The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application notesFlow Cyt: Use 1µg for 105-8 cells in 100µl.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
FunctionThe alpha-V integrins are receptors for vitronectin, cytotactin, fibronectin, fibrinogen, laminin, matrix metalloproteinase-2, osteopontin, osteomodulin, prothrombin, thrombospondin and vWF. They recognize the sequence R-G-D in a wide array of ligands. In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions.
Sequence similaritiesBelongs to the integrin alpha chain family. Contains 7 FG-GAP repeats.
antigen identified by monoclonal antibody L230 antibody
CD 51 antibody
integrin alpha V beta 3 antibody
integrin alpha-V antibody
Integrin alpha-V light chain antibody
integrin alphaVbeta3 antibody
integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51) antibody
MSK 8 antibody
Vitronectin receptor subunit alpha antibody
Anti-Integrin alpha V antibody [RMV-7] (Biotin) images
Flow Cytometry - Integrin alpha V antibody [RMV-7] (Biotin) (ab93580)
Staining of C57Bl/6 bone marrow cells with 0.5 µg of Biotin Rat IgG1 Isotype Control (open histogram) and 0.5 µg ab93580 (colored histogram) followed by SAv-PE. Cells in the large scatter population were used for analysis.
References for Anti-Integrin alpha V antibody [RMV-7] (Biotin) (ab93580)
has not yet been referenced specifically in any publications.
Publishing research using ab93580? Please let us know so that we can cite the reference in this datasheet.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"