Validated using a knockout cell line

Anti-Integrin beta 1 antibody [EP1041Y] (ab52971)

Publishing research using ab52971? Please let us know so that we can cite the reference in this datasheet.

ab52971 has been referenced in 54 publications.

  • Fang T  et al. Tumor-derived exosomal miR-1247-3p induces cancer-associated fibroblast activation to foster lung metastasis of liver cancer. Nat Commun 9:191 (2018). PubMed: 29335551
  • Zeng B  et al. SPP1 promotes ovarian cancer progression via Integrin ß1/FAK/AKT signaling pathway. Onco Targets Ther 11:1333-1343 (2018). PubMed: 29559792
  • Wang X  et al. Biocompatibility of biological material polylactic acid with stem cells from human exfoliated deciduous teeth. Biomed Rep 6:519-524 (2017). PubMed: 28515910
  • Paetau S  et al. Neuronal ICAM-5 Inhibits Microglia Adhesion and Phagocytosis and Promotes an Anti-inflammatory Response in LPS Stimulated Microglia. Front Mol Neurosci 10:431 (2017). PubMed: 29311819
  • Lv C  et al. MiR-31 promotes mammary stem cell expansion and breast tumorigenesis by suppressing Wnt signaling antagonists. Nat Commun 8:1036 (2017). PubMed: 29051494
  • Georgiadou M  et al. AMPK negatively regulates tensin-dependent integrin activity. J Cell Biol 216:1107-1121 (2017). PubMed: 28289092
  • Andrlová H  et al. Biglycan expression in the melanoma microenvironment promotes invasiveness via increased tissue stiffness inducing integrin-ß1 expression. Oncotarget 8:42901-42916 (2017). PubMed: 28476030
  • Aleckovic M  et al. Identification of Nidogen 1 as a lung metastasis protein through secretome analysis. Genes Dev 31:1439-1455 (2017). PubMed: 28827399
  • Chang TY  et al. Paxillin facilitates timely neurite initiation on soft-substrate environments by interacting with the endocytic machinery. Elife 6:N/A (2017). PubMed: 29271742
  • Grassmé H  et al. ß1-Integrin Accumulates in Cystic Fibrosis Luminal Airway Epithelial Membranes and Decreases Sphingosine, Promoting Bacterial Infections. Cell Host Microbe 21:707-718.e8 (2017). IHC-P, ICC/IF ; Human . PubMed: 28552668
  • Hatanaka K  et al. Molecular mechanisms of the angiogenic effects of low-energy shock wave therapy: roles of mechanotransduction. Am J Physiol Cell Physiol 311:C378-85 (2016). PubMed: 27413171
  • Zhao W  et al. Effect of TGF-ß1 on the Migration and Recruitment of Mesenchymal Stem Cells after Vascular Balloon Injury: Involvement of Matrix Metalloproteinase-14. Sci Rep 6:21176 (2016). IHC-P ; Rat . PubMed: 26880204
  • Lindsay LA  et al. Uterine focal adhesions are retained at implantation after rat ovarian hyperstimulation. Reproduction 152:753-763 (2016). PubMed: 27651522
  • Chen G  et al. Integrins ß1 and ß3 are biomarkers of uterine condition for embryo transfer. J Transl Med 14:303 (2016). PubMed: 27782833
  • Wang X  et al. Knockdown of HMGN2 increases the internalization of Klebsiella pneumoniae by respiratory epithelial cells through the regulation of a5ß1 integrin expression. Int J Mol Med 38:737-46 (2016). Human . PubMed: 27460641
  • Liu H  et al. Aspergillus fumigatus CalA binds to integrin a5ß1 and mediates host cell invasion. Nat Microbiol 2:16211 (2016). PubMed: 27841851
  • Masuda Y  et al. TRIM29 regulates the p63-mediated pathway in cervical cancer cells. Biochim Biophys Acta 1853:2296-305 (2015). PubMed: 26071105
