Anti-IRE1 (phospho S724) antibody [EPR5253] (ab124945)

Publishing research using ab124945? Please let us know so that we can cite the reference in this datasheet.

ab124945 has been referenced in 17 publications.

  • Anderson GR  et al. Dysregulation of mitochondrial dynamics proteins are a targetable feature of human tumors. Nat Commun 9:1677 (2018). PubMed: 29700304
  • Lev A  et al. Anti-pancreatic cancer activity of ONC212 involves the unfolded protein response (UPR) and is reduced by IGF1-R and GRP78/BIP. Oncotarget 8:81776-81793 (2017). PubMed: 29137221
  • Pintado C  et al. Neuroinflammation alters cellular proteostasis by producing endoplasmic reticulum stress, autophagy activation and disrupting ERAD activation. Sci Rep 7:8100 (2017). PubMed: 28808322
  • Wang L  et al. Gemcitabine treatment induces endoplasmic reticular (ER) stress and subsequently upregulates urokinase plasminogen activator (uPA) to block mitochondrial-dependent apoptosis in Panc-1 cancer stem-like cells (CSCs). PLoS One 12:e0184110 (2017). PubMed: 28854261
  • Liang P  et al. Fibroblast growth factor 21 protects rat cardiomyocytes from endoplasmic reticulum stress by promoting the fibroblast growth factor receptor 1-extracellular signal-regulated kinase 1/2 signaling pathway. Int J Mol Med 40:1477-1485 (2017). PubMed: 28949374
  • Li Y  et al. Autophagy mediated by endoplasmic reticulum stress enhances the caffeine-induced apoptosis of hepatic stellate cells. Int J Mol Med 40:1405-1414 (2017). PubMed: 28949381
  • Xia D  et al. Knockout of MARCH2 inhibits the growth of HCT116 colon cancer cells by inducing endoplasmic reticulum stress. Cell Death Dis 8:e2957 (2017). PubMed: 28749466
  • Feng S  et al. NS5ABP37 inhibits liver cancer by impeding lipogenesis and cholesterogenesis. Cancer Sci 108:12-22 (2017). WB ; Human . PubMed: 27862769
  • Boß M  et al. AMPK-independent inhibition of human macrophage ER stress response by AICAR. Sci Rep 6:32111 (2016). WB . PubMed: 27562249
  • Qi Y  et al. CDP-diacylglycerol synthases regulate the growth of lipid droplets and adipocyte development. J Lipid Res 57:767-80 (2016). PubMed: 26946540
  • Qi Y  et al. Sphingosine Kinase 1 Protects Hepatocytes from Lipotoxicity via Down-regulation of IRE1a Protein Expression. J Biol Chem 290:23282-90 (2015). PubMed: 26240153
  • Bright MD  et al. Cleavage of BLOC1S1 mRNA by IRE1 Is Sequence Specific, Temporally Separate from XBP1 Splicing, and Dispensable for Cell Viability under Acute Endoplasmic Reticulum Stress. Mol Cell Biol 35:2186-202 (2015). WB . PubMed: 25870107
  • Ruppert T  et al. Molecular and biochemical alterations in tubular epithelial cells of patients with isolated methylmalonic aciduria. Hum Mol Genet 24:7049-59 (2015). PubMed: 26420839
  • Sharma RB  et al. Insulin demand regulates ß cell number via the unfolded protein response. J Clin Invest 125:3831-46 (2015). WB ; Mouse . PubMed: 26389675
  • Zhao C  et al. Autophagy-dependent EIF2AK3 activation compromises ursolic acid-induced apoptosis through upregulation of MCL1 in MCF-7 human breast cancer cells. Autophagy 9:196-207 (2013). PubMed: 23182854
  • Guo X  et al. Patulin induces pro-survival functions via autophagy inhibition and p62 accumulation. Cell Death Dis 4:e822 (2013). Human . PubMed: 24091665
  • Maddalo D  et al. A peptidic unconjugated GRP78/BiP ligand modulates the unfolded protein response and induces prostate cancer cell death. PLoS One 7:e45690 (2012). PubMed: 23049684


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