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ab7842 has been referenced in 84 publications.

  • Singhal G  et al. Fibroblast Growth Factor 21 (FGF21) Protects against High Fat Diet Induced Inflammation and Islet Hyperplasia in Pancreas. PLoS One 11:e0148252 (2016). Mouse . PubMed: 26872145
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  • Huang C  et al. Endogenous GLP-1 as a key self-defense molecule against lipotoxicity in pancreatic islets. Int J Mol Med 36:173-85 (2015). IHC-P ; Mouse . PubMed: 25976560
  • Cheung K  et al. CD31 signals confer immune privilege to the vascular endothelium. Proc Natl Acad Sci U S A 112:E5815-24 (2015). IHC-P ; Mouse . PubMed: 26392551
  • Coelho PA  et al. Over-expression of Plk4 induces centrosome amplification, loss of primary cilia and associated tissue hyperplasia in the mouse. Open Biol 5:N/A (2015). PubMed: 26701933
  • Razavi R  et al. Diabetes enhances the proliferation of adult pancreatic multipotent progenitor cells and biases their differentiation to more ß-cell production. Diabetes 64:1311-23 (2015). PubMed: 25392245
  • Raum JC  et al. Tshz1 Regulates Pancreatic ß-Cell Maturation. Diabetes 64:2905-14 (2015). Mouse . PubMed: 25918232
  • Tamura K  et al. Liraglutide improves pancreatic Beta cell mass and function in alloxan-induced diabetic mice. PLoS One 10:e0126003 (2015). IHC-P ; Mouse . PubMed: 25938469
  • Johansson U  et al. Pancreatic Islet Survival and Engraftment Is Promoted by Culture on Functionalized Spider Silk Matrices. PLoS One 10:e0130169 (2015). ICC, IHC ; Human . PubMed: 26090859
  • Hoelen H  et al. Proteasomal Degradation of Proinsulin Requires Derlin-2, HRD1 and p97. PLoS One 10:e0128206 (2015). IP ; Human . PubMed: 26107514
  • Torkko JM  et al. Stability of proICA512/IA-2 and its targeting to insulin secretory granules require ß4-sheet-mediated dimerization of its ectodomain in the endoplasmic reticulum. Mol Cell Biol 35:914-27 (2015). PubMed: 25561468
  • Maneva-Radicheva L  et al. Autoimmune diabetes is suppressed by treatment with recombinant human tissue Kallikrein-1. PLoS One 9:e107213 (2014). IHC-Fr ; Mouse . PubMed: 25259810
  • Omar BA  et al. Fibroblast growth factor 21 (FGF21) and glucagon-like peptide 1 contribute to diabetes resistance in glucagon receptor-deficient mice. Diabetes 63:101-10 (2014). Mouse . PubMed: 24062250
  • Meyer Zu Schwabedissen HE  et al. OATP1B3 is expressed in pancreatic ß-islet cells and enhances the insulinotropic effect of the sulfonylurea derivative glibenclamide. Diabetes 63:775-84 (2014). Mouse . PubMed: 24150606
  • Fritz JM  et al. Deficiency of the BiP cochaperone ERdj4 causes constitutive endoplasmic reticulum stress and metabolic defects. Mol Biol Cell 25:431-40 (2014). IP, IHC-P ; Mouse . PubMed: 24336520
  • Patel MS  et al. Beta cell specific pyruvate dehydrogenase alpha gene deletion results in a reduced islet number and ß-cell mass postnatally. Exp Biol Med (Maywood) N/A:N/A (2014). Mouse . PubMed: 24845368
  • Jaeckle Santos LJ  et al. Neutralizing Th2 inflammation in neonatal islets prevents ß-cell failure in adult IUGR rats. Diabetes 63:1672-84 (2014). PubMed: 24408314
  • Gerdes JM  et al. Ciliary dysfunction impairs beta-cell insulin secretion and promotes development of type 2 diabetes in rodents. Nat Commun 5:5308 (2014). PubMed: 25374274
  • Terami N  et al. Long-Term Treatment with the Sodium Glucose Cotransporter 2 Inhibitor, Dapagliflozin, Ameliorates Glucose Homeostasis and Diabetic Nephropathy in db/db Mice. PLoS One 9:e100777 (2014). IHC-P ; Mouse . PubMed: 24960177
  • Espitia Pinzon N  et al. Tissue Transglutaminase in Marmoset Experimental Multiple Sclerosis: Discrepancy between White and Grey Matter. PLoS One 9:e100574 (2014). IHC-P ; Marmoset (common) . PubMed: 24959868
  • Ohki R  et al. PHLDA3 is a novel tumor suppressor of pancreatic neuroendocrine tumors. Proc Natl Acad Sci U S A 111:E2404-13 (2014). PubMed: 24912192
