.
All lanes : Anti-Inhibin beta A antibody (ab97705) at 1/1000 dilution
Lane 1 : H1299 whole cell lysate Lane 2 : HeLa S3 whole cell lysate Lane 3 : HepG2 whole cell lysate
Lysates/proteins at 30 µg per lane.
Predicted band size : 47 kDa
Immunocytochemistry/ Immunofluorescence - Inhibin beta A antibody (ab97705)
ab97705, at 1/200 dilution, staining Inhibin beta A in paraformaldehyde-fixed HeLa cells by Immunofluorescence. Lower image is merged with DNA probe.
References for Anti-Inhibin beta A antibody (ab97705)
This product has been referenced in:
Arai KY et al. IL-1beta stimulates activin betaA mRNA expression in human skin fibroblasts through the MAPK pathways, the nuclear factor-kappaB pathway, and prostaglandin E2. Endocrinology152:3779-90 (2011).
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