Anti-Integrin alpha 2 antibody [HMa2] (FITC) (ab95582)

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Overview

  • Product name
    Anti-Integrin alpha 2 antibody [HMa2] (FITC)
    See all Integrin alpha 2 primary antibodies
  • Description
    Armenian Hamster monoclonal [HMa2] to Integrin alpha 2 (FITC)
  • Conjugation
    FITC. Ex: 493nm, Em: 528nm
  • Tested applications
    Suitable for: Flow Cytmore details
  • Species reactivity
    Reacts with: Mouse
  • Immunogen

    Mouse colon carcinoma cell line Colon27.

  • Positive control
    • Mouse splenocytes.

Properties

Applications

Our Abpromise guarantee covers the use of ab95582 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
Flow Cyt Use 0.125µg for 105 cells. ab95582 can be used at 0.5 µg/per test. A test is defined as the amount (µg)/test of antibody that will stain a cell sample in a final volume of 100 µL. Cell number should be determined empirically but can range from 105 to 108 cells/test.



ab18473-Armenian Hamster monoclonal IgG, is suitable for use as an isotype control with this antibody.

Target

  • Function
    Integrin alpha-2/beta-1 is a receptor for laminin, collagen, collagen C-propeptides, fibronectin and E-cadherin. It recognizes the proline-hydroxylated sequence G-F-P-G-E-R in collagen. It is responsible for adhesion of platelets and other cells to collagens, modulation of collagen and collagenase gene expression, force generation and organization of newly synthesized extracellular matrix.
  • Sequence similarities
    Belongs to the integrin alpha chain family.
    Contains 7 FG-GAP repeats.
    Contains 1 VWFA domain.
  • Domain
    The integrin I-domain (insert) is a VWFA domain. Integrins with I-domains do not undergo protease cleavage.
  • Cellular localization
    Membrane.
  • Information by UniProt
  • Database links
    • Alternative names
      • BR antibody
      • CD 49b antibody
      • CD49 antigen like family member B antibody
      • CD49 antigen-like family member B antibody
      • CD49b antibody
      • CD49b antigen antibody
      • Collagen receptor antibody
      • DX5 antibody
      • Glycoprotein Ia deficiency included antibody
      • GP Ia antibody
      • GP Ia deficiency, included antibody
      • GPIa antibody
      • HPA 5 included antibody
      • HPA5 included antibody
      • Human platelet alloantigen system 5 antibody
      • Integrin alpha 2 antibody
      • Integrin alpha-2 antibody
      • Integrin, alpha 2 (CD49B alpha 2 subunit of VLA 2 receptor) antibody
      • ITA2_HUMAN antibody
      • ITGA2 antibody
      • Platelet alloantigen Br(a), included antibody
      • Platelet antigen Br antibody
      • Platelet glycoprotein GPIa antibody
      • Platelet glycoprotein Ia antibody
      • Platelet glycoprotein Ia/IIa antibody
      • Platelet membrane glycoprotein Ia antibody
      • Platelet receptor for collagen, deficiency of, included antibody
      • Very late activation protein 2 receptor alpha 2 subunit antibody
      • VLA 2 alpha chain antibody
      • VLA 2 antibody
      • VLA 2 subunit alpha antibody
      • VLA-2 subunit alpha antibody
      • VLA2 antibody
      • VLA2 receptor alpha 2 subunit antibody
      • VLAA2 antibody
      see all

    Anti-Integrin alpha 2 antibody [HMa2] (FITC) images

    • Flow Cytometry - Integrin alpha 2 antibody [HMa2] (FITC) (ab95582)
      Flow Cytometry - Integrin alpha 2 antibody [HMa2] (FITC) (ab95582)
      ab95582 used at 0.06µg staining Integrin alpha 2 in Mouse splenocytes by Flow Cytometry (shown in blue).

    References for Anti-Integrin alpha 2 antibody [HMa2] (FITC) (ab95582)

    ab95582 has not yet been referenced specifically in any publications.

    Publishing research using ab95582? Please let us know so that we can cite the reference in this datasheet.

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