  • Wang R  et al. Perk gene dosage regulates glucose homeostasis by modulating pancreatic ß-cell functions. PLoS One 9:e99684 (2014). IHC ; Mouse . PubMed: 24915520
  • Sauter KA  et al. Pleiotropic effects of extended blockade of CSF1R signaling in adult mice. J Leukoc Biol 96:265-74 (2014). PubMed: 24652541
  • Knoch KP  et al. PTBP1 is required for glucose-stimulated cap-independent translation of insulin granule proteins and Coxsackieviruses in beta cells. Mol Metab 3:518-30 (2014). ICC/IF ; Mouse . PubMed: 25061557
  • Alkanani AK  et al. Kilham rat virus-induced type 1 diabetes involves beta cell infection and intra-islet JAK-STAT activation prior to insulitis. Virology 468-470C:19-27 (2014). Rat . PubMed: 25129435
  • Patel M  et al. Non-invasive bioluminescence imaging of ß-cell function in obese-hyperglycemic [ob/ob] mice. PLoS One 9:e106693 (2014). IHC-P ; Mouse . PubMed: 25198535
  • Téllez N & Montanya E Gastrin induces ductal cell dedifferentiation and ß-cell neogenesis after 90% pancreatectomy. J Endocrinol 223:67-78 (2014). PubMed: 25122000
  • Hasegawa Y  et al. Generation and characterization of Ins1-cre-driver C57BL/6N for exclusive pancreatic beta cell-specific Cre-loxP recombination. Exp Anim 63:183-91 (2014). PubMed: 24770644
  • Secher A  et al. The arcuate nucleus mediates GLP-1 receptor agonist liraglutide-dependent weight loss. J Clin Invest 124:4473-88 (2014). IHC ; Mouse . PubMed: 25202980
  • Liu X  et al. ß-Cell-Specific Glucocorticoid Reactivation Attenuates Inflammatory ß-Cell Destruction. Front Endocrinol (Lausanne) 5:165 (2014). IHC ; Mouse . PubMed: 25352830
  • Kuehn C  et al. Young porcine endocrine pancreatic islets cultured in fibrin and alginate gels show improved resistance towards human monocytes. Pathol Biol (Paris) 62:354-64 (2014). PubMed: 25239278
  • Nagasaki H  et al. Generation of insulin-producing cells from the mouse liver using ß cell-related gene transfer including Mafa and Mafb. PLoS One 9:e113022 (2014). IHC ; Mouse . PubMed: 25397325
  • Katsumata T  et al. Bioluminescence imaging of ß cells and intrahepatic insulin gene activity under normal and pathological conditions. PLoS One 8:e60411 (2013). IHC-P ; Mouse . PubMed: 23593212
  • Bramswig NC  et al. Epigenomic plasticity enables human pancreatic a to ß cell reprogramming. J Clin Invest 123:1275-84 (2013). IHC ; Human . PubMed: 23434589
  • Cedervall J  et al. HRG regulates tumor progression, epithelial to mesenchymal transition and metastasis via platelet-induced signaling in the pre-tumorigenic microenvironment. Angiogenesis 16:889-902 (2013). PubMed: 23793459
  • Gur C  et al. The expression of the beta cell-derived autoimmune ligand for the killer receptor nkp46 is attenuated in type 2 diabetes. PLoS One 8:e74033 (2013). Electron Microscopy ; Mouse, Gerbil . PubMed: 24009765
  • Suissa Y  et al. Gastrin: a distinct fate of neurogenin3 positive progenitor cells in the embryonic pancreas. PLoS One 8:e70397 (2013). ICC/IF ; Mouse . PubMed: 23940571
  • Liu Y  et al. Impaired autophagic function in rat islets with aging. Age (Dordr) 35:1531-44 (2013). IHC ; Rat . PubMed: 22843415
  • Schubert U  et al. Transplantation of pancreatic islets to adrenal gland is promoted by agonists of growth-hormone-releasing hormone. Proc Natl Acad Sci U S A 110:2288-93 (2013). IHC-Fr . PubMed: 23345449
  • Novikova L  et al. Variations in rodent models of type 1 diabetes: islet morphology. J Diabetes Res 2013:965832 (2013). IHC-P ; Human . PubMed: 23762878
  • Baragli L  et al. Obestatin Enhances In Vitro Generation of Pancreatic Islets through Regulation of Developmental Pathways. PLoS One 8:e64374 (2013). ICC/IF ; Mouse . PubMed: 23741322
  • Schwasinger-Schmidt T  et al. Long-term liraglutide treatment is associated with increased insulin content and secretion in ß-cells, and a loss of a-cells in ZDF rats. Pharmacol Res 76:58-66 (2013). IHC-P ; Rat . PubMed: 23891763
