Anti-Integrin alpha 5 antibody [Hm alpha 5] (Phycoerythrin) (ab33674)

Overview

  • Product name
    Anti-Integrin alpha 5 antibody [Hm alpha 5] (Phycoerythrin)
    See all Integrin alpha 5 primary antibodies
  • Description
    Armenian Hamster monoclonal [Hm alpha 5] to Integrin alpha 5 (Phycoerythrin)
  • Conjugation
    Phycoerythrin. Ex: 488nm, Em: 575nm
  • Specificity
    ab33674 recognizes the mouse integrin alpha 5 subunit (CD49e).
  • Tested applications
    Suitable for: Flow Cytmore details
  • Species reactivity
    Reacts with: Mouse, Rat
  • Immunogen

    Purified mouse VLA-5 protein.

  • General notes

    Purified IgG conjugated to R. Phycoerythrin (RPE).

Properties

Applications

Our Abpromise guarantee covers the use of ab33674 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
Flow Cyt
  • Application notes
    Flow Cyt: 1/Neat - 1/10. Use 10µl of the suggested working dilution to label 106 cells in 100µl.
    Note: The Fc region of monoclonal antibodies may bind non-specifically to cells expressing low affinity fc receptors.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • Function
      Integrin alpha-5/beta-1 is a receptor for fibronectin and fibrinogen. It recognizes the sequence R-G-D in its ligands. In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions.
    • Sequence similarities
      Belongs to the integrin alpha chain family.
      Contains 7 FG-GAP repeats.
    • Cellular localization
      Membrane.
    • Information by UniProt
    • Database links
    • Alternative names
      • CD49 antigen-like family member E antibody
      • CD49e antibody
      • Fibronectin receptor subunit alpha antibody
      • Fibronectin receptor, alpha subunit antibody
      • FNRA antibody
      • Integrin alpha 5 (fibronectin receptor alpha) antibody
      • Integrin alpha-5 antibody
      • Integrin alpha-5 light chain antibody
      • Integrin alpha-F antibody
      • Integrin, alpha 5 (fibronectin receptor, alpha polypeptide) antibody
      • ITA5_HUMAN antibody
      • Itga5 antibody
      • Very late activation protein 5, alpha subunit antibody
      • VLA-5 antibody
      • VLA5 antibody
      • VLA5A antibody
      see all

    Images

    References

    ab33674 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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