Anti-Integrin alpha 4+beta 7 antibody [RM0059-2G18] (ab73261)

Overview

  • Product nameAnti-Integrin alpha 4+beta 7 antibody [RM0059-2G18]
    See all Integrin alpha 4+beta 7 primary antibodies
  • Description
    Rat monoclonal [RM0059-2G18] to Integrin alpha 4+beta 7
  • Tested applicationsSuitable for: IP, Flow Cyt, IHC-Pmore details
  • Species reactivity
    Reacts with: Mouse
  • Immunogen

    Cell lysates of mouse lymphocytes

Properties

Applications

Our Abpromise guarantee covers the use of ab73261 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IP 1/100 - 1/400.
Flow Cyt 1/50 - 1/200.
IHC-P 1/100 - 1/200.

Target

  • RelevanceIntegrin alpha 4 beta 7, also known as, the lymphocyte Peyer's patch adhesion molecule (LPAM1) is a member of the integrin family of cell surface receptors. It is expressed primarily on mucosal lymphocytes, but is also present on NK cells and eosinophils. The alpha 4 beta 7 heterodimer mediates the binding of lymphocytes to its ligand, mucosal vascular addressin (MAdCAM1) on the high endothelial venules, thereby directing the homing of lymphocytes into Peyer's patches and intestinal lamina propria.
  • Cellular localizationMembrane; Single pass type I membrane protein.
  • Database links
  • Alternative names
    • Antigen CD49D antibody
    • CD49d antibody
    • IA4 antibody
    • Integrin alpha 4 subunit antibody
    • Integrin alpha IV antibody
    • Integrin beta 7 antibody
    • Integrin beta 7 subunit antibody
    • ITGA4 antibody
    • ITGB7 antibody
    • LPAM1 antibody
    see all

Anti-Integrin alpha 4+beta 7 antibody [RM0059-2G18] images

  • ab73261 at 1/200 dilution, staining Integrin alpha 4+beta 7 in LPS exposed mouse spleen tissue section by Immunohistochemistry (Formalin/PFA fixed paraffin-embedded sections).

References for Anti-Integrin alpha 4+beta 7 antibody [RM0059-2G18] (ab73261)

ab73261 has not yet been referenced specifically in any publications.

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Thanks for your inquiry. We do not always have information on the most suitable antigen retrieval method for an antibody. I would recommended a heat induced epitope antigen retrieval method. I have attached the protocol for IHC-P. In i...

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