Overview

  • Product name
    Anti-Interleukin 34 antibody
    See all Interleukin 34 primary antibodies
  • Description
    Rabbit polyclonal to Interleukin 34
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Mouse, Rat, Human
  • Immunogen

    A 16 amino acid synthetic peptide from near the N terminus of human Interleukin 34. (ACD13474).

  • Positive control
    • Human brain tissue lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab74548 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 0.25 - 0.5 µg/ml. Detects a band of approximately 45 kDa (predicted molecular weight: 27 kDa).

Target

  • Function
    Cytokine that promotes the differentiation and viability of monocytes and macrophages. Stimulates phosphorylation of MAPK1/ERK2 AND MAPK3/ERK1. Ligand for colony-stimulating factor-1 receptor CSF1R.
  • Tissue specificity
    Detected in the sinusoidal epithelium in the red pulp of spleen (at protein level). Predominantly expressed in spleen. Also detected in a range of other tissues including heart, brain, lung, liver, kidney, thymus, testis, ovary, small intestine, prostate and colon.
  • Sequence similarities
    Belongs to the IL-34 family.
  • Cellular localization
    Secreted.
  • Information by UniProt
  • Database links
  • Alternative names
    • C16orf77 antibody
    • Chromosome 16 open reading frame 77 antibody
    • FPT025 antibody
    • IL 34 antibody
    • IL-34 antibody
    • Il34 antibody
    • IL34_HUMAN antibody
    • Interleukin 34 antibody
    • Interleukin-34 antibody
    • Interleukin34 antibody
    • MGC34647 antibody
    see all

Images

  • Anti-Interleukin 34 antibody (ab74548) at 1 µg/ml + Recombinant human IL-34 protein at 0.001 µg

    Predicted band size : 27 kDa
    Observed band size : 45 kDa (why is the actual band size different from the predicted?)
  • All lanes : Anti-Interleukin 34 antibody (ab74548) at 0.25 µg/ml

    Lane 1 : Human brain tissue lysate, minus immunising peptide
    Lane 2 : Human brain tissue lysate, plus immmunising peptide

    Lysates/proteins at 15 µg per lane.


    Predicted band size : 27 kDa
    Observed band size : 45 kDa (why is the actual band size different from the predicted?)

References

ab74548 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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