  • Szeto HH  et al. Improving mitochondrial bioenergetics under ischemic conditions increases warm ischemia tolerance in the kidney. Am J Physiol Renal Physiol 308:F11-21 (2015). PubMed: 25339695
  • Okolicsanyi RK  et al. Human Mesenchymal Stem Cells Retain Multilineage Differentiation Capacity Including Neural Marker Expression after Extended In Vitro Expansion. PLoS One 10:e0137255 (2015). PubMed: 26356539
  • Inaba J  et al. Lunasin sensitivity in non-small cell lung cancer cells is linked to suppression of integrin signaling and changes in histone acetylation. Int J Mol Sci 15:23705-24 (2014). WB ; Human . PubMed: 25530619
  • Bayer ML  et al. Release of tensile strain on engineered human tendon tissue disturbs cell adhesions, changes matrix architecture, and induces an inflammatory phenotype. PLoS One 9:e86078 (2014). WB ; Human . PubMed: 24465881
  • Mai A  et al. Distinct c-Met activation mechanisms induce cell rounding or invasion through pathways involving integrins, RhoA and HIP1. J Cell Sci 127:1938-52 (2014). PubMed: 24790222
  • Ray S  et al. LIM kinase regulation of cytoskeletal dynamics is required for salivary gland branching morphogenesis. Mol Biol Cell 25:2393-407 (2014). PubMed: 24966172
  • Lee K  et al. Inactivation of Integrin-ß1 Prevents the Development of Polycystic Kidney Disease after the Loss of Polycystin-1. J Am Soc Nephrol N/A:N/A (2014). PubMed: 25145933
  • Sen N  et al. Very late antigen-5 facilitates stromal progenitor cell differentiation into myofibroblast. Stem Cells Transl Med 3:1342-53 (2014). PubMed: 25273539
  • Ribeiro-Resende VT  et al. Mice lacking GD3 synthase display morphological abnormalities in the sciatic nerve and neuronal disturbances during peripheral nerve regeneration. PLoS One 9:e108919 (2014). IF ; Mouse . PubMed: 25330147
  • McGough IJ  et al. Identification of molecular heterogeneity in SNX27-retromer-mediated endosome-to-plasma-membrane recycling. J Cell Sci 127:4940-53 (2014). PubMed: 25278552
  • Wang JY  et al. Involvement of IRS-1 interaction with ADAM10 in the regulation of neurite extension. J Cell Physiol 229:1039-46 (2014). PubMed: 24648009
  • Sheyn D  et al. PTH promotes allograft integration in a calvarial bone defect. Mol Pharm 10:4462-71 (2013). PubMed: 24131143
  • Batlle R  et al. Snail1 controls TGF-ß responsiveness and differentiation of mesenchymal stem cells. Oncogene 32:3381-9 (2013). WB ; Mouse . PubMed: 22869142
  • Xiang Y  et al. Regulation of protein glycosylation and sorting by the Golgi matrix proteins GRASP55/65. Nat Commun 4:1659 (2013). PubMed: 23552074
  • Carbonell WS  et al. ß1 integrin targeting potentiates antiangiogenic therapy and inhibits the growth of bevacizumab-resistant glioblastoma. Cancer Res 73:3145-54 (2013). IHC-P ; Human . PubMed: 23644530
  • Sosa LJ  et al. Amyloid precursor protein is an autonomous growth cone adhesion molecule engaged in contact guidance. PLoS One 8:e64521 (2013). PubMed: 23691241
  • Steinberg F  et al. A global analysis of SNX27-retromer assembly and cargo specificity reveals a function in glucose and metal ion transport. Nat Cell Biol 15:461-71 (2013). PubMed: 23563491
  • Wang YC  et al. Protogenin prevents premature apoptosis of rostral cephalic neural crest cells by activating the a5ß1-integrin. Cell Death Dis 4:e651 (2013). PubMed: 23744351
  • Faulk DM  et al. The effect of detergents on the basement membrane complex of a biologic scaffold material. Acta Biomater N/A:N/A (2013). PubMed: 24055455
