Anti-Ionotropic glutamate receptor 2 + 3 antibody (ab27225)

Overview

  • Product nameAnti-Ionotropic glutamate receptor 2 + 3 antibody
    See all Ionotropic glutamate receptor 2 + 3 primary antibodies
  • Description
    Rabbit polyclonal to Ionotropic glutamate receptor 2 + 3
  • Tested applicationsSuitable for: IHC-FoFr, WB, IP, IHC-Pmore details
  • Species reactivity
    Reacts with: Pigeon, Human
    Predicted to work with: Mouse, Rat, Bird, Monkey
  • Immunogen

    A synthetic peptide from C terminus of Human GluR2/3.

  • Positive control
    • Cerebellum

Properties

Applications

Our Abpromise guarantee covers the use of ab27225 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-FoFr Use at an assay dependent concentration. PubMed: 20674673
WB Use at an assay dependent concentration. Predicted molecular weight: 96 kDa.
IP Use at an assay dependent concentration.
IHC-P 1/50. Perform heat mediated antigen retrieval before commencing with IHC staining protocol.

Target

  • RelevanceIon channels activated by glutamate are typically divided into two classes. Those sensitive to N-methyl-D-aspartate (NMDA) are designated NMDA receptors (NMDAR) while those activated by a-amino-3-hydroxy-5-methyl-4-isoxalone propionic acid (AMPA) are known as AMPA receptors (AMPAR). AMPAR are comprised of four distinct Glutamate Receptor Subunits (GluR1-4) and they play key roles in almost all excitatory neurotransmission in the brain. The GluR2 subunit is widely expressed throughout the nervous system where it is thought to play key roles in synaptic plasticity and learning and memory.
  • Cellular localizationCell Membrane; multi-pass membrane protein.
  • Database links
  • Alternative names
    • AMPA selective glutamate receptor 2 antibody
    • AMPA selective glutamate receptor 3 antibody
    • GluR K2 antibody
    • GluR K3 antibody
    • GLURB antibody
    • GLURC antibody
    • GLUTAMATE RECEPTOR 2 antibody
    • GLUTAMATE RECEPTOR 3 antibody
    • Glutamate receptor ionotropic AMPA 2 antibody
    • Glutamate receptor ionotropic AMPA 3 antibody
    • GRIA2 antibody
    • GRIA3 antibody
    see all

Anti-Ionotropic glutamate receptor 2 + 3 antibody images

  • Ab27225 at a dilution of 1/50, staining ionotropic Glutamate Receptor 2+3 in Human cerebellum by Immunohistochemistry (formalin fixed, paraffin embedded sections).

References for Anti-Ionotropic glutamate receptor 2 + 3 antibody (ab27225)

This product has been referenced in:
  • Ripka S  et al. Glutamate receptor GRIA3--target of CUX1 and mediator of tumor progression in pancreatic cancer. Neoplasia 12:659-67 (2010). IHC-P ; Human . Read more (PubMed: 20689760) »
  • Cabral AL  et al. GluR2/3 label expression of the AMPA-type glutamate receptor in the hippocampal formation of the homing pigeon stabilizes just after birth. Neurosci Lett 483:73-7 (2010). WB, IHC-FoFr ; Pigeon . Read more (PubMed: 20674673) »

See all 2 Publications for this product

Product Wall

There are currently no Abreviews or Questions for ab27225.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"