Overview

  • Product nameAnti-IpaD antibody [7]
  • Description
    Mouse monoclonal [7] to IpaD
  • Tested applicationsSuitable for: ELISAmore details
  • Species reactivity
    Reacts with: Recombinant Fragment
  • Immunogen

    Recombinant fragment, corresponding to amino acids 11-189 of Shigella dysenteriae IpaD (YP_406165.1)

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term.
  • Storage bufferPreservative: 0.02% Proclin
    Constituents: Tris HCl, Sodium citrate, pH 7.0
  • Concentration information loading...
  • PurityProtein G purified
  • ClonalityMonoclonal
  • Clone number7
  • IsotypeIgG1
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab101123 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA Use at an assay dependent dilution.

Target

  • RelevanceRequired for bacterial invasion of host cells. Controls ipaB and ipaC secretion, and the efficiency with which they are physically inserted into target cell membranes. These proteins are exported via TTSS to form a pore in the host membrane that allows the translocation of the other effectors into the host cytoplasm. Along with ipaB, is essential for both blocking secretion through the Mxi/Spa translocon in the absence of a secretion-inducing signal, and for controlling the level of secretion in the presence of this signal.
  • Cellular localizationSecreted
  • Alternative names
    • Invasin ipaD antibody
    • secreted by the Mxi-Spa machinery, required for entry of bacteria into epithelial cells antibody

References for Anti-IpaD antibody [7] (ab101123)

ab101123 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab101123.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"