Overview

  • Product name
    Anti-Inhibin beta A antibody
    See all Inhibin beta A primary antibodies
  • Description
    Rabbit polyclonal to Inhibin beta A
  • Tested applications
    Suitable for: WB, ICC/IFmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide, corresponding to a sequence within amino acids 362-423 (SGSSLSFHST VINHYRMRGH SPFANLKSCC VPTKLRPMSM LYYDDGQNII KKDIQNMIVE EC) of Human Inhibin beta A (NP_002183).

  • Positive control
    • H1299, HeLa S3 and HepG2 whole cell lysates; HeLa cells; 293T, A431, MOLT4 and Raji cell lines.

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • Storage buffer
    Preservative: 0.01% Thimerosal (merthiolate)
    Constituents: 10% Glycerol, 0.1M Tris, 0.1M Glycine, pH 7.0
  • Concentration information loading...
  • Purity
    Immunogen affinity purified
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab97705 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 47 kDa.
ICC/IF 1/100 - 1/200.

Target

  • Function
    Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins.
  • Sequence similarities
    Belongs to the TGF-beta family.
  • Cellular localization
    Secreted.
  • Information by UniProt
  • Database links
  • Alternative names
    • Activin beta-A chain antibody
    • EDF antibody
    • Erythroid differentiation factor antibody
    • Erythroid differentiation protein antibody
    • Follicle stimulating hormone releasing protein antibody
    • FRP antibody
    • FSH releasing protein antibody
    • INHBA antibody
    • INHBA_HUMAN antibody
    • Inhibin beta A chain antibody
    • Inhibin beta A subunit antibody
    • Inhibin, beta 1 antibody
    • Inhibin, beta A (activin A, activin AB alpha polypeptide) antibody
    see all

Images

  • All lanes : Anti-Inhibin beta A antibody (ab97705) at 1/1000 dilution

    Lane 1 : H1299 whole cell lysate
    Lane 2 : HeLa S3 whole cell lysate
    Lane 3 : HepG2 whole cell lysate

    Lysates/proteins at 30 µg per lane.


    Predicted band size : 47 kDa
  • ab97705, at 1/200 dilution, staining Inhibin beta A in paraformaldehyde-fixed HeLa cells by Immunofluorescence. Lower image is merged with DNA probe.

References

This product has been referenced in:
  • Arai KY  et al. IL-1beta stimulates activin betaA mRNA expression in human skin fibroblasts through the MAPK pathways, the nuclear factor-kappaB pathway, and prostaglandin E2. Endocrinology 152:3779-90 (2011). WB ; Human . Read more (PubMed: 21828177) »

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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