Overview

  • Product name
  • Description
    Goat polyclonal to IP3KC
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide:

    ETERPKQKTEPDRSS

    , corresponding to internal sequence amino acids 105-119 of Human IP3KC (NP_079470.1)

  • Positive control
    • Human Pancreas lysate

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
  • Storage buffer
    Preservative: 0.02% Sodium Azide
    Constituents: 0.5% BSA, Tris buffered saline, pH 7.3
  • Concentration information loading...
  • Purity
    Immunogen affinity purified
  • Purification notes
    Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab92283 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB
  • Application notes
    WB: Use at a concentration of 1 - 3 µg/ml. Predicted molecular weight: 75 kDa.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • Function
      Can phosphorylate inositol 2,4,5-triphosphate to inositol 2,4,5,6-tetraphosphate.
    • Tissue specificity
      Highly expressed in pancreas, skeletal muscle, liver, placenta and weakly in kidney and brain.
    • Involvement in disease
      Defects in ITPKC are a cause of Kawasaki disease (KWD) [MIM:611775]; also known as mucocutaneous lymph node syndrome or infantile polyarteritis. Kawasaki disease is an acute, self-limited vasculitis of infants and children characterized by prolonged fever unresponsive to antibiotics, polymorphous skin rash, erythema of the oral mucosa, lips, and tongue, erythema of the palms and soles, bilateral conjunctival injection, and cervical lymphadenopathy. Coronary artery aneurysms develop in 15 to 25% of those left untreated, making Kawasaki disease the leading cause of acquired heart disease among children in developed countries.
    • Sequence similarities
      Belongs to the inositol phosphokinase (IPK) family.
    • Cellular localization
      Nucleus. Cytoplasm. Shuttles actively between nucleus and cytoplasm with both nuclear import and nuclear export activity.
    • Information by UniProt
    • Database links
    • Alternative names
      • 4 antibody
      • 5-trisphosphate 3-kinase C antibody
      • Inositol 1 antibody
      • inositol 1,4,5 trisphosphate 3 kinase C antibody
      • Inositol trisphosphate 3 kinase C antibody
      • Inositol-trisphosphate 3-kinase C antibody
      • InsP 3 kinase C antibody
      • InsP 3-kinase C antibody
      • IP3 3-kinase C antibody
      • IP3 3KC antibody
      • IP3K C antibody
      • IP3KC antibody
      • IP3KC_HUMAN antibody
      • Itpkc antibody
      see all

    Anti-IP3KC antibody images

    • Anti-IP3KC antibody (ab92283) at 1 µg/ml + Human Pancreas lysate at 35 µg
      Developed using the ECL technique

      Predicted band size : 75 kDa
      Observed band size : 75 kDa

    References for Anti-IP3KC antibody (ab92283)

    ab92283 has not yet been referenced specifically in any publications.

    Product Wall

    There are currently no Abreviews or Questions for ab92283.
    Please use the links above to contact us or submit feedback about this product.

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

    Sign up