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Rabbit monoclonal [EP327Y] to Insulin Receptor R
ab40782 recognises insulin receptor related receptor (IRR).
IHC-P more details Unsuitable for:
Flow Cyt or IP
Mouse, Rat, Human
Synthetic peptide corresponding to residues near the N-terminus of human IRR alpha subunit.
This product is a recombinant rabbit monoclonal antibody.
Produced using Abcam’s RabMAb
® technology. RabMAb ® technology is covered by the following U.S. Patents, No. 5,675,063 and/or 7,429,487.
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Tissue culture supernatant
Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/1000 - 1/2000. Predicted molecular weight: 80, 144 kDa.
1/50 - 1/100.
Is unsuitable for Flow Cyt or IP.
This receptor probably binds an insulin related protein and has a tyrosine-protein kinase activity. It phosphorylates the insulin receptor substrates IRS-1 and IRS-2.
Belongs to the protein kinase superfamily. Tyr protein kinase family. Insulin receptor subfamily.
Contains 3 fibronectin type-III domains. Contains 1 protein kinase domain.
Information by UniProt
Insulin receptor related receptor precursor antibody
Anti-Insulin Receptor R antibody [EP327Y] images
References for Anti-Insulin Receptor R antibody [EP327Y] (ab40782)
This product has been referenced in:
et al. LRP4 mutations alter Wnt/beta-catenin signaling and cause limb and kidney malformations in Cenani-Lenz syndrome. Am J Hum Genet 86:696-706 (2010).
Read more (PubMed: 20381006) »
See 1 Publication
for this product
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"