  • Chang W  et al. Gene expression profiling-derived immunohistochemistry signature with high prognostic value in colorectal carcinoma. Gut N/A:N/A (2013). WB, IHC ; Human . PubMed: 24173294
  • Hinwood M  et al. Chronic stress induced remodeling of the prefrontal cortex: structural re-organization of microglia and the inhibitory effect of minocycline. Cereb Cortex 23:1784-97 (2013). PubMed: 22710611
  • Ophir MJ  et al. The N terminus of SKAP55 enables T cell adhesion to TCR and integrin ligands via distinct mechanisms. J Cell Biol 203:1021-41 (2013). PubMed: 24368808
  • Gandavarapu NR  et al. Extracellular matrix protein adsorption to phosphate-functionalized gels from serum promotes osteogenic differentiation of human mesenchymal stem cells. Acta Biomater 9:4525-34 (2013). Human . PubMed: 22982322
  • Henderson NC  et al. Targeting of av integrin identifies a core molecular pathway that regulates fibrosis in several organs. Nat Med 19:1617-24 (2013). WB ; Mouse . PubMed: 24216753
  • Allaire PD  et al. Interplay between Rab35 and Arf6 controls cargo recycling to coordinate cell adhesion and migration. J Cell Sci 126:722-31 (2013). PubMed: 23264734
  • Tomkiewicz C  et al. The aryl hydrocarbon receptor regulates focal adhesion sites through a non-genomic FAK/Src pathway. Oncogene : (2012). PubMed: 22665056
  • Plodinec M  et al. The nanomechanical signature of breast cancer. Nat Nanotechnol 7:757-65 (2012). PubMed: 23085644
  • Sachar A  et al. Osteoblasts responses to three-dimensional nanofibrous gelatin scaffolds. J Biomed Mater Res A 100:3029-41 (2012). PubMed: 22707234
  • Pan X  et al. Activation of focal adhesion kinase enhances the adhesion of Fusarium solani to human corneal epithelial cells via the tyrosine-specific protein kinase signaling pathway. Mol Vis 17:638-46 (2011). WB ; Human . PubMed: 21403855
  • Mantoni TS  et al. Pancreatic Stellate Cells Radioprotect Pancreatic Cancer Cells through {beta}1-Integrin Signaling. Cancer Res 71:3453-8 (2011). WB ; Human . PubMed: 21558392
  • Szeto HH  et al. Mitochondria-targeted peptide accelerates ATP recovery and reduces ischemic kidney injury. J Am Soc Nephrol 22:1041-52 (2011). PubMed: 21546574
  • Cosset EC  et al. Involvement of the TGFß pathway in the regulation of a(5) ß(1) integrins by caveolin-1 in human glioblastoma. Int J Cancer : (2011). PubMed: 21901744
  • Tharmalingam S  et al. Calcium-sensing Receptor Modulates Cell Adhesion and Migration via Integrins. J Biol Chem 286:40922-33 (2011). ICC/IF ; Rat . PubMed: 21969374
  • Guo F  et al. Gingival fibroblasts display reduced adhesion and spreading on extracellular matrix: a possible basis for scarless tissue repair? PLoS One 6:e27097 (2011). WB ; Human . PubMed: 22073262
  • Chen TT  et al. Anchorage of VEGF to the extracellular matrix conveys differential signaling responses to endothelial cells. J Cell Biol 188:595-609 (2010). PubMed: 20176926
  • Kadota Y  et al. Mesenchymal stem cells support hepatocyte function in engineered liver grafts. Organogenesis 10:268-77 (0). PubMed: 24488046
  • Barakat SM & Siar CH Differential expression of stem cell-like proteins in normal, hyperplastic and dysplastic oral epithelium. J Appl Oral Sci 23:79-86 (0). IHC . PubMed: 25760270


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