For the best experience on the Abcam website please upgrade to a modern browser such as
Storage instructions Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C.
Storage buffer PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Purity Tissue culture supernatant
Clone number EPR4166
Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/1000 - 1/10000. Detects a band of approximately 150 kDa (predicted molecular weight: 130 kDa).
Application notes Is unsuitable for Flow Cyt,ICC,IHC-P or IP.
Function Integrin alpha-E/beta-7 is a receptor for E-cadherin. It mediates adhesion of intra-epithelial T-lymphocytes to epithelial cell monolayers.
Tissue specificity Expressed on a subclass of T-lymphocytes known as intra-epithelial lymphocytes which are located between mucosal epithelial cells.
Sequence similarities Belongs to the integrin alpha chain family. Contains 7 FG-GAP repeats. Contains 1 VWFA domain.
Domain The integrin I-domain (insert) is a VWFA domain. Integrins with I-domains do not undergo protease cleavage.
Cellular localization Membrane.
Information by UniProt
Anti-Integrin alpha E antibody [EPR4166] images
Western blot - Integrin alpha E antibody [EPR4166] (ab108503)
All lanes : Anti-Integrin alpha E antibody [EPR4166] (ab108503) at 1/1000 dilution Lane 1 : HuT-78 cell lysate Lane 2 : Jurkat cell lysate Lane 3 : A431 cell lysate Lane 4 : HeLa cell lysate Lane 5 : K562 cell lysate Lysates/proteins at 10 µg per lane. Predicted band size : 130 kDa Observed band size : 150 kDa ( why is the actual band size different from the predicted?)
References for Anti-Integrin alpha E antibody [EPR4166] (ab108503)
This product has been referenced in:
et al. Multiple lesions of gastrointestinal tract invasion by monomorphic epitheliotropic intestinal T-cell lymphoma, accompanied by duodenal and intestinal enteropathy-like lesions and microscopic lymphocytic proctocolitis: a case series. Diagn Pathol 11:66 (2016).
Read more (PubMed: 27457239) »
See 1 Publication
for this product
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"