Overview

  • Product name
    Anti-Integrin alpha 1 antibody [TS2/7] (FITC)
    See all Integrin alpha 1 primary antibodies
  • Description
    Mouse monoclonal [TS2/7] to Integrin alpha 1 (FITC)
  • Conjugation
    FITC. Ex: 493nm, Em: 528nm
  • Specificity
    This antibody recognises the human alpha 1 integrin subunit.
  • Tested applications
    Suitable for: Flow Cytmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    The details of the immunogen for this antibody are not available.

  • General notes

    Purified IgG conjugated to Fluorescein Isothiocyanate Isomer 1 (FITC).

Properties

Applications

Our Abpromise guarantee covers the use of ab34176 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
Flow Cyt
  • Application notes
    Flow Cyt: neat - 1/5. Use 10µl of the suggested working dilution to label 106 cells in 100µl.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • Function
      Integrin alpha-1/beta-1 is a receptor for laminin and collagen. It recognizes the proline-hydroxylated sequence G-F-P-G-E-R in collagen.
    • Sequence similarities
      Belongs to the integrin alpha chain family.
      Contains 7 FG-GAP repeats.
      Contains 1 VWFA domain.
    • Domain
      The integrin I-domain (insert) is a VWFA domain. Integrins with I-domains do not undergo protease cleavage.
    • Cellular localization
      Membrane.
    • Information by UniProt
    • Database links
    • Alternative names
      • CD 49a antibody
      • CD49 antigen-like family member A antibody
      • CD49a antibody
      • CD49a antigen antibody
      • Integrin alpha-1 antibody
      • ITA1_HUMAN antibody
      • Itga 1 antibody
      • ITGA1 antibody
      • Laminin and collagen receptor antibody
      • Very late activation protein 1 antibody
      • VLA 1 antibody
      • VLA-1 antibody
      • VLA1 antibody
      see all

    Images

    • Flow Cytometry analysis of HeLa cells labeling Integrin alpha 1 with ab34176.

    References

    This product has been referenced in:
    • Humtsoe JO  et al. A streptococcal collagen-like protein interacts with the alpha2beta1 integrin and induces intracellular signaling. J Biol Chem 280:13848-57 (2005). Read more (PubMed: 15647274) »

    See 1 Publication for this product

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    There are currently no Customer reviews or Questions for ab34176.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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