Overview

  • Product nameAnti-IRAKM antibody
    See all IRAKM primary antibodies
  • Description
    Mouse monoclonal to IRAKM
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant fragment: RIDRMTQKTP FECSQSEVMF LSLDKKPESK RNEEACNMPS SSCEESWFPK YIVPSQDLRP YKVNIDPSSE APGHSCRSRP VESSCSSKFS WDEYEQYKKE , corresponding to amino acids 497-596 of Human IRAKM

Properties

Applications

Our Abpromise guarantee covers the use of ab56884 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB
  • Application notesWB: Use at a concentration of 1-5 µg/ml.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionInhibits dissociation of IRAK1 and IRAK4 from the Toll-like receptor signaling complex by either inhibiting the phosphorylation of IRAK1 and IRAK4 or stabilizing the receptor complex.
    • Tissue specificityExpressed predominantly in peripheral blood lymphocytes.
    • Involvement in diseaseDefects in IRAK3 are associated with susceptibility to asthma-related traits type 5 (ASRT5) [MIM:611064]. Asthma-related traits include clinical symptoms of asthma, such as coughing, wheezing, dyspnea, bronchial hyperresponsiveness as assessed by methacholine challenge test, serum IgE levels, atopy, and atopic dermatitis.
    • Sequence similaritiesBelongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. Pelle subfamily.
      Contains 1 death domain.
      Contains 1 protein kinase domain.
    • Information by UniProt
    • Database links
    • Alternative names
      • ASRT5 antibody
      • IL 1 receptor associated kinase M antibody
      • IL-1 receptor-associated kinase M antibody
      • IL1 receptor associated kinase M antibody
      • Interleukin 1 receptor associated kinase 3 antibody
      • Interleukin 1 receptor associated kinase M antibody
      • Interleukin-1 receptor-associated kinase 3 antibody
      • IRAK M antibody
      • IRAK-3 antibody
      • IRAK-M antibody
      • Irak3 antibody
      • IRAK3_HUMAN antibody
      see all

    Anti-IRAKM antibody images



    • Predicted band size : 68 kDa
      IRAKM antibody (ab56884) at 1ug/lane + HeLa cell lysate at 25ug/lane.

    References for Anti-IRAKM antibody (ab56884)

    ab56884 has not yet been referenced specifically in any publications.

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