Overview

  • Product nameAnti-Integrin alpha V antibody
    See all Integrin alpha V primary antibodies
  • Description
    Rabbit polyclonal to Integrin alpha V
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Sheep, Cow, Pig
  • Immunogen

    Synthetic peptide conjugated to KLH derived from within residues 1 - 100 of Human Integrin alpha V.

    (Peptide available as ab94839.)

  • Positive control
    • This antibody gave a positive signal in HUVEC whole cell lysate.

Properties

Associated products

Applications

Our Abpromise guarantee covers the use of ab94704 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB
  • Application notesWB: Use at a concentration of 1 µg/ml. Detects a band of approximately 130 & 148 kDa (predicted molecular weight: 116 kDa).
    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionThe alpha-V integrins are receptors for vitronectin, cytotactin, fibronectin, fibrinogen, laminin, matrix metalloproteinase-2, osteopontin, osteomodulin, prothrombin, thrombospondin and vWF. They recognize the sequence R-G-D in a wide array of ligands. In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions.
    • Sequence similaritiesBelongs to the integrin alpha chain family.
      Contains 7 FG-GAP repeats.
    • Cellular localizationMembrane.
    • Information by UniProt
    • Database links
    • Alternative names
      • antigen identified by monoclonal antibody L230 antibody
      • CD 51 antibody
      • CD51 antibody
      • DKFZp686A08142 antibody
      • integrin alpha V beta 3 antibody
      • integrin alpha-V antibody
      • Integrin alpha-V light chain antibody
      • integrin alphaVbeta3 antibody
      • integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51) antibody
      • ITAV_HUMAN antibody
      • ITGAV antibody
      • MSK 8 antibody
      • Msk8 antibody
      • Vitronectin receptor subunit alpha antibody
      • VNRA antibody
      • VTNR antibody
      see all

    Anti-Integrin alpha V antibody images

    • Anti-Integrin alpha V antibody (ab94704) at 1 µg/ml + HUVEC (Human Umbilical Vein Endothelial Cell) Whole Cell Lysate at 10 µg

      Secondary
      Goat polyclonal to Rabbit IgG - H&L - Pre-Adsorbed (HRP) at 1/3000 dilution
      Developed using the ECL technique

      Performed under reducing conditions.

      Predicted band size : 116 kDa
      Observed band size : 130 + 148 kDa (why is the actual band size different from the predicted?)
      Additional bands at : 25 kDa,58 kDa,62 kDa. We are unsure as to the identity of these extra bands.

      Exposure time : 10 minutes

    References for Anti-Integrin alpha V antibody (ab94704)

    ab94704 has not yet been referenced specifically in any publications.

    Product Wall

    There are currently no Abreviews or Questions for ab94704.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"