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Products:Cardiovascular >> Blood >> Platelets

Anti-Integrin alpha 2b + beta 3 antibody [F11] (ab19775)

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Overview

Product name

Anti-Integrin alpha 2b + beta 3 antibody [F11]
See all Integrin alpha 2b + beta 3 products (7) ...

Description

Mouse monoclonal [F11] to Integrin alpha 2b + beta 3

Specificity

Recognises the common beta subunit of the integrin alpha 2b/beta 3 complex.

Tested applications

Flow Cytmore details

Cross reactivity

Reacts with

Human

Immunogen

Newborn rat bone cell suspensions.

Properties

Form

Liquid

Storage instructions

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze / thaw cycles.

Storage buffer

Preservative: 0.09% Sodium Azide
Constituents: 1% BSA, 0.01M PBS, 2mM EDTA. pH 7.2

Concentration

Concentration information loading...

Purity

Protein G purified

Clonality

Monoclonal

Clone number

F11

Isotype

IgG1

Research areas

Signal Transduction >> Cytoskeleton / ECM >> Cell Adhesion >> Integrins >> Beta
Signal Transduction >> Cytoskeleton / ECM >> Cell Adhesion >> Integrins >> Alpha
Immunology >> Cell Type Markers >> CD >> Platelets
Cardiovascular >> Blood >> Platelets

Applications

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Our Abpromise guarantee covers the use of ab19775 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Target

Relevance

The integrins are a family of more than 23 heterodimeric transmembrane proteins that mediate cell-cell adhesions as well as cell-substratum adhesions and signal transduction processes. Integrins are heterodimers consisting of noncovalently associated alpha and beta subunits. CD61 non-covalently associates with CD41 (alpha Ilb integrin) and is expressed by megakaryocytes and platelets. The CD61/CD41 complex acts as a receptor for such adhesive ligands as fibronectin, fibrinogen and von Willebrand factor during platelet stimulation.

Cellular localization

Cell Membrane

Alternative names

  • CD41 antibody
  • CD41b antibody
  • CD41b antibody
  • CD61 antibody
  • CD61 antibody
  • GP 2B antibody
  • GP 3A antibody
  • GP IIb antibody
  • GP IIIa antibody
  • GP3A antibody
  • GPIIIa antibody
  • GPIIIb antibody
  • GTA antibody
  • HPA3 antibody
  • Integrin alpha 2b antibody
  • Integrin alpha 2b antibody
  • Integrin beta 3 antibody
  • Integrin beta 3 antibody
  • ITGA2B antibody
  • ITGB3 antibody
  • Platelet glycoprotein IIb of IIb/IIIa complex antibody
see all

Database links

References for Anti-Integrin alpha 2b + beta 3 antibody [F11] (ab19775)

ab19775 has not yet been referenced specifically in any publications.

Publishing research using ab19775? Please let us know so that we can cite the reference in this datasheet

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"