  • Wittig C  et al. Incorporation of bone marrow cells in pancreatic pseudoislets improves posttransplant vascularization and endocrine function. PLoS One 8:e69975 (2013). IHC-P . PubMed: 23875013
  • Wan X  et al. Recovery from overt type 1 diabetes ensues when immune tolerance and ß-cell formation are coupled with regeneration of endothelial cells in the pancreatic islets. Diabetes 62:2879-89 (2013). PubMed: 23715620
  • Fu X  et al. MicroRNA-26a targets ten eleven translocation enzymes and is regulated during pancreatic cell differentiation. Proc Natl Acad Sci U S A 110:17892-7 (2013). PubMed: 24114270
  • Hilderink J  et al. Label-Free Detection of Insulin and Glucagon within Human Islets of Langerhans Using Raman Spectroscopy. PLoS One 8:e78148 (2013). IHC-P ; Human . PubMed: 24167603
  • Crivello M  et al. Postnatal development of the endocrine pancreas in mice lacking functional GABAB receptors. Am J Physiol Endocrinol Metab 304:E1064-76 (2013). PubMed: 23531612
  • White MG  et al. Expression of mesenchymal and a-cell phenotypic markers in islet ß-cells in recently diagnosed diabetes. Diabetes Care 36:3818-20 (2013). ICC/IF ; Human . PubMed: 24062329
  • Kavishwar A & Moore A Sphingomyelin patches on pancreatic beta-cells are indicative of insulin secretory capacity. J Histochem Cytochem 61:910-9 (2013). Human . PubMed: 23920110
  • Dubiel EA  et al. In vitro morphogenesis of PANC-1 cells into islet-like aggregates using RGD-covered dextran derivative surfaces. Colloids Surf B Biointerfaces 89:117-25 (2012). IHC-P ; Human . PubMed: 21962947
  • Yebra M  et al. Endothelium-Derived Netrin-4 Supports Pancreatic Epithelial Cell Adhesion and Differentiation through Integrins a2ß1 and a3ß1. PLoS One 6:e22750 (2011). Flow Cyt ; Human . PubMed: 21829502
  • Huang HH  et al. Exercise increases insulin content and basal secretion in pancreatic islets in type 1 diabetic mice. Exp Diabetes Res 2011:481427 (2011). ICC/IF ; Mouse . PubMed: 21912535
  • Berchtold LA  et al. Huntingtin-interacting protein 14 is a type 1 diabetes candidate protein regulating insulin secretion and beta-cell apoptosis. Proc Natl Acad Sci U S A 108:E681-8 (2011). IHC-P ; Mouse . PubMed: 21705657
  • Himeno T  et al. Beneficial effects of exendin-4 on experimental polyneuropathy in diabetic mice. Diabetes 60:2397-406 (2011). PubMed: 21810596
  • Cole BK  et al. Valsartan protects pancreatic islets and adipose tissue from the inflammatory and metabolic consequences of a high-fat diet in mice. Hypertension 55:715-21 (2010). IHC-P ; Mouse . PubMed: 20100990
  • Colsoul B  et al. Loss of high-frequency glucose-induced Ca2+ oscillations in pancreatic islets correlates with impaired glucose tolerance in Trpm5-/- mice. Proc Natl Acad Sci U S A 107:5208-13 (2010). IHC-Fr ; Mouse . PubMed: 20194741
  • García-Tornadú I  et al. Disruption of the dopamine d2 receptor impairs insulin secretion and causes glucose intolerance. Endocrinology 151:1441-50 (2010). IHC-P ; Mouse . PubMed: 20147524
  • Nicholson JM  et al. Changes in islet microvasculature following streptozotocin-induced beta-cell loss and subsequent replacement in the neonatal rat. Exp Biol Med (Maywood) 235:189-98 (2010). PubMed: 20404034
  • Noda K  et al. An animal model of spontaneous metabolic syndrome: Nile grass rat. FASEB J 24:2443-53 (2010). IHC-FoFr ; Other . PubMed: 20335226
  • González-Pertusa JA  et al. Novel proapoptotic effect of hepatocyte growth factor: synergy with palmitate to cause pancreatic {beta}-cell apoptosis. Endocrinology 151:1487-98 (2010). ICC/IF ; Mouse . PubMed: 20176723
  • Cantley J  et al. Deletion of the von Hippel-Lindau gene in pancreatic beta cells impairs glucose homeostasis in mice. J Clin Invest 119:125-35 (2009). PubMed: 19065050
  • Bollyky PL  et al. The toll-like receptor signaling molecule Myd88 contributes to pancreatic beta-cell homeostasis in response to injury. PLoS One 4:e5063 (2009). IHC-Fr ; Mouse . PubMed: 19357791
  • Cheng J  et al. Immunity to islet grafts transduced with adenovirus vectors does not inhibit long-term islet function. Transpl Immunol 21:33-42 (2009). IHC-P ; Mouse . PubMed: 19224710
