Overview

  • Product nameAnti-INT11 antibody
    See all INT11 primary antibodies
  • Description
    Rabbit polyclonal to INT11
  • Tested applicationsSuitable for: IHC-Pmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Horse, Chimpanzee, Rhesus monkey, Gorilla, Opossum, Orangutan, Elephant
  • Immunogen

    Synthetic peptide, corresponding to a region within the amino acids 550-600 of Human INT11, NP_060341.2

  • Positive control
    • Human breast carcinoma, prostate carcinoma.

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • Storage bufferPreservative: 0.09% Sodium Azide
    Constituents: 0.1% BSA, Tris buffered saline
  • Concentration information loading...
  • PurityImmunogen affinity purified
  • ClonalityPolyclonal
  • IsotypeIgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab84719 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P
  • Application notesIHC-P: 1/100 - 1/500. Epitope exposure is recommended. Epitope exposure with citrate buffer will enhance staining.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionCatalytic component of the Integrator complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes. Mediates the snRNAs 3' cleavage.
    • Sequence similaritiesBelongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. INTS11 subfamily.
    • DomainThe HXHXDH motif is essential for the endoribonuclease activity of the CPSF complex.
    • Cellular localizationNucleus. Cytoplasm.
    • Information by UniProt
    • Database links
    • Alternative names
      • 2410006F12Rik antibody
      • AU044035 antibody
      • Cleavage and polyadenylation specific factor 3 like antibody
      • Cleavage and polyadenylation-specific factor 3-like protein antibody
      • CPSF3 like protein antibody
      • CPSF3-like protein antibody
      • CPSF3L antibody
      • CPSF73L antibody
      • FLJ13294 antibody
      • FLJ20542 antibody
      • Human integrator complex subunit 11 antibody
      • INT 11 antibody
      • Int11 antibody
      • INT11_HUMAN antibody
      • Integrator complex subunit 11 antibody
      • INTS 11 antibody
      • INTS11 antibody
      • MGC124975 antibody
      • OTTHUMP00000044092 antibody
      • Protein related to CPSF subunits of 68 kDa antibody
      • RC 68 antibody
      • RC 68, related antibody
      • RC-68 antibody
      • RC68 antibody
      • Related to CPSF subunits 68 kDa antibody
      • Related to CPSF subunits, 68 kDa protein antibody
      • RGD1306841 antibody
      • RP23 242K15.19 antibody
      see all

    Anti-INT11 antibody images

    • Detection of Human INT11 by Immunohistochemistry.
      Sample: FFPE section of Human breast carcinoma.
      Antibody: ab84719 used at a dilution of 1/250.
      Detection: DAB staining.

    References for Anti-INT11 antibody (ab84719)

    ab84719 has not yet been referenced specifically in any publications.

    Product Wall

    There are currently no Abreviews or Questions for ab84719.
    Please use the links above to contact us or submit feedback about this product.

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"