Recombinant
RabMAb

Anti-INSC antibody [EPR13470] (ab181210)

Overview

  • Product name
    Anti-INSC antibody [EPR13470]
    See all INSC primary antibodies
  • Description
    Rabbit monoclonal [EPR13470] to INSC
  • Host species
    Rabbit
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant fragment within Human INSC aa 400-550. The exact sequence is proprietary.
    Database link: Q1MX18

  • Positive control
    • 293, Human fetal kidney and fetal liver lysates.
  • General notes

     

     

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents

    This product is a recombinant rabbit monoclonal antibody.

Properties

Applications

Our Abpromise guarantee covers the use of ab181210 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000. Detects a band of approximately 63 kDa (predicted molecular weight: 63 kDa).

Target

  • Function
    May function as an adapter linking the Par3 complex to the GPSM1/GPSM2 complex. Involved in spindle orientation during mitosis it may regulate cell proliferation and differentiation in the developing nervous system. May play a role in the asymmetric division of fibroblasts and participate in the process of stratification of the squamous epithelium.
  • Tissue specificity
    Isoform 1 is expressed in various tissues with stronger expression in liver, kidney and small intestine. Isoform 2 is abundantly expressed in small intestine and to a lower extent in lung and pancreas.
  • Developmental stage
    Expressed in fetal cochlea.
  • Cellular localization
    Cytoplasm. Localizes to the apical cortex of mitotic epidermal cells and to the apical side of neuronal progenitor cells.
  • Information by UniProt
  • Database links
  • Alternative names
    • Insc antibody
    • INSC_HUMAN antibody
    • Inscuteable homolog (Drosophila) antibody
    • Protein inscuteable homolog antibody

Images

  • All lanes : Anti-INSC antibody [EPR13470] (ab181210) at 1/1000 dilution

    Lane 1 : Human fetal liver lysate
    Lane 2 : 293 lysate

    Lysates/proteins at 10 µg per lane.

    Secondary
    All lanes : Goat Anti-Rabbit IgG H&L (HRP) (ab136636) at 1/500 dilution

    Predicted band size: 63 kDa

  • Anti-INSC antibody [EPR13470] (ab181210) at 1/1000 dilution + Human fetal kidney lysate at 20 µg

    Secondary
    Goat Anti-Rabbit IgG H&L (HRP) (ab136636) at 1/500 dilution

    Predicted band size: 63 kDa

References

ab181210 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab181210.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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