  • Gonzalez R  et al. Pancreatic beta cells colocalize insulin and pronesfatin immunoreactivity in rodents. Biochem Biophys Res Commun 381:643-8 (2009). ICC/IF ; Mouse . PubMed: 19248766
  • Chen YF  et al. Cisd2 deficiency drives premature aging and causes mitochondria-mediated defects in mice. Genes Dev 23:1183-94 (2009). IHC-P ; Mouse . PubMed: 19451219
  • Olofsson CS  et al. Impaired insulin exocytosis in neural cell adhesion molecule-/- mice due to defective reorganization of the submembrane F-actin network. Endocrinology 150:3067-75 (2009). PubMed: 19213846
  • Hayashi Y  et al. Mice deficient for glucagon gene-derived peptides display normoglycemia and hyperplasia of islet {alpha}-cells but not of intestinal L-cells. Mol Endocrinol 23:1990-9 (2009). IHC-FoFr ; Mouse . PubMed: 19819987
  • Gebe JA  et al. Autoreactive human T-cell receptor initiates insulitis and impaired glucose tolerance in HLA DR4 transgenic mice. J Autoimmun 30:197-206 (2008). IHC-Fr ; Mouse . PubMed: 17949947
  • Tian J  et al. Regulated insulin delivery from human epidermal cells reverses hyperglycemia. Mol Ther 16:1146-53 (2008). PubMed: 18431361
  • Kucia MJ  et al. Evidence that very small embryonic-like stem cells are mobilized into peripheral blood. Stem Cells 26:2083-92 (2008). ICC/IF ; Mouse . PubMed: 18511604
  • Habibi J  et al. Renin Inhibition Attenuates Insulin Resistance, Oxidative Stress, and Pancreatic Remodeling in the Transgenic Ren2 rat. Endocrinology : (2008). IHC-P ; Rat . PubMed: 18653711
  • Raffo A  et al. Role of vesicular monoamine transporter type 2 in rodent insulin secretion and glucose metabolism revealed by its specific antagonist tetrabenazine. J Endocrinol 198:41-9 (2008). PubMed: 18577569
  • Gustavsen CR  et al. An immunohistochemical study of the endocrine pancreas of the African ice rat, Otomys sloggetti robertsi. Acta Histochem 110:294-301 (2008). PubMed: 18406449
  • Mziaut H  et al. ICA512 signaling enhances pancreatic beta-cell proliferation by regulating cyclins D through STATs. Proc Natl Acad Sci U S A 105:674-9 (2008). IHC-P ; Mouse . PubMed: 18178618
  • Klinck R  et al. Specificity of four monoclonal anti-nkx6-1 antibodies. J Histochem Cytochem 56:415-24 (2008). IHC-Fr ; Human, Mouse . PubMed: 18212389
  • Starowicz KM  et al. Endocannabinoid Dysregulation in the Pancreas and Adipose Tissue of Mice Fed With a High-fat Diet. Obesity (Silver Spring) 16:553-565 (2008). IHC-P ; Mouse, Rat . PubMed: 18239598
  • Rittmeyer EN  et al. A dual role for IQGAP1 in regulating exocytosis. J Cell Sci 121:391-403 (2008). WB ; Mouse . PubMed: 18216334
  • Zhang Q  et al. R-type Ca(2+)-channel-evoked CICR regulates glucose-induced somatostatin secretion. Nat Cell Biol 9:453-60 (2007). ICC/IF ; Mouse . PubMed: 17369816
  • Zhu M  et al. Lymphotoxin receptor is required for the migration and selection of autoreactive T cells in thymic medulla. J Immunol 179:8069-75 (2007). ICC/IF ; Mouse . PubMed: 18056347
  • Sugiyama T  et al. Conserved markers of fetal pancreatic epithelium permit prospective isolation of islet progenitor cells by FACS. Proc Natl Acad Sci U S A 104:175-80 (2007). Mouse . PubMed: 17190805
  • Hermann M  et al. Dickkopf-3 is expressed in a subset of adult human pancreatic beta cells. Histochem Cell Biol 127:513-21 (2007). IHC-P ; Human . PubMed: 17347849
  • Knoch KP  et al. cAMP-dependent phosphorylation of PTB1 promotes the expression of insulin secretory granule proteins in beta cells. Cell Metab 3:123-34 (2006). PubMed: 16459313
  • Pedersen IL  et al. Generation and characterization of monoclonal antibodies against the transcription factor Nkx6.1. J Histochem Cytochem 54:567-74 (2006). PubMed: 16401696
  • Pedersen JK  et al. Endodermal expression of Nkx6 genes depends differentially on Pdx1. Dev Biol 288:487-501 (2005). PubMed: 16297379

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