Overview

  • Product nameAnti-IPO11 antibody - N-terminal
    See all IPO11 primary antibodies
  • Description
    Rabbit polyclonal to IPO11 - N-terminal
  • Tested applicationsSuitable for: WB, ELISAmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide selected from the N terminal region of Human IPO11 conjugated to KLH (NP_057422.3).

  • Positive control
    • Hela cell line lysates

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • Storage bufferPreservative: 0.09% Sodium Azide
    Constituents: PBS
  • Concentration information loading...
  • PurityImmunogen affinity purified
  • Purification notesab93475 is purified through a protein A column, followed by peptide affinity purification.
  • ClonalityPolyclonal
  • IsotypeIgG
  • Research areas

Associated products

Applications

Our Abpromise guarantee covers the use of ab93475 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB
ELISA
  • Application notesELISA: 1/1000.
    WB: 1/100 - 1/500. Predicted molecular weight: 113 kDa.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionFunctions in nuclear protein import as nuclear transport receptor. Serves as receptor for nuclear localization signals (NLS) in cargo substrates. Is thought to mediate docking of the importin/substrate complex to the nuclear pore complex (NPC) through binding to nucleoporin and the complex is subsequently translocated through the pore by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to the importin, the importin/substrate complex dissociates and importin is re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran. The directionality of nuclear import is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus (By similarity). Mediates the nuclear import of UBE2E3, and of RPL12.
    • Sequence similaritiesBelongs to the importin beta family.
      Contains 15 HEAT repeats.
      Contains 1 importin N-terminal domain.
    • Cellular localizationCytoplasm. Nucleus.
    • Information by UniProt
    • Database links
    • Alternative names
      • Imp11 antibody
      • Importin 11 antibody
      • Importin-11 antibody
      • IPO11 antibody
      • IPO11_HUMAN antibody
      • Ran binding protein 11 antibody
      • Ran-binding protein 11 antibody
      • RanBP11 antibody
      • SLRN antibody
      • Synleurin antibody
      see all

    Anti-IPO11 antibody - N-terminal images

    • Anti-IPO11 antibody - N-terminal (ab93475) at 1/100 dilution + HeLa cell line lysates at 35 µg

      Predicted band size : 113 kDa

    References for Anti-IPO11 antibody - N-terminal (ab93475)

    ab